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https://ntp.niehs.nih.gov/go/13417

Target Organs and Levels of Evidence for TR-120

Bioassay of Piperonyl Butoxide for Possible Carcinogenicity (CASRN 51-03-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Piperonyl butoxide
51-03-6
08/31/1978Synergist in insecticides with pyrethrins. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
R: 0,5000,10000, M: 0,1036,2804 (AVG) PPM/50 PER GROUP
Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative