Skip to Main Navigation
Skip to Page Content

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/9142

Chloraminated water: Target Organs and Levels of Evidence for TR-392

Toxicology and Carcinogenesis Studies of Chlorinated Water (CASRNs 7782-50-5 and 7681-52-9) and Chloraminated Water (CASRN 10599-90-3) (Deionized and Charcoal-Filtered) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)

Chemical (Study Title)
CASRN
Peer Review DateRoute/Exposure LevelsStudy Laboratory
Chloraminated water
CHLORAMINEMX
11/19/1990Dosed-Water
R&M: 0,50,100,200 PPM/ 70 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: No Evidence
Female Rats: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: MONONUCLEAR CELL LEUKEMIA 8/50 11/50 15/50 16/50
Male Mice: No Evidence
Female Mice: No Evidence


Chemical (Study Title)
CASRN
Peer Review DateRoute/Exposure LevelsStudy Laboratory
Chlorinated water
CHLORWATERMX
11/19/1990Dosed-Water
R&M: 0,70,140,275 PPM/70 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: No Evidence
Female Rats: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: MONONUCLEAR CELL LEUKEMIA 8/50 7/50 19/51 16/50
Male Mice: No Evidence
Female Mice: No Evidence