TDMS Study 88036-03 Pathology Tables
NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39
LAB: Battelle Columbus ANTHRAQUINONE DATE: 02/26/99
EXPERIMENT: 88036 TEST: 03 TIME: 08:02:42
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C88036
CONT: N01-ES-25337 CAS: 84-65-1
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39
LAB: BATTELLE COLUMBUS LABORATORY ANTHRAQUINONE DATE: 02/26/99
EXPERIMENT: 88036 TEST: 03 TIME: 8:11:33
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C88036
CONT: N01-ES-25337 CAS: 84-65-1
FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM
---------------- --------------------------------- --------------------------------- ---------------------------------
DOSE/ DOSE/ DOSE/
GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL
FEED/ WEIGHT FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C)
==================================================================================================================================
1 14.6 112.8 14.4 112.2 0.99 60 14.5 114.2 0.99 124 14.3 112.6 0.98 238
2 15.5 149.0 15.3 148.0 0.99 48 14.7 148.6 0.95 97 14.8 148.1 0.95 188
6 17.4 252.2 16.8 246.0 0.97 32 16.5 241.2 0.95 67 16.5 242.0 0.95 128
10 16.9 300.8 16.5 294.4 0.98 26 16.9 293.1 1.00 57 17.0 286.4 1.01 111
14 18.6 335.9 18.1 328.5 0.97 26 17.6 323.3 0.95 53 17.6 316.9 0.95 104
18 17.5 360.9 17.2 354.3 0.98 23 16.6 346.1 0.95 47 16.9 348.6 0.97 91
22 18.3 378.6 17.5 372.8 0.96 22 17.3 366.6 0.95 46 17.3 370.4 0.95 88
26 16.1 395.1 16.5 392.9 1.02 20 16.2 389.2 1.01 41 17.2 389.9 1.07 83
30 17.9 408.5 17.7 407.4 0.99 20 17.6 404.1 0.98 43 17.7 405.3 0.99 82
34 18.2 416.2 17.5 419.1 0.96 20 16.8 413.8 0.92 40 17.4 414.3 0.96 79
38 17.1 423.0 16.9 425.4 0.99 19 16.7 418.3 0.98 39 17.2 419.7 1.01 77
42 17.9 429.8 17.4 432.4 0.97 19 18.3 422.5 1.02 42 17.7 428.9 0.99 77
46 18.2 436.3 17.9 440.0 0.98 19 18.3 433.1 1.01 42 18.5 439.6 1.02 79
50 17.5 440.9 17.2 438.6 0.98 18 17.8 433.8 1.02 40 18.2 437.3 1.04 78
54 18.2 446.6 17.4 443.2 0.96 18 17.6 437.6 0.97 40 17.7 440.4 0.97 76
58 16.9 457.5 16.6 450.3 0.98 17 16.5 443.9 0.98 37 18.0 446.1 1.07 76
62 18.0 466.1 17.8 460.7 0.99 18 17.9 453.2 0.99 39 18.9 456.9 1.05 77
66 17.0 468.3 17.3 461.1 1.02 18 17.5 456.8 1.03 38 18.1 464.2 1.06 73
70 16.6 467.7 16.6 460.8 1.00 17 15.9 452.5 0.96 35 16.5 459.2 0.99 67
74 15.6 470.7 17.1 456.2 1.10 18 16.5 454.7 1.06 36 17.0 458.8 1.09 69
78 15.8 474.9 16.9 457.6 1.07 17 16.4 449.4 1.04 36 16.9 455.8 1.07 69
82 15.8 475.7 16.3 456.4 1.03 17 16.5 446.8 1.04 36 16.1 451.6 1.02 67
86 14.9 471.0 14.7 444.2 0.99 16 15.7 438.5 1.05 35 14.8 441.1 0.99 63
90 16.8 462.4 16.8 442.3 1.00 18 17.5 431.5 1.04 40 17.6 439.8 1.05 75
94 14.0 448.1 15.7 425.3 1.12 17 16.7 426.8 1.19 38 16.3 422.6 1.16 72
