January 19, 2011
Videos
- Webcast Recording (NIH Videocast website, 5 hours, 16 minutes)
Introduction and Public Health Impact of Chemically Induced Eye Injuries
RADM William Stokes, DVM, U.S. Public Health Service, NICEATM, NIEHS
Review of Alternative Test Methods and Integrated Strategies for Ocular Safety Assessments
Jill Merrill, PhD, Center for Drug Evaluation and Research, FDA
Study Director and IACUC Responsibilities: Consideration of Available Reduction, Refinement, and Replacement Alternative Test Methods (USDA)
Jodie Kulpa-Eddy, DVM, Animal and Plant Health Inspection Service, Department of Agriculture
Current Guidelines for Ocular Safety Testing
Deborah McCall, Office of Pesticide Programs, EPA
ICCVAM Evaluation and Recommendations on Best Practices for Incorporating Pain Management and Humane Endpoints in Ocular Safety Testing
RADM William Stokes, DVM, U.S. Public Health Service, NICEATM, NIEHS
The Bovine Corneal Opacity and Permeability (BCOP) Test Method: Validation Status
Elizabeth Lipscomb, PhD, ILS, Contractor Supporting NICEATM
Conducting and Interpreting the BCOP Test Method
Hans Raabe, Institute for In Vitro Sciences, Inc.
The Isolated Chicken Eye Test Method: Validation Status/Conducting and Interpreting the Method
David Allen, PhD, ILS, Contractor Supporting NICEATM
View video on application of liquid test substance to accompany slide 13 [AVI]
View video on application of solid test substance to accompany slide 13 [AVI]
Captioned and narrated versions of videos available on archived webcast: begin at 163 minutes
The Cytosensor Microphysiometer (CM) Test Method: Validation Status
Elizabeth Lipscomb, PhD, ILS, Contractor Supporting NICEATM
Conducting and Interpreting the CM Test Method
Rodger Curren, PhD, Institute for In Vitro Sciences, Inc.
Roundtable Discussion: Regulatory Agency Requirements and Acceptable Alternative Test Methods for Ocular Safety Testing
Alternative Test Methods for Ocular Safety Testing: Case Studies in Breakout Groups
View case study presentations and discussion summaries
New Models in the Validation Pipeline for Ocular Safety Testing