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Target Organs and Levels of Evidence for TR-234

Carcinogenesis Bioassay of Allyl Isothiocyanate (CASRN 57-06-7) in F344/N Rats and B6C3F1 Mice (Gavage Study)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Allyl isothiocyanate
57-06-7
06/23/1981Flavor agent; in black mustard seed; in cabbage family of vegetablesGavage
0, 12, 25 MG/KG/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: TRANSITIONAL CELL PAPILLOMA 0/49 2/49 4/49
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Subcutaneous Tissue: FIBROSARCOMA 0/50 0/50 3/50


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Allyl isothiocyanate
57-06-7
06/23/1981Flavor agent; in black mustard seed; in cabbage family of vegetablesGavage
0,12,25 MG/KG/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Mice: Negative
Female Mice: Negative