98 16.1 449.8 17.0 429.0 1.06 19 16.1 424.8 1.00 37 17.0 418.2 1.06 76
102 14.8 430.3 15.2 405.3 1.03 18 15.4 399.6 1.04 38 17.7 414.2 1.20 80
1 TO 13 WEEKS
----------------
MEAN 16.1 203.7 15.8 200.2 0.98 42 15.6 199.3 0.97 86 15.6 197.3 0.97 166
SD(D) 1.3 1.1 0.01 15 1.2 0.03 31 1.3 0.03 58
CV(E) 8.1 7.3 1.0 36.9 8.0 2.9 35.4 8.3 2.7 34.9
14 TO 52 WEEKS
----------------
MEAN 17.7 402.5 17.4 401.1 0.98 21 17.3 395.1 0.98 43 17.6 397.1 0.99 84
SD(D) 0.7 0.5 0.02 2 0.7 0.04 4 0.5 0.04 8
CV(E) 4.0 2.7 1.9 11.5 4.1 3.6 10.1 2.8 4.1 10.1
> 52 WEEKS
----------------
MEAN 16.2 460.7 16.6 445.6 1.03 17 16.6 439.7 1.03 37 17.1 443.8 1.06 72
SD(D) 1.2 0.9 0.05 1 0.8 0.06 2 1.1 0.06 5
CV(E) 7.6 5.4 4.7 4.5 4.7 5.8 4.5 6.2 6.0 6.8
==================================================================================================================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==========================================
3750 PPM
---------------------------------
DOSE/
GRAMS BODY CONTROL
FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) (GRAMS) DAY(C)
==========================================
1 13.3 112.5 0.91 442
2 14.3 144.9 0.92 370
6 16.0 236.6 0.92 254
10 16.7 284.7 0.99 220
14 17.7 321.6 0.95 206
18 17.0 348.0 0.97 183
22 17.6 365.9 0.96 180
26 16.9 383.2 1.05 166
30 18.4 399.6 1.03 173
34 17.5 408.6 0.96 161
38 17.6 416.6 1.03 159
42 18.1 426.2 1.01 159
46 18.7 430.7 1.03 163
50 17.1 428.7 0.98 149
54 18.4 424.6 1.01 162
58 16.2 430.4 0.96 141
62 17.7 443.6 0.98 149
66 18.0 446.9 1.06 151
70 16.4 443.0 0.99 139
74 17.0 448.5 1.09 142
78 16.3 441.7 1.03 139
82 15.9 437.8 1.01 136
86 16.1 433.6 1.08 139
90 16.6 429.8 0.99 145
94 16.8 419.9 1.20 150
98 16.9 413.8 1.05 153
102 16.4 401.9 1.11 153
1 TO 13 WEEKS
----------------
MEAN 15.1 194.7 0.94 322
SD(D) 1.6 0.04 103
CV(E) 10.4 3.8 32.0
14 TO 52 WEEKS
----------------
MEAN 17.7 392.9 1.00 170
SD(D) 0.6 0.04 16
CV(E) 3.4 3.6 9.7
> 52 WEEKS
----------------
MEAN 16.8 432.0 1.04 146
SD(D) 0.8 0.07 8
CV(E) 4.5 6.3 5.2
==========================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM
---------------- --------------------------------- --------------------------------- ---------------------------------
DOSE/ DOSE/ DOSE/
GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL
FEED/ WEIGHT FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C)
==================================================================================================================================
1 11.3 100.7 11.7 101.3 1.04 54 10.9 102.0 0.96 105 10.4 100.3 0.92 194
2 11.3 118.3 11.5 118.7 1.02 45 10.7 117.4 0.95 90 10.5 116.0 0.93 169
6 10.8 164.6 10.9 160.6 1.01 32 11.1 156.0 1.03 70 10.9 156.1 1.01 132
10 8.9 181.8 9.4 176.3 1.06 25 9.9 171.3 1.11 57 10.3 168.7 1.16 114
