Skip to Main Navigation

Skip to Page Content

September 28–29, 2021
Scientific Advisory Committee on Alternative Toxicological Methods Meeting

Videos

Videos and Closed Captioning

September 28, 2021: Morning Session

September 28, 2021: Afternoon Session

September 29, 2021: Morning Session

September 29, 2021: Afternoon Session

Federal Register Notices
September 28–29, 2021

Federal Register notice: PDF HTML

Scientific Advisory Committee on Alternative Toxicological Methods Meeting Meeting Materials
September 28–29, 2021

Presentation Abstracts and Background Materials

Session 1: 2021 Major ICCVAM Accomplishments (Tuesday, September 28)
Session 2a: Ecotoxicology Testing: Regulatory Needs (Tuesday, September 28)
Session 2b: Ecotoxicology Testing: Research Applications (Tuesday, September 28)
Session 3: Evolving Approaches to Validation (Wednesday, September 29)
Session 4: Update on NICEATM Computational Resources (Wednesday, September 29)

Public Comments

Agenda Topic	Name, Affiliation, Sponsorship	Technical and Scientific Public Comments
Evolving Approaches to Validation	Laura Alvarez, Cruelty Free International	Presentation given September 29, 2021
Ecotoxicology Testing Evolving Approaches to Validation	Vicki Katrinak, Humane Society of the United States and Gillian Lyons, Humane Society Legislative Fund	Public comment received September 21, 2021
Evolving Approaches to Validation	Joseph Manuppello, Physicians Committee for Responsible Medicine	Public comment received September 17, 2021
Evolving Approaches to Validation	Erin Hill, Institute for In Vitro Sciences	Public comment received September 16, 2021

Scientific Advisory Committee on Alternative Toxicological Methods Meeting Presentations
September 28–29, 2021

Presentations

September 28, 2021

A Year in Review: ICCVAM Accomplishments in Advancing the 3Rs
Anna Lowit, PhD, U.S. Environmental Protection Agency

Ecotoxicology Testing: Regulatory Needs

Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies
Jessica Leet, PhD, U.S. Department of the Interior
Alternate Models for Acute Fish Toxicity Testing: A Survey
Natalia Garcia-Reyero Vinas, PhD, U.S. Department of Defense
Reduction of Animal Use through Using Fewer Species
William Eckel, PhD, U.S. Environmental Protection Agency

Ecotoxicology Testing: Research Applications

CATMoS: Acute Oral Toxicity Predictions for Environmental Safety Assessment
Kamel Mansouri, PhD, NIEHS/DNTP
The Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) Tool: Catalyzing a Change in Species Extrapolation
Carlie LaLone, PhD, U.S. Environmental Protection Agency

September 29, 2021

Evolving Approaches to Validation

ICCVAM Validation Work Group Update
John Gordon, PhD, U.S. Consumer Product Safety Commission
An OECD Perspective on Building Confidence for New Approach Methodologies
Patience Browne, PhD, Organisation for Economic Co-operation and Development
Implementing the Metrics Workgroup Recommendations: Use of Validated Alternatives
Paul Brown, PhD, U.S. Food and Drug Administration
New ICCVAM Activities for 2021-2022
Warren Casey, PhD, NIEHS/DNTP

Update on NICEATM Computational Resources
Nicole Kleinstreuer, PhD, NIEHS/NTP