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National Toxicology Program

National Toxicology Program

UPDATE NewsletterUPDATE Newsletter

January - June 2022

January

Tissue on a Computer ChipNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

NICEATM requests data from ectoparasiticide efficacy tests; NICEATM-organized workgroup supporting research efforts for COVID Omicron variant; Recent publications.


15th Report on CarcinogensEight substances added to 15th Report on Carcinogens

A chronic bacterial infection, a flame retardant, and six water disinfection byproducts are listed in a new HHS cancer report.


Nicole Kleinstreuer, Ph.D.Impact of variability in animal test data discussed by Kleinstreuer

Nicole Kleinstreuer, Ph.D., spoke with Environmental Factor about her work on a National Academies panel, which held a workshop Dec. 9.


Darlene Dixon, D.V.M., Ph.D., and Robin ArnetteEnvironmental justice workshop unites NIEHS researchers, advocates

Working closely with local community partners, the EJ Workshop Planning Committee emphasized a problems-to-solutions approach.


Brian Berridge, D.V.M., Ph.DStrategic changes position DNTP for focused, innovative research

Yearlong planning by the NIEHS Division of the National Toxicology Program promises more predictive, precise, and preventive science.


February

ICCVAM logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

ICCVAM webinar focuses on (developmental) neurotoxicity; Videos available from recent meetings; Recent publications


Trevor K. Archer, Ph.D.Trevor K. Archer — new Deputy Director of NIEHS — shares his goals, research passion

Archer discussed his proudest scientific achievements, his plans to boost diversity at the institute, and the value of mentorship.


Darlene Dixon, D.V.M., Ph.D.Environmental justice, health disparities top of mind at tox meeting

North Carolina Society of Toxicology event included talks on pollution in communities of color, and NIEHS trainees won research awards.


March

SOT 61st Annual Meeting and ToxExpo, San Diego, CA, March 27-31, 2022NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

NICEATM and ICCVAM activities at SOT; Skin sensitization webinar series concludes March 9; and Recent publications.


Man with lightbulb floating over his handScientific innovation front and center during NIEHS council meeting

Artificial intelligence, virtual reality, machine learning, and other tools will spur breakthroughs and aid research translation, experts said.


Helena Hogberg, Ph.D.Hogberg brings developmental neurotoxicity expertise to NICEATM

Helena Hogberg, Ph.D., has an international perspective on advancing alternatives to animal testing.


Suzanne Fenton, Ph.D.More monitoring of breast milk needed, new research suggests

A study by a U.S.-Canada team estimated PFAS levels in breast milk.


April

Integrated Chemical Environment logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

NICEATM releases ICE 3.6; training workshop April 18-19. ICCVAM member honored by SOT specialty section. NICEATM scientists honored at SOT. ICCVAM member honored by SOT specialty section. NICEATM scientists honored at SOT. Slides and video available for ICCVAM webinar. EPA launches new chemicals collaborative research program; workshop April 20-21


wildfire rages behind a houseComputer modeling teases out chemical toxicants in wildfire smoke

Julia Rager aims to expand understanding of complex environmental mixtures by combining emerging technology with traditional models.


Dori Germolec, Ph.D.New toxicological approaches highlighted at SOT conference

At Society of Toxicology meeting, NIEHS scientists explored innovative research involving PFAS, nonanimal methods, heart disease, and more.


May

ICCVAM logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

ICCVAM public forum May 26-27. NICEATM scientist discusses computational pipeline for cardiotoxicity in May 12 webinar. Proceedings available from workshop on NAMs for human health risk assessment; Next workshop May 12. EURL ECVAM issues status report on alternatives. Videos available from ICE training sessions. Recent publications.


Linda Birnbaum, Ph.D.Yale honors Birnbaum with prestigious public health award

Linda Birnbaum, Ph.D., received the Winslow Medal for her scientific contributions to environmental exposures and human health.


Jonathan Hollander, Ph.D.Advances in neurotoxicology highlighted during NIEHS workshop

The two-day event showcased cutting-edge technology that experts say will shed light on how the environment affects brain health, disease.


June

ICCVAM logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

ICCVAM holds public forum. Session proposal deadline for 12th World Congress extended to June 10. ASCCT annual meeting October 19-21; Abstracts due July 15. Recent publications.


roadway with increasing years written on itFuture research priorities: precision health and predictive tox

National Academies, NIEHS gathered experts to forecast next 10 years of environmental health sciences.


