June 26-27, 2017
Fishers Lane Conference Center, National Institutes of Health, Bethesda, Maryland
Agenda (updated June 23)
Workshop presentations (Human Toxicology Project Consortium website)
Despite investment of billions of dollars over the past few decades, development of new drugs and other potential disease interventions remains elusive and immensely expensive. There is a growing recognition that, to increase the drug development success rate, a stronger focus on human-relevant data is needed. This data will support implementation of more relevant, efficient methods to understand chemical toxicity based on understanding and functionalizing human biological pathways. A number of projects are underway internationally to mine literature, collect data, and develop these adverse outcome pathways. This workshop brought representatives from several of these projects to a single venue to identify barriers and opportunities and make recommendations regarding what is needed to achieve the goal of fully implementing a human systems-biology platform for understanding disease and improving interventions.
This workshop was co-organized by NICEATM and the Human Toxicology Project Consortium.