National Toxicology Program

National Toxicology Program

Target Organs and Levels of Evidence for TR-413

Toxicology and Carcinogenesis Studies of Ethylene Glycol (CASRN 107-21-1) in B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Ethylene glycol
07/09/1991Antifreeze in cooling and heating systems. Extraction solvent. Cleaning agent. Chemical intermediate for polyesters, urethanes, and alkyd resins, vehicle for pharmaceutical preparations, food extracts, flavorings, skin lotions (HSDB 1990). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
MM: 0,.625,1.25,2.5%, FM: 0,1.25,2.5,5.0%/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Mice: No Evidence
Female Mice: No Evidence

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.