Target Organs and Levels of Evidence for TR-583
Toxicology Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid in F344/NTac Rats and B6C3F1/N Mice (Drinking Water Studies)
Chemical CASRN (Study Title) |
Peer Review Date | Route/Exposure Levels | Study Laboratory |
---|---|---|---|
Water disinfection byproducts (Bromodichloroacetic acid) 71133-14-7 |
05/22/2014 | Dosed-Water R&M: 0, 250, 500, or 1000 mg/L; 50/sex/species/dose |
Battelle Columbus Laboratory |
Levels of Evidence
Male Rats: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
May Have Been Related |
|
Non-Neoplastic Lesions |
|
Female Rats: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
May Have Been Related |
|
Non-Neoplastic Lesions |
|
Male Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|
Female Mice: Clear Evidence
Type | Organ/Tissue (Lesion) |
---|---|
Neoplastic Lesions |
|
Non-Neoplastic Lesions |
|