Target Organs and Levels of Evidence for TR-481
Toxicology and Carcinogenesis Studies of Oleic Acid Diethanolamine Condensate (CASRN 93-83-4) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
Chemical (Study Title) CASRN |
Peer Review Date |
Route/Exposure Levels |
Study Laboratory |
Oleic acid diethanolamine condensate 93-83-4 |
12/10/1997 |
Topical Application R: 0, 50, OR 100 MG/KG; 50/SEX/GROUP M: 0, 15, OR 30 MG/KG; 55/SEX/GROUP |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: No Evidence
Type |
Organ/Tissue (Lesion) |
Non-Neoplastic Lesions |
- SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Female Rats: No Evidence
Type |
Organ/Tissue (Lesion) |
Non-Neoplastic Lesions |
- SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Male Mice: No Evidence
Type |
Organ/Tissue (Lesion) |
Non-Neoplastic Lesions |
- SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Female Mice: No Evidence
Type |
Organ/Tissue (Lesion) |
Non-Neoplastic Lesions |
- SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|