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https://ntp.niehs.nih.gov/go/alt-funding

Funding Opportunities for Test Method Developers

NICEATM and ICCVAM seek to facilitate development of test methods that replace, reduce, and refine the use of animals in testing. In addition, both organizations are committed to the protection of human health, animal health, and the environment. This page lists announcements of funding opportunities intended to support the development of alternative test methods. If you are aware of a funding opportunity that could be included on this page, please contact NICEATM.

SBIR and STTR Omnibus Grant Solicitations of the National Institutes of Health, Centers for Disease Control and Prevention, and Food and Drug Administration

NIEHS is offering funding for small businesses developing technologies of interest to the Tox21 program. These technologies include:

  • Improved or expanded testing methods for toxicity screening
  • Computational approaches for predictive toxicology
  • Technologies such as alternative or improved methods for fixing and preserving tissues

The funding is being offered as part of the 2019 Omnibus Solicitation of the NIH, CDC, and Food and Drug Administration. This funding is available for small business grant applications to support development and commercialization of innovative technologies. View more information on the NIEHS website.

SBIR/STTR Omnibus Solicitations and Accompanying Resources

Next due date: April 5, 2020

For more information about this opportunity, contact:

NIH Funding Resources

The NIEHS SBIR/STTR Program Staff encourages applicants to submit grants at least one week before the deadline and to take advantage of the following resources:

Preproposals Due April 20 for In Vitro Toxicology Grants

CAAT is accepting preproposals for the Alan and Helene Goldberg In Vitro Toxicology Grants program (formerly CAAT Grants Program). These grants of up to $40,000 each will support projects with the potential to significantly reduce or replace the use of laboratory animals. Examples of acceptable projects include providing mechanistic understanding of in vitro responses to toxicants in human cells, development of adverse outcome pathways, or conducting systematic reviews. Consideration should be given to the translation of new methods to evaluate/predict health outcomes. Preproposals for the grants are due Monday, April 20.

NIEHS to Present Webinar on Grant Opportunities for NAM Development

The NIEHS SBIR/STTR program, in coordination with NICEATM, will host a webinar-based town hall meeting on “Development of New Approach Methodologies to Reduce Animal Use in Toxicity Testing.” The webinar will be held on Friday, April 17 from 1:00-3:00 p.m. EDT. 

A key component of the Strategic Roadmap for Establishing New Approaches to Evaluate the Safety of Chemicals and Medical Products in the United States is early interaction between developers of new approach methodologies (NAMs) and end-users, to ensure that the proposed NAMs will meet testing requirements for agency and industry stakeholders. This webinar will facilitate improved communication between method developers, including small business (SBIR/STTR) applicants, and end-users, providing an opportunity for assay developers to hear from ICCVAM stakeholders on the desired characteristics and requirements for NAMs. The agenda will include short presentations from experts from U.S. federal agencies and industries, including pharmaceutical developers, with time allowed for questions from method developers. Presenters include representatives from NICEATM, the U.S. Environmental Protection Agency, the U.S. Food and Drug Administration, the U.S. Department of Defense, 3M Corporation, and Novartis.

ARDF Grants Available, Apply by May 1

The Alternatives Research and Development Foundation (ARDF) awards grants to support research projects that develop alternative methods to advance science and replace or reduce animal use. ARDF is currently accepting applications for this year’s grants, with proposals due May 1

The maximum grant is $40,000. While preference will be given to U.S. applications, proposals are welcome from any nonprofit educational or research institution worldwide. Expert reviews of each proposal will evaluate scientific merit and feasibility and the potential to reduce or replace the use of animals in the near future. Proposals in the fields of research, testing, or education will be considered. Projects may not use intact non-human vertebrate or invertebrate animals. Preference will be given to projects that use:

  • In silico and in vitro methods with human cells or tissues
  • Pathway-based approaches as exemplified by the 2007 National Academy of Sciences report, Toxicity Testing in the Twenty-first Century: A Vision and A Strategy.
Graduate Fellowships Available from IFER

The International Foundation for Ethical Research (IFER) is accepting applications for graduate fellowships. These one-year grants of approximately $12,500 support projects by master’s and Ph.D. students in the sciences. Relevant projects address development, acceptance, and implementation of innovative methods that advance science and refine, reduce, or replace the use of animals in research, testing, or education. Grants are renewable for up to three years, depending on student progress and availability of funds. Special consideration may be given to proposals that are likely to replace the use of animals in research, and for projects that are likely to refine, reduce, or replace the use of nonhuman primates in research. Applications are due Thursday, April 30.