Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/5882

TDMS Study 55312-03 Pathology Tables

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 1
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                                                                           TIME: 14:53:21

                                                         EIS REPORT 37


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  55312B

       CONTRACT NUMBER:  N01-ES-15314

       CAS NUMBER:  68603-42-9

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 2
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 2                      ROOM/AREA:    201         FIRST DOSE: 02/02/93
            SEX: FEMALE                               TRT: 0 MG/KG            PROCEDURE SET:      2
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

153         153  365 02/01/94   449 04/26/94   4/26  Irritation Site of Applic

183         183  505 06/21/94   701 01/03/95   8/26  Irritation Site of Applic

195         195  365 02/01/94   533 07/19/94   7/21  Irritation Site of Applic

200         200  477 05/24/94   533 07/19/94   3/26  Irritation Site of Applic

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 3
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 4                      ROOM/AREA:    201         FIRST DOSE: 02/02/93
            SEX: FEMALE                               TRT: 50 MG/KG           PROCEDURE SET:      2
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

213         213  533 07/19/94   533 07/19/94   1/20  Irritation Site of Applic

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 4
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 6                      ROOM/AREA:    201         FIRST DOSE: 02/02/93
            SEX: FEMALE                               TRT: 100     MG/KG      PROCEDURE SET:      2
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

252         252  365 02/01/94   449 04/26/94   2/26  Irritation Site of Applic

254         254  169 07/20/93   169 07/20/93   1/26  Irritation Site of Applic

257         257  113 05/25/93   113 05/25/93   1/23  Irritation Site of Applic

259         259  113 05/25/93   113 05/25/93   1/26  Irritation Site of Applic

261         261  449 04/26/94   505 06/21/94   2/26  Irritation Site of Applic

264         264  393 03/01/94   421 03/29/94   2/17  Irritation Site of Applic

265         265  421 03/29/94   421 03/29/94   1/24  Irritation Site of Applic

267         267  113 05/25/93   113 05/25/93   1/14  Irritation Site of Applic

269         269  141 06/22/93   141 06/22/93   1/26  Irritation Site of Applic

271         271  365 02/01/94   701 01/03/95   9/26  Irritation Site of Applic

273         273   57 03/30/93    57 03/30/93   1/26  Irritation Site of Applic

276         276  365 02/01/94   533 07/19/94   3/20  Irritation Site of Applic

278         278  113 05/25/93   113 05/25/93   1/26  Irritation Site of Applic

281         281   29 03/02/93   701 01/03/95  14/26  Irritation Site of Applic

284         284  141 06/22/93   141 06/22/93   1/24  Irritation Site of Applic

285         285  617 10/11/94   645 11/08/94   2/26  Papilloma Site of Applic 1
                 673 12/06/94   701 01/03/95   2/26  Irritation Site of Applic

286         286  365 02/01/94   449 04/26/94   4/23  Irritation Site of Applic

289         289  169 07/20/93   365 02/01/94   2/26  Irritation Site of Applic

293         293  113 05/25/93   197 08/17/93   3/10  Irritation Site of Applic

294         294  365 02/01/94   449 04/26/94   2/20  Irritation Site of Applic

295         295   57 03/30/93   449 04/26/94   3/26  Irritation Site of Applic

297         297  505 06/21/94   505 06/21/94   1/26  Irritation Site of Applic

299         299  113 05/25/93   113 05/25/93   1/26  Irritation Site of Applic

300         300  365 02/01/94   365 02/01/94   1/26  Irritation Site of Applic

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 5
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 1                      ROOM/AREA:    201         FIRST DOSE: 02/01/93
            SEX: MALE                                 TRT: 0 MG/KG            PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 6
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 3                      ROOM/AREA:    201         FIRST DOSE: 02/01/93
            SEX: MALE                                 TRT: 50 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

77           77  393 02/28/94   505 06/20/94   5/19  Papilloma Site of Applic 1

90           90  645 11/07/94   673 12/05/94   2/25  Papilloma Site of Applic 1

NTP  EXP/TEST: 55312-03                    COCONUT OIL ACID DIETHANOLAMINE CONDENSATE                             PAGE: 7
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 08/21/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 14:53:21
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: RATS-F 344                          TRT#: 5                      ROOM/AREA:    201         FIRST DOSE: 02/01/93
            SEX: MALE                                 TRT: 100     MG/KG      PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

120         120   57 03/29/93    57 03/29/93   1/26  Irritation Site of Applic

138         138  393 02/28/94   645 11/07/94  10/24  Papilloma Site of Applic 1



                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------