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https://ntp.niehs.nih.gov/go/8395

Target Organs and Levels of Evidence for TR-174

Bioassay of p-Phenylenediamine Dihydrochloride for Possible Carcinogenicity (CASRN 624-18-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
p-Phenylenediamine dihydrochloride
624-18-0
10/25/1978Hair dyeDosed-Feed
0,625,1250 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative