Scientific Advisory Committee on Alternative Toxicological Methods Meeting Final Documents
September 21–22, 2023
Federal Register Notices September 21–22, 2023
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Meeting Materials
September 21–22, 2023
Presentation Abstracts and Background Materials
- Session 1: Five Years into ICCVAM Strategic Roadmap
- Session 2: The Role of New Approach Methodologies (NAMs) in Improving Environmental Health Protection
- Session 3: NICEATM Computational Resources
Public Comments
| Agenda Topic | Name, Affiliation, Sponsorship | Technical and Scientific Public Comments |
|---|---|---|
| Session 1: Five Years Into the ICCVAM Strategic Roadmap | Patricia Bishop, Humane Society of the United States/Danielle Palermo, Human Society Legislative Fund | Public comment received September 14, 2023 |
| Session 1: Five Years Into the ICCVAM Strategic Roadmap | Amy Clippinger and Katherine Groff, People for the Ethical Treatment of Animals | Public comment received September 14, 2023 |
| Session 2: The Role of NAMs in Improving Environmental Health Protection | Amy Clippinger and Katherine Groff, People for the Ethical Treatment of Animals | Public comment received September 14, 2023 |
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Presentations
September 21–22, 2023
September 21, 2023
Five Years Into the ICCVAM Strategic Roadmap: Full Replacement of the Acute Tox Six-Pack
- Roadmap Implementation Plans: Update on Each of the Six-Pack Endpoints, How Close Are We to Replacement?
David Allen, PhD, Inotiv (contractor supporting NICEATM) - Modernizing the Acute Toxicity Six-Pack for U.S. EPA's Office of Chemical Safety and Pollution Prevention
Monique Perron, PhD, U.S. Environmental Protection Agency (EPA) - Beyond the Six-Pack: Strategic Roadmap Future Priorities?
Nicole Kleinstreuer, PhD, NIEHS/NICEATM
Five Years Into the ICCVAM Strategic Roadmap: Evolution of Validation
- ICCVAM Validation Work Group Report
John Gordon, PhD, U.S. Consumer Product Safety Commission - International Harmonization and Global Considerations: Organizational and Financial Aspects of Validation Studies
Anne Gourmelon, Organisation for Economic Co-operation and Development - International Harmonization and Global Considerations: Update of Guidance Document 34 and ICATM Position
Valerie Zuang, PhD, European Commission Joint Research Centre
September 22, 2023
The Role of NAMs in Improving Environmental Health Protection: Population Variability and Susceptibility
- Using NAMs to Address Variability and Susceptibility Across Populations: Report from the October 2022 Symposium Workshop
Helena Hogberg-Durdock, PhD, NIEHS/NICEATM - Building Confidence in New Evidence Streams for Human Health Risk Assessment
Weihsueh Chiu, PhD, Texas A&M University - Fruit Flies for Precision Toxicology
Brian Oliver, PhD, National Institute of Diabetes and Digestive and Kidney Diseases
The Role of NAMs in Improving Environmental Health Protection: Coordinated Responses to Contaminants of Emerging Concern
- An Interagency Initiative to Address Contaminants of Emerging Concern
David Balshaw, PhD, NIEHS - ICCVAM PFAS Workgroup
Natalia Vinas, PhD, U.S. Department of Defense
Computational Resources
- The Integrated Chemical Environment (ICE): Open-Access Tools to Support Chemical Evaluations
Victoria Hull, Inotiv (contractor supporting NICEATM) - OPERA: Open-Source QSAR Models for Regulatory Support
Kamel Mansouri, PhD, NIEHS/NICEATM - Web Application to Predict Skin Sensitization Using Defined Approaches
Kim To, PhD, Inotiv (contractor supporting NICEATM) - ChemMaps.com v2.0: Exploring the Environmental Chemical Universe
Alex Borrel, PhD, Inotiv (contractor supporting NICEATM)