14 11.1 195.4 11.0 186.8 0.99 28 10.2 182.3 0.92 55 10.6 184.7 0.95 107
18 10.3 207.6 10.7 198.7 1.04 25 9.1 187.3 0.88 48 9.2 190.5 0.89 90
22 9.8 215.1 9.1 201.8 0.93 21 9.8 195.2 1.00 49 8.8 191.8 0.90 86
26 9.7 226.4 9.5 209.7 0.98 21 9.6 202.6 0.99 46 9.2 198.9 0.95 87
30 10.6 231.2 9.4 213.2 0.89 21 9.8 206.4 0.92 47 9.7 203.2 0.92 90
34 9.9 238.0 10.1 218.2 1.02 22 9.4 209.1 0.95 44 9.4 204.8 0.95 86
38 10.5 241.6 8.9 213.0 0.85 19 10.2 208.8 0.97 48 9.7 205.4 0.92 88
42 10.3 249.7 10.3 225.8 1.00 21 9.7 213.5 0.94 45 10.0 209.6 0.97 90
46 10.3 260.7 10.7 232.0 1.04 22 9.9 219.0 0.96 44 10.2 213.0 0.99 89
50 9.8 261.1 10.3 233.1 1.05 21 10.0 219.4 1.02 45 10.1 214.0 1.03 89
54 11.9 268.5 10.7 238.9 0.90 21 11.2 221.7 0.94 50 10.7 218.8 0.90 91
58 11.3 270.7 10.5 246.8 0.93 20 10.7 230.2 0.95 46 10.7 225.0 0.95 89
62 12.2 293.1 12.1 261.4 0.99 22 11.4 242.9 0.93 46 10.9 234.5 0.89 87
66 11.8 302.4 11.3 267.2 0.96 20 10.9 252.0 0.92 43 11.5 245.4 0.97 88
70 11.2 311.4 11.5 273.2 1.03 20 11.1 257.7 0.99 42 10.6 250.5 0.95 80
74 11.4 318.4 11.3 281.2 0.99 19 12.4 269.6 1.09 45 12.0 261.8 1.05 86
78 10.8 319.7 11.3 284.9 1.05 19 10.8 271.7 1.00 39 11.1 267.2 1.03 78
82 10.9 321.9 11.9 289.6 1.09 19 10.7 275.0 0.98 38 10.5 272.5 0.96 72
86 11.6 330.2 11.2 290.2 0.97 18 11.0 279.5 0.95 39 11.2 276.5 0.97 76
90 11.8 335.4 11.9 298.5 1.01 19 11.4 282.5 0.97 40 11.4 280.8 0.97 76
94 11.7 337.9 12.6 299.0 1.08 20 11.4 280.5 0.97 40 10.1 274.1 0.86 69
98 12.0 345.4 12.0 306.0 1.00 18 12.2 295.5 1.02 41 12.7 287.6 1.06 83
102 12.0 342.5 11.6 305.0 0.97 18 10.9 290.2 0.91 37 11.1 284.4 0.93 73
1 TO 13 WEEKS
----------------
MEAN 10.6 141.3 10.9 139.2 1.03 39 10.7 136.7 1.01 80 10.5 135.3 1.00 152
SD(D) 1.1 1.0 0.02 13 0.5 0.07 21 0.3 0.11 36
CV(E) 10.8 9.3 2.0 33.5 4.9 7.4 26.2 2.9 10.9 23.7
14 TO 52 WEEKS
----------------
MEAN 10.2 232.7 10.0 213.2 0.98 22 9.8 204.4 0.96 47 9.7 201.6 0.95 90
SD(D) 0.4 0.7 0.07 2 0.3 0.04 3 0.5 0.04 6
CV(E) 4.2 7.3 7.1 11.0 3.5 4.3 6.8 5.6 4.5 6.8
> 52 WEEKS
----------------
MEAN 11.6 315.2 11.5 280.1 1.00 19 11.2 265.3 0.97 42 11.1 259.9 0.96 81
SD(D) 0.4 0.6 0.06 1 0.5 0.05 4 0.7 0.06 7
CV(E) 3.9 5.1 5.5 5.7 4.7 4.8 9.0 6.1 6.2 8.9
==================================================================================================================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==========================================
3750 PPM
---------------------------------
DOSE/
GRAMS BODY CONTROL
FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) (GRAMS) DAY(C)
==========================================
1 10.2 101.6 0.90 375
2 11.0 117.3 0.97 352
6 10.9 156.7 1.01 260
10 9.1 165.8 1.02 207
14 10.6 176.7 0.95 226
18 10.2 184.2 0.99 208
22 9.8 191.1 1.00 193
26 9.4 194.6 0.97 181
30 9.9 197.2 0.93 189