July - December 2022

July

PipettesNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

Recent NICEATM and ICCVAM Publications


Suzanne Fenton, Ph.D.PFAS conference supported by NIEHS engages key stakeholders

EPA uses occasion to announce new health advisories for drinking water standards related to per- and polyfluoroalkyl substances.


Nicole Kleinstreuer, Ph.D.Advances in nonanimal methods showcased at public forum

The event stimulated broad interest and helped stakeholders connect.


August

There were no articles for August 2022.

September

Workshop logoOctober 3-4 workshop to focus on clustering and classification

Registration is open and a preliminary agenda is available for the Clustering and Classification Workshop: Applications to Investigate Adverse Effects of Chemicals on Human Health and Environement.


ICE logoNICEATM releases ICE 3.7

NICEATM released version 3.7 of the Integrated Chemical Environment (ICE) making it easier for users to acces ICE data from other applications.


ICCVAM logoSACATM meeting September 21-22

Registration to view the September 21-22 Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) meeting is open, and an agenda is available for viewing. Written comments and registration to present oral comments are due by Tuesday, September 13.


Diverse Population of PeopleNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

Webinars consider population variability and susceptible populations, NIEHS small business funding opportunities for alternative methods development, EPA to hold NAMs conference October 12-13, and recent NICEATM and ICCVAM publications.


Rick Woychik, Ph.D.NIEHS influences national efforts to understand, solve PFAS problems

Institute research helps to identify health effects, innovate cleanup technologies, and impart evidence to inform policy.


Clemens WittwehrMaking connections to reduce animal use in chemical safety testing

Visiting researcher aims to advance relationships with key stakeholders and increase data integration.


October

ICCVAM logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

ICCVAM 2020-2021 Biennial Report now available; Webinars consider population variability and susceptible populations; EPA offers training on CompTox dashboard and new NAMS training website; OECD publishes new case studies for integrated approaches to testing and assessment; Recent NICEATM publication.


Brian Berridge, D.V.M., Ph.D.A new era: introducing the NIEHS Division of Translational Toxicology

Formerly called the Division of the National Toxicology Program, the organization aims to improve the translational relevance of toxicology research.


Warren Casey, Ph.D.Big questions on reducing animal testing tackled by panel

Experts at federal meeting considered approaches to measuring progress and building confidence in new chemical safety testing methods.


November

ICE logoNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

NICEATM releases ICE 3.7.1; Symposium webinar considers population variability and susceptible populations; OPERA now accessible via QSAR Toolbox; NICEATM and ICCVAM activities at ASCCT;Recent NICEATM publication.


From left to right, NIEHS’ Kelly Shipkowski, Ph.D.; Kristen Ryan, Ph.D.; Anna Kreutz, Ph.D., and Anika Dzierlenga, Ph.D.,Climate, chemicals, and Carolina focus of NCSOT annual conference

At North Carolina Society of Toxicology meeting, NIEHS grantees and trainees discussed how climate change affects health outcomes.


December

Shagun KrishnaNTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

NICEATM Scientist Receives Young Researcher Prize; December 7 Webinar to Discuss Scientific Confidence in NAMs; NIEHS Offers Assistance Applying for Small Business Grants. Apply by December 12; FDA Issues Final Guidance on Carcinogenicity Testing; Animal Welfare Information Center Offers Resources, Training in Searching for Alternatives; Recent NICEATM Publications


Kamel Mansouri, Ph.D.Chemical grouping approaches can aid toxicology research, experts say

NIEHS workshop explored chemical clustering and classification methods that can boost knowledge about how toxicants affect health.


Helena Hogberg, Ph.D.Nonanimal testing experts connect with environmental justice community

Discussions highlighted opportunities and challenges in using new testing approaches to protect susceptible populations.


Erik Tokar, Ph.D.New 3D model shows how cadmium exposure may affect heart development

NIEHS researchers develop new tools to demonstrate how environmental agents can lead to diseases.


The Update Newsletter is produced by NTP Office of Policy, Review, and Outreach. The text is not copyrighted and can be reprinted without permission. If you use parts of the Update Newsletter in your publication, we ask that you provide us with a copy for our records. We welcome your comments and suggestions.

Director of Office of Policy, Review, and Outreach and Editor-in-Chief: Mary Wolfe | Managing Editor: Anna Lee Mosley