National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8214

Target Organs and Levels of Evidence for TR-066

Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CASRN 75-34-3)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
1,1-Dichloroethane
75-34-3
01/18/1978Solvent. Cleaning agent. Fumigant. Chemical intermediate. Gavage
MR: 0,382,764 (AVG), FR: 0,475,950 (AVG), MM: 0,1442,2885 (AVG), FM: 0,1665,3331 (AVG) MG/KG/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Negative
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (ADENOCARCINOMA)
  • Vascular System (Unspecified): (HEMANGIOSARCOMA)
Male Mice: Negative
Female Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Uterus/Cervix: (POLYP)


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