Target Organs and Levels of Evidence for TR-580
Toxicology and Carcinogenesis Studies of beta-Picoline (CASRN 108-99-6) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
Chemical (Study Title) CASRN |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
beta-Picoline 108-99-6 |
02/08/2012 | Dosed-Water R: 0, 156.25, 312.5, or 625 mg/L M: 0, 312.5, 625, or 1250 mg/L; 50/sex/species/dose |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: No Evidence
Female Rats: Some Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Male Mice: Equivocal Evidence
Type | Organ/Tissue (Lesion) |
---|---|
May Have Been Related |
|
Non-Neoplastic Lesions |
|
Female Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|