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Health Assessment and Translation

About the Office of Health Assessment and Translation

NIEHS and NTP established the Office of Health Assessment and Translation (OHAT) to serve as an environmental health resource for public and regulatory and health agencies (EHP editorial, May 2011). OHAT conducts literature-based evaluations to assess the evidence that environmental chemicals, physical substances, or mixtures (collectively referred to as "substances") may be associated with adverse health effects. OHAT is also active in promoting methods development and harmonization in the conduct of evidence evaluations and systematic review methodology.

The product of an evidence evaluation may be a systematic review, scoping report, interactive evidence map, or workshop report, which may be published as a NTP monograph, NTP technical report, or peer-reviewed journal publication. OHAT develops and communicates NTP conclusions on whether these substances may be of concern for human health.

OHAT was originally established as the Center for the Evaluation of Risks to Human Reproduction (CERHR), which operated from 1998-2010 and focused on assessments of potential adverse effects of environmental substances on reproduction or development.

Background Information

For more background information: