Target Organs and Levels of Evidence for TR-524
Photocarcinogenesis Study of Glycolic Acid and Salicylic Acid (CASRNs 79-14-1 and 69-72-7) in SKH-1 Mice (Simulated Solar Light and Topical Application Studies)
Chemical (Study Title)
CASRN |
Peer Review Date |
Route/Exposure Levels |
Study Laboratory |
alpha/beta Hydroxy acids (glycolic acid, salicylic acid)
HYDROXGLYSAL |
09/27/2005 |
Topical Application |
National Center for Toxicological Research |
Levels of Evidence
Male Mice: No Evidence
| Type |
Organ/Tissue (Lesion) |
| Note |
- SKIN: CARCINOMA IN SITU 0.0 MED SSL 0/18 0/18 0/18 0.3 MED SSL 9/18 4/18 1/18 0.6 MED SSL 13/18 15/18 13/18
- SKIN: CARCINOMA IN SITU OR SQUAMOUS CELL CARCINOMA 0.0 MED SSL 0/18 0/18 0/18 0.3 MED SSL 10/18 4/18 2/18 0.6 MED SSL 18/18 17/18 17/18
|
Female Mice: No Evidence
| Type |
Organ/Tissue (Lesion) |
| Note |
- SKIN: CARCINOMA IN SITU 0.0 MED SSL 0/18 0/18 0/18 0.3 MED SSL 8/18 4/18 0/17 0.6 MED SSL 14/18 11/18 11/18
- SKIN: CARCINOMA IN SITU OR SQUAMOUS CELL CARCINOMA 0.0 MED SSL 0/18 0/18 0/18 0.3 MED SSL 8/18 7/18 2/17 0.6 MED SSL 17/18 17/18 14/18
|
