National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/10945

Target Organs and Levels of Evidence for TR-106

Bioassay of Trichlorofluoromethane for Possible Carcinogenicity (CASRN 75-69-4)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Trichlorofluoromethane
75-69-4
03/06/1978Aerosol propellant; solvent; refrigerant. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Gavage
MR: 0,488,977 (AVG), FR: 0,538,1077 (AVG), M: 0,1962,3925 (AVG) MG/KG/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study
Male Mice: Negative
Female Mice: Negative


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