34 10.1 201.5 1.02 189
38 9.5 198.7 0.90 179
42 10.0 204.0 0.97 184
46 10.4 208.6 1.01 188
50 10.6 211.0 1.08 188
54 10.6 214.0 0.89 185
58 11.0 221.8 0.97 186
62 11.5 233.5 0.94 185
66 11.0 238.3 0.93 173
70 11.0 248.7 0.98 166
74 11.3 257.9 0.99 164
78 11.6 261.9 1.07 166
82 11.1 264.2 1.02 158
86 11.5 268.1 0.99 161
90 11.6 275.2 0.98 157
94 11.5 271.1 0.98 159
98 12.0 276.8 1.00 163
102 10.9 271.9 0.91 150
1 TO 13 WEEKS
----------------
MEAN 10.3 135.4 0.98 298
SD(D) 0.9 0.05 79
CV(E) 8.4 5.5 26.4
14 TO 52 WEEKS
----------------
MEAN 10.1 196.8 0.98 192
SD(D) 0.4 0.05 14
CV(E) 4.2 5.0 7.4
> 52 WEEKS
----------------
MEAN 11.3 254.1 0.97 167
SD(D) 0.4 0.05 12
CV(E) 3.4 4.9 7.0
==========================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
B 112.8 60 112.2 50 114.2 50 112.6 50 112.5 60
1 14.6 4130 112.8 60 14.4 3425 112.2 50 14.5 3412 114.2 50 14.3 3405 112.6 50 13.3 4120 112.5 60
2 15.5 5760 149.0 60 15.3 4798 148.0 50 14.7 4806 148.6 50 14.8 4496 148.1 50 14.3 5775 144.9 60
5 17.0 4500 16.6 3727 16.2 3712 16.2 3669 16.3 4402
6 17.4 5755 252.2 60 16.8 4834 246.0 50 16.5 4325 241.2 50 16.5 4883 242.0 50 16.0 5876 236.6 60
9 17.6 4245 17.1 3539 17.2 3550 17.5 3557 17.2 4284
10 16.9 5840 300.8 60 16.5 4868 294.4 50 16.9 4897 293.1 50 17.0 4966 286.4 50 16.7 5831 284.7 59
13 17.1 4425 16.9 3711 16.3 3734 17.3 3761 17.0 4410
14 18.6 5651 335.9 60 18.1 4724 328.5 50 17.6 4737 323.3 50 17.6 4754 316.9 50 17.7 5657 321.6 59
17 16.6 4020 15.8 3637 16.7 3612 16.4 3595 16.3 3913
18 17.5 5177 360.9 55 17.2 4721 354.3 50 16.6 4833 346.1 50 16.9 4917 348.6 50 17.0 5138 348.0 54
21 17.1 3974 17.3 3633 17.5 3651 16.8 3662 17.4 3912
22 18.3 5211 378.6 55 17.5 4826 372.8 50 17.3 4943 366.6 50 17.3 4744 370.4 50 17.6 5185 365.9 54
25 16.8 3908 16.5 3566 16.2 3578 16.2 3567 16.6 3859
26 16.1 5316 395.1 55 16.5 4771 392.9 50 16.2 4834 389.2 50 17.2 4885 389.9 50 16.9 5195 383.2 54
29 16.4 4075 16.8 3688 17.4 3711 16.9 3709 17.1 3984
30 17.9 5323 408.5 55 17.7 4811 407.4 50 17.6 4805 404.1 50 17.7 4830 405.3 50 18.4 5158 399.6 54
33 19.5 3753 18.4 3450 18.3 3450 17.9 3450 18.3 3684
34 18.2 5388 416.2 55 17.5 4884 419.1 50 16.8 4864 413.8 50 17.4 4865 414.3 50 17.5 5284 408.6 54
37 16.7 4025 16.3 3718 16.4 3666 16.0 3590 16.8 4016
38 17.1 5376 423.0 55 16.9 4784 425.4 50 16.7 4874 418.3 50 17.2 4489 419.7 49 17.6 5128 416.6 54
41 17.1 4060 16.7 3702 17.0 3729 16.9 3670 16.8 3982
42 17.9 5277 429.8 55 17.4 4816 432.4 50 18.3 4823 422.5 50 17.7 4738 428.9 49 18.1 5170 426.2 54
45 16.5 4170 16.7 3768 17.3 3769 17.0 3707 17.0 4112
46 18.2 5097 436.3 55 17.9 4602 440.0 50 18.3 4445 433.1 49 18.5 4473 439.6 49 18.7 4919 430.7 54
49 17.0 3929 16.7 3585 18.0 3513 17.9 3496 17.6 3862
50 17.5 5325 440.9 55 17.2 4851 438.6 50 17.8 4738 433.8 49 18.2 4723 437.3 49 17.1 5234 428.7 54
