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Target Organs and Levels of Evidence for TR-339

Toxicology and Carcinogenesis Studies of 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
2-Amino-4-nitrophenol 99-57-0	07/14/1987	Gavage 0,125,250 MG/KG/50 PER GROUP	Physiological Research Laboratory

Levels of Evidence

Male Rats: Some Evidence

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Kidney Tubular Cell: ADENOMA 0/50 1/48 3/50
Non-Neoplastic Lesions	KIDNEY: HYPERPLASIA, TUBULAR CELL 1/50 4/48 5/50

Target Organs and Levels of Evidence for TR-339

Toxicology and Carcinogenesis Studies of 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Levels of Evidence

Male Rats: Some Evidence

Female Rats: No Evidence

Male Mice: No Evidence

Female Mice: No Evidence