Salicylazosulfapyridine: Target Organs and Levels of Evidence for TR-457
Toxicology and Carcinogenesis Studies of Salicylazosulfapyridine (CASRN 599-79-1) in F344 Rats and B6C3F1 Mice (Gavage Studies)
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Salicylazosulfapyridine 599-79-1 |
Gavage R: 0, 84, 169, OR 337 M: 0, 675, 1350, OR 2700 MG/KG |
T.S.I. Mason Laboratories, Inc. |
Levels of Evidence: None
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Salicylazosulfapyridine 599-79-1 |
06/20/1995 | Gavage R: 84, 168, OR 337.5 MG/KG; 70/GROUP M: 675, 1350, OR 2700 MG/KG; 60/GROUP |
Southern Research Institute |
Levels of Evidence
Male Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Female Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Male Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Female Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Salicylazosulfapyridine 599-79-1 |
06/20/1995 | Gavage | Southern Research Institute |
Levels of Evidence
Male Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Female Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Male Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|
Female Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Other Considerations |
|