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2-Chloroacetophenone (CN): Target Organs and Levels of Evidence for TR-379

Toxicology and Carcinogenesis Studies of 2-Chloroacetophenone (CASRN 532-27-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Chemical (Study Title)
Peer Review DateRoute/Exposure LevelsStudy Laboratory
2-Chloroacetophenone (CN)
R: 0,1,2, M: 0,2,4 MG/M3/50 PER GROUP
Battelle Northwest Laboratory

Levels of Evidence

Male Rats: No Evidence
Female Rats: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: FIBROADENOMA 12/50 19/50 23/50
Male Mice: No Evidence
Female Mice: No Evidence