53 16.1 3465 17.3 3491 17.5 3459 18.8 3419 17.0 3445
54 18.2 4977 446.6 50 17.4 4932 443.2 50 17.6 4826 437.6 49 17.7 4847 440.4 49 18.4 4794 424.6 49
57 17.3 3535 16.9 3582 17.1 3538 17.9 3532 17.7 3532
58 16.9 4800 457.5 50 16.6 4800 450.3 50 16.5 4742 443.9 49 18.0 4771 446.1 49 16.2 4776 430.4 49
61 17.8 3574 17.6 3574 18.0 3517 19.1 3485 18.2 3427
62 18.0 4686 466.1 50 17.8 4688 460.7 50 17.9 4679 453.2 49 18.9 4621 456.9 49 17.7 4517 443.6 48
65 17.9 3614 17.2 3650 17.6 3519 17.9 3577 17.2 3456
66 17.0 4746 468.3 50 17.3 4659 461.1 50 17.5 4536 456.8 49 18.1 4474 464.2 49 18.0 4515 446.9 48
69 17.2 3482 17.0 3387 15.9 3350 17.2 3434 17.2 3264
70 16.6 4922 467.7 50 16.6 4710 460.8 48 15.9 4694 452.5 48 16.5 4759 459.2 49 16.4 4600 443.0 47
73 17.7 3339 17.4 3423 17.6 3391 17.8 3475 17.7 3266
74 15.6 4625 470.7 48 17.1 4571 456.2 48 16.5 4624 454.7 48 17.0 4705 458.8 49 17.0 4334 448.5 46
77 16.1 3369 16.7 3384 16.7 3393 16.5 3531 16.4 3332
78 15.8 4683 474.9 46 16.9 4745 457.6 48 16.4 4670 449.4 48 16.9 4642 455.8 48 16.3 4398 441.7 45
81 15.3 3249 15.8 3565 16.0 3503 16.2 3572 15.9 3363
82 15.8 4028 475.7 42 16.3 4638 456.4 48 16.5 4499 446.8 46 16.1 4678 451.6 48 15.9 4294 437.8 45
85 15.2 3030 15.1 3474 14.8 3304 14.9 3373 16.4 3236
86 14.9 3881 471.0 41 14.7 4573 444.2 48 15.7 4391 438.5 45 14.8 4445 441.1 46 16.1 4193 433.6 44
89 16.0 2878 16.3 3240 17.8 3123 16.9 3271 17.0 2952
90 16.8 3735 462.4 39 16.8 4256 442.3 45 17.5 4034 431.5 42 17.6 3840 439.8 44 16.6 3888 429.8 40
93 16.4 2507 16.6 2930 16.5 2800 17.3 2874 16.8 2535
94 14.0 3416 448.1 34 15.7 4159 425.3 42 16.7 3697 426.8 38 16.3 4017 422.6 41 16.8 3515 419.9 36
97 17.8 2159 16.9 2580 17.4 2557 18.1 2731 18.8 2423
==================================================================================================================================
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY MALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
98 16.1 2995 449.8 30 17.0 3202 429.0 33 16.1 3503 424.8 35 17.0 3690 418.2 38 16.9 3109 413.8 32
101 14.4 1972 14.8 2422 14.3 2417 15.5 2506 15.8 1821
102 14.8 2383 430.3 25 15.2 2851 405.3 29 15.4 2652 399.6 28 17.7 2890 414.2 31 16.4 2179 401.9 23
MEAN BODY WGT FOR WEEKS
1 TO 13 203.7 200.2 199.3 197.3 194.7
14 TO 52 402.5 401.1 395.1 397.1 392.9
> 52 460.7 445.6 439.7 443.8 432.0
==================================================================================================================================
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
B 100.7 60 101.3 50 102.0 50 100.3 50 101.6 60
1 11.3 4164 100.7 60 11.7 3470 101.3 50 10.9 3472 102.0 50 10.4 3470 100.3 50 10.2 4164 101.6 60
2 11.3 5660 118.3 60 11.5 4730 118.7 50 10.7 4716 117.4 50 10.5 4760 116.0 50 11.0 5671 117.3 60
