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2,3,7,8-Tetrachlorodibenzo-p-dioxin: Target Organs and Levels of Evidence for TR-201

Carcinogenesis Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN 1746-01-6) in Swiss-Webster Mice (Dermal Study)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6	06/27/1980	Topical Application FM: 0,.005, MM: 0,.001 UG/60 PER GROUP	IIT Research Institute

Levels of Evidence

Male Mice: Equivocal

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Subcutaneous Tissue: FIBROSARCOMA 3/42 6/28

Female Mice: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Subcutaneous Tissue: FIBROSARCOMA 2/41 8/27