Alternative Testing Models
Study Overview
Description
NTP implements a variety of testing strategies to acquire data about potentially hazardous environmental and occupational substances. These strategies provide additional or more accurate information, strengthen the science base, and inform regulatory decisions.
![Tissue on a chip](/images/tissue-chip-nih-image-archive.jpg)
The purpose of alternative test systems for toxicological research is to replace, reduce, or refine animal use. Systems under development include:
- Computer-based predictive toxicology models
- In vitro cell- and tissue-based systems
- Transcriptomic profiling
- Microphysiological systems ("organs-on-a-chip")
- Fish embryo models
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