Handbook for Preparing Report on Carcinogens Monographs

The handbook gives instructions for conducting the cancer hazard evaluation and preparing the monographs on substances under evaluation. The handbook includes methods for:

• Planning for the evaluation
• Conducting literature searches
• Assessing study quality and sensitivity of individual studies
• Synthesizing evidence across cancer studies to reach preliminary level of evidence conclusions
• Evaluating mechanistic and other relevant data
• Integrating evidence to reach a preliminary listing recommendation

The handbook is a living document and may be updated on a periodic basis.

Downloads

• Handbook for Preparing Report on Carcinogens Monographs (July 20, 2015)
• Standard Search Strings for Literature Database Searches: Appendix to the Draft Handbook for Preparing Report on Carcinogens Monographs (April 1, 2016)