Oleic acid diethanolamine condensate: Target Organs and Levels of Evidence for TR-481
Toxicology and Carcinogenesis Studies of Oleic Acid Diethanolamine Condensate (CASRN 93-83-4) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
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Oleic acid diethanolamine condensate 93-83-4 | 12/10/1997 | Topical Application R: 0, 50, OR 100 MG/KG; 50/SEX/GROUP M: 0, 15, OR 30 MG/KG; 55/SEX/GROUP | Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: No Evidence
Type | Organ/Tissue (Lesion) |
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Non-Neoplastic Lesions | - SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Female Rats: No Evidence
Type | Organ/Tissue (Lesion) |
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Non-Neoplastic Lesions | - SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Male Mice: No Evidence
Type | Organ/Tissue (Lesion) |
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Non-Neoplastic Lesions | - SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|
Female Mice: No Evidence
Type | Organ/Tissue (Lesion) |
---|
Non-Neoplastic Lesions | - SKIN: EPIDERMAL HYPERPLASIA; SEBACEOUS GLAND HYPERPLASIA; HYPERKERATOSIS; ACTIVE DERMAL INFLAMMATION
|