Target Organs and Levels of Evidence for TR-441
Comparative Initiation/Promotion Skin Paint Studies of B6C3F1 Mice, Swiss (CD-1®) Mice, and Sencar Mice
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| Init/prom comparative mouse study (DMBA/TPA/BPO/MNNG) INIT/PROM |
06/21/1994 | Topical Application DMBA/ACETONE(25,2.5,.25UG),DMBA 2.5,TPA 5 UG,BPO 20MG,DMBA/TPA(.25,2.5,25/5UG),DMBA/BPO(2.5,25UG/20MG) AND MNNG/ACETONE(1000,500,100UG),MNNG 100UG,TPA 5UG,BPO 20MG,MNNG/BPO(100,500,1000UG/20MG),MNNG/TPA(1000,1000UG/5UG) |
Battelle Columbus Laboratory |
Levels of Evidence: Not applied to this study
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| Init/prom comparative mouse study (DMBA/TPA/BPO/MNNG) INIT/PROM |
06/21/1994 | Topical Application DMBA/ACETONE(25,2.5,.25UG):DMBA 2.5:TPA 1UG:BPO 20MG:DMBA/TPA(.25,2.5,25/1UG):DMBA/BPO(2.5,25UG/20MG) AND MNNG/ACETONE(1000,500,100UG):MNNG 100UG:TPA 5UG:BPO 20MG:MNNG/BPO(100,500,1000 UG/20MG) |
Battelle Columbus Laboratory |
Levels of Evidence: Not applied to this study
| Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|
| Init/prom comparative mouse study (DMBA/TPA/BPO/MNNG) INIT/PROM |
06/21/1994 | Topical Application DMBA/ACETONE(50,25,2.5UG),DMBA 2.5,TPA 5UG,BPO 20MG,DMBA/TPA(2.5,25,50UG/5UG),DMBA/BPO(2.5,25UG/20MG) AND MNNG/ACETONE(1000,500,100UG),MNNG 100UG,TPA 5UG,BPO 20MG,MNNG/BPO(100,500,1000UG/20MG),MNNG/TPA(100,1000UG/5UG) |
Battelle Columbus Laboratory |