Target Organs and Levels of Evidence for TR-470
Toxicology and Carcinogenesis Studies of Pyridine (CASRN 110-86-1) in F344/N Rats, Wistar Rats, and B6C3F1 Mice (Drinking Water Studies)
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Pyridine 110-86-1 |
12/10/1997 | Dosed-Water R: 0, 100, 200, OR 400 PPM MM: 0, 250, 500, OR 1000 PPM FM: 125, 250, OR 500 PPM MWR: 0, 100, 200, OR 400 PPM (50/SEX/GROUP) |
T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Female Rats: Equivocal Evidence
Type | Organ/Tissue (Lesion) |
---|---|
May Have Been Related |
|
Non-Neoplastic Lesions |
|
Male Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Female Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Pyridine 110-86-1 |
12/10/1997 | Dosed-Water | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Equivocal Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|