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https://ntp.niehs.nih.gov/go/alt-funding

Funding Opportunities for Test Method Developers

NICEATM and ICCVAM seek to facilitate development of test methods that replace, reduce, and refine the use of animals in testing. In addition, both organizations are committed to the protection of human health, animal health, and the environment. This page lists announcements of funding opportunities intended to support the development of alternative test methods. If you are aware of a funding opportunity that could be included on this page, please contact NICEATM.

On April 17, 2020, the NIEHS SBIR/STTR program in coordination with NICEATM presented a webinar-based town hall meeting, "Development of New Approach Methodologies to Reduce Animal Use in Toxicity Testing." View presentations >>
SBIR and STTR Omnibus Grant Solicitations of the National Institutes of Health, Centers for Disease Control and Prevention, and Food and Drug Administration

NIEHS is offering funding for small businesses developing technologies of interest to the Tox21 program. These technologies include:

  • Tools for exposure assessment, including assessment of exposure to nanomaterials.
  • Improved or expanded testing methods for toxicity screening.
  • Computational approaches for predictive toxicology.
  • Technologies such as alternative or improved methods for fixing and preserving tissues.

The funding is being offered as part of the 2022 Omnibus Solicitation of the NIH, CDC, and Food and Drug Administration. This funding is available for small business grant applications to support development and commercialization of innovative technologies. View more information on the NIEHS website.

SBIR/STTR Omnibus Solicitations and Accompanying Resources

Next due date: April 5, 2023

For more information about this opportunity, contact:

NIH Funding Resources

The NIEHS SBIR/STTR Program Staff encourages applicants to submit grants at least one week before the deadline and to take advantage of the following resources:

Funding Available to Support Translational Use of MPS: Apply by March 28

Three NIH institutes and the U.S. Food and Drug Administration are offering funding to establish research centers that will accelerate the translational use of microphysiological systems (MPS) in drug development through regulatory acceptance and adoption for industrial use. The envisioned centers will support development of MPS that are fit-for-purpose for industry needs, have defined contexts-of-use, and will be developed with consideration of applicable expectations to achieve regulatory approval. These centers will further the development of MPS as drug development tools that, once qualified, will be made publicly and commercially available to fill unmet needs in drug development. U.S.-based nonprofit and for-profit institutions are encouraged to apply for funding; foreign institutions are not eligible. Applications will be accepted beginning February 27 and are due by March 28.

Apply by January 31 for Next Generation Humane Science Award

The Center for Alternatives in Animal Testing (CAAT) at Johns Hopkins University is accepting applications for the Next Generation Humane Science Award, which acknowledges and encourages early-career researchers who focus on replacing the use of animals in research. A first-place award of $5,000 will recognize the work of one scientist; a second-place award of $4,000 may be issued depending on the amount and quality of the applications. Email completed applications to caat@jhu.edu. Application deadline is Sunday, January 31, 2023.

Travel Awards Available for 2023 MPS World Summit

Students and postdoctoral researchers are eligible for 20 travel awards to attend the 2023 MPS World Summit. The meeting will focus on new developments in microphysiological systems (MPS) and application of MPS. European awardees will be reimbursed for $500 in travel costs and $300 in registration fee costs. International awardees will be reimbursed for $1,200 in travel costs and $300 in registration fee costs. Grants are being funded by the National Center for Advancing Translational Sciences of the National Institutes of Health. Apply by January 31, 2023.

Grants Offered to Support Development of Animal-free Antibody Applications

PETA Science Consortium International e.V., the Physicians Committee for Responsible Medicine, and the Alternatives Research and Development Foundation are offering grants for free recombinant antibodies for use in research and testing. Awardees will receive commercially available recombinant antibodies to test in applications that currently use animal-derived antibodies. Applicants should submit a curriculum vitae and a proposal describing in detail the how the antibody will be used. Awardees will be expected to provide updates to grant sponsors on the progress of their work and publish their results. The offering has a rolling deadline, and grant amounts will vary based on details of the projects.

Grants Will Support Development of Tissue Models for Cancer Research

The National Cancer Institute is offering grants to support the development and characterization of state-of-the-art biomimetic tissue-engineered technologies for cancer research. Projects supported by this funding will become part of the Cancer Tissue Engineering Collaborative (TEC) Research Program. The goals of the Cancer TEC Program are to (1) catalyze the advancement of innovative, well-characterized in vitro and ex vivo systems available for cancer research, (2) expand the breadth of these systems to several cancer types, and (3) promote the exploration of cancer phenomena with biomimetic tissue-engineered systems.

Applications for funding were accepted beginning in May 2022, with applications due quarterly through February 2025. Grants of up to $400,000 will be awarded to fund projects that can continue up to five years. Eligibility for these grants is open to for-profit and nonprofit institutions within and outside the United States.