National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/14766

Target Organs and Levels of Evidence for TR-057

Bioassay of ß-TGdR for Possible Carcinogenicity (CASRN 789-61-7)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
beta-Thioguanidine deoxyriboside
789-61-7
02/18/1978Anticancer drugIntraperitoneal Injection
R: 0,3.5,7, M: 0,1,4 MG/KG/35 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Zymbal Gland: (CARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Zymbal Gland: (CARCINOMA)
Male Mice: Inadequate Study
Female Mice: Inadequate Study


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