https://ntp.niehs.nih.gov/go/717270

RoC Review of Cumene

Woman pumping gasoline into a silver car

Substance Overview

CASRN: 98-82-8
Status: RoC: Reasonably anticipated to be a human carcinogen

Primary Uses or Exposures

  • An alkylated benzene that is a natural component of petroleum and can also be synthesized from propylene and benzene.
  • Used primarily to produce phenol and acetone (accounting for 98% of all use).
  • People are exposed to cumene via inhalation in workplaces that produce or use cumene, and in gasoline-transport-related jobs.
  • People are exposed to cumene in their everyday lives primarily via breathing contaminated air as a result of its presence in petroleum and petroleum emissions cigarette smoke.
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Documents

Documents for Cumene
Date Document
Aug 30, 2012 RoC Concept
Oct 05, 2012 Literature Search Strategy and List of References - Preliminary
Oct 29, 2012 Report on the Cumene (CASRN 98-82-8) Genotoxicity Studies - Final
Sep 25, 2013

RoC Monograph - Final (Abstract)

Preferred Citation: National Toxicology Program (NTP). 2013. Report on Carcinogens monograph on cumene. Research Triangle Park, NC: National Toxicology Program. RoC Monograph 02. https://doi.org/10.22427/ROC-MGRAPH-02
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Meetings & Events

Listing of related events
Date Event Event Type Materials
Mar 21, 2013

Peer Review of Draft RoC Monographs for 1-Bromopropane and Cumene

Expert Panels - RoC
  • Final Documents

    420391 Final Documents
    March 21-22, 2013

  • Actions
  • Agenda
  • Meeting Materials

    Peer Review of Draft RoC Monographs for 1-Bromopropane and Cumene Meeting Materials
    March 21-22, 2013

    Supplemental materials for some events, meetings, and workshops prior to 2021 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.

  • Presentations

    Peer Review of Draft RoC Monographs for 1-Bromopropane and Cumene Presentations
    March 21-22, 2013

    Supplemental materials for some events, meetings, and workshops prior to 2021 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.
Jun 25, 2013

NTP Board of Scientific Counselors Meeting

Board of Scientific Counselors - BSC Meeting
  • Agenda
  • Meeting Materials

    NTP Board of Scientific Counselors Meeting Meeting Materials
    June 25, 2013

    Supplemental materials for some events, meetings, and workshops prior to 2021 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.

  • Presentations

    NTP Board of Scientific Counselors Meeting Presentations
    June 25, 2013

    Supplemental materials for some events, meetings, and workshops prior to 2021 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.

Supplemental materials for some events, meetings, and workshops prior to 2021 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.
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Public Comments

List of Public Comments for the Report on Carcinogens
Date Received Commenter(s) Affiliation In Response To
Mar 07, 2013 James S. Bus, Ph.D. The Dow Chemical Company Jan 22, 2013 Federal Register notice
Mar 07, 2013 Richard A. Becker, Ph.D., and Jonathan T. Busch American Chemistry Council (ACC) Jan 22, 2013 Federal Register notice
May 14, 2013 Dr. Michael Klein-Boymann CEFIC Phenol & Acetone Producers Sector Group Other
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Note on Accessibility: Persons with disabilities or using assistive technology may find some documents are not fully accessible. For assistance, email us or use our contact form and identify the documents/pages for which access is required. We will assist you in accessing the content of these files. NIEHS has helpful information on accessibility.


Note on Accessibility: Persons with disabilities or using assistive technology may find some documents are not fully accessible. For assistance, email us or use our contact form and identify the documents/pages for which access is required. We will assist you in accessing the content of these files. NIEHS has helpful information on accessibility.