Target Organs and Levels of Evidence for TR-425
Toxicology and Carcinogenesis Studies of Promethazine Hydrochloride (CASRN 58-33-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Promethazine hydrochloride 58-33-3 |
Gavage R: 0,3.7,300, M: 0,5,405 MG/10 PER GROUP |
Litton Bionetics, Inc. |
Levels of Evidence: None
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Promethazine hydrochloride 58-33-3 |
12/01/1992 | Gavage R: 0,8.3,16.6,33.3, FM: 0,3.75,7.5,15.0, MM: 0,11.25,22.5,45.0 MG/KG |
T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: No Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Female Rats: No Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Other Considerations |
|