https://ntp.niehs.nih.gov/go/8925

Target Organs and Levels of Evidence for TR-364

Toxicology and Carcinogenesis Studies of Rhodamine 6G (C.I. Basic Red 1) (CASRN 989-38-8) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
Rhodamine 6G
989-38-8		 10/04/1988 Dosed-Feed
R: 0, 120, 250, FM: 0, 500, 1000, MM: 0, 1000, 2000 PPM/50 PER GROUP		 Southern Research Institute

Levels of Evidence

Male Rats: Equivocal Evidence
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Skin: KERATOACANTHOMA 1/50 2/50 8/50
Female Rats: Equivocal Evidence
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Adrenal Gland Medulla: PHEOCHROMOCYTOMA 3/50 3/50 8/50 OR MALIGNANT PHEOCHROMOCYTOMA 0/50 0/50 2/50 COMBINED 3/50 3/50 10/50
Male Mice: No Evidence
Female Mice: No Evidence