https://ntp.niehs.nih.gov/go/9556

Target Organs and Levels of Evidence for TR-303

Toxicology and Carcinogenesis Studies of 4-Vinylcyclohexene (CASRN 100-40-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
4-Vinylcyclohexene
100-40-3
03/29/1985 Gavage
0,200,400 MG/KG/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study
Male Mice: Inadequate Study
Female Mice: Clear Evidence
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Ovary: GRANULOSA CELL TUMOR 1/49 9/48 11/47 OR CARCINOMA 0/49 1/48 2/47 COMBINED 1/49 10/48 13/47
May Have Been Related
  • Adrenal Gland Cortex: ADENOMA 0/50 3/49 4/48