5 11.3 4302 11.3 3580 11.1 3575 11.1 3570 11.0 4278
6 10.8 5773 164.6 60 10.9 4765 160.6 50 11.1 4820 156.0 50 10.9 4820 156.1 50 10.9 5727 156.7 60
9 11.1 4026 11.1 3360 10.9 3355 9.6 3360 10.9 4038
10 8.9 5845 181.8 60 9.4 4896 176.3 50 9.9 4917 171.3 50 10.3 4929 168.7 50 9.1 6029 165.8 60
13 10.2 4470 10.0 3715 10.2 3649 10.4 3721 9.9 4464
14 11.1 5658 195.4 60 11.0 4755 186.8 50 10.2 4655 182.3 49 10.6 4765 184.7 50 10.6 5768 176.7 60
17 10.4 4046 10.5 3655 9.2 3592 9.5 3668 9.8 4002
18 10.3 5230 207.6 55 10.7 4694 198.7 50 9.1 4663 187.3 49 9.2 4767 190.5 50 10.2 5165 184.2 55
21 9.3 3876 10.0 3553 9.7 3450 9.4 3516 9.9 3905
22 9.8 5314 215.1 55 9.1 4830 201.8 50 9.8 4773 195.2 49 8.8 4923 191.8 50 9.8 5365 191.1 55
25 10.3 3982 9.3 3594 9.2 3550 8.8 3606 9.4 3962
26 9.7 5137 226.4 55 9.5 4853 209.7 50 9.6 4612 202.6 49 9.2 4777 198.9 50 9.4 5339 194.6 55
29 10.3 4119 9.1 3732 9.1 3678 9.3 3746 9.5 4119
30 10.6 5324 231.2 55 9.4 4865 213.2 50 9.8 4741 206.4 49 9.7 4834 203.2 50 9.9 5320 197.2 55
33 9.9 3832 10.0 3573 9.7 3420 9.4 3490 10.1 3951
34 9.9 5351 238.0 55 10.1 4855 218.2 50 9.4 4762 209.1 49 9.4 4860 204.8 50 10.1 5305 201.5 55
37 10.5 4036 9.6 3657 9.8 3605 9.9 3673 9.9 3673
38 10.5 5377 241.6 55 8.9 4974 213.0 50 10.2 4761 208.8 49 9.7 4845 205.4 50 9.5 5494 198.7 55
41 10.9 4001 10.2 3660 9.7 3547 9.3 3620 10.0 3999
42 10.3 4896 249.7 55 10.3 4353 225.8 50 9.7 4239 213.5 49 10.0 4339 209.6 50 10.0 4364 204.0 55
45 11.3 4037 9.4 3670 11.0 3597 10.0 3669 9.9 4042
46 10.3 5216 260.7 55 10.7 4632 232.0 50 9.9 4668 219.0 49 10.2 4782 213.0 50 10.4 5116 208.6 55
49 9.7 3808 10.3 3435 9.9 3388 9.9 3445 11.0 3782
50 9.8 4797 261.1 55 10.3 4305 233.1 50 10.0 4244 219.4 49 10.1 4820 214.0 50 10.6 5274 211.0 55
53 10.4 3534 10.1 3535 10.6 3479 9.5 3591 10.6 3594
54 11.9 4945 268.5 50 10.7 4913 238.9 50 11.2 4799 221.7 49 10.7 4851 218.8 50 10.6 4835 214.0 50
57 11.4 3193 10.7 3555 11.4 3485 10.2 3550 11.3 3569
58 11.3 4348 270.7 50 10.5 4892 246.8 50 10.7 4739 230.2 49 10.7 4794 225.0 50 11.0 4892 221.8 50
61 12.4 3627 11.9 3610 11.8 3489 11.5 3615 12.0 3545
62 12.2 4758 293.1 50 12.1 4711 261.4 50 11.4 4679 242.9 49 10.9 4731 234.5 50 11.5 4880 233.5 50
65 11.9 3600 12.0 3600 11.9 3530 11.5 3581 11.5 3584
66 11.8 4836 302.4 50 11.3 4932 267.2 50 10.9 4704 252.0 49 11.5 4673 245.4 50 11.0 4801 238.3 50
69 11.8 3612 11.7 3610 11.1 3636 11.3 3710 11.5 3714
70 11.2 4765 311.4 50 11.5 4931 273.2 50 11.1 4613 257.7 49 10.6 4649 250.5 50 11.0 4818 248.7 50
73 11.4 3662 12.0 3569 11.1 3444 12.5 3566 11.9 3487
74 11.4 4769 318.4 50 11.3 4809 281.2 50 12.4 4548 269.6 48 12.0 4730 261.8 50 11.3 4692 257.9 49
77 11.1 3643 10.9 3582 11.1 3434 11.1 3587 10.7 3577
78 10.8 4825 319.7 50 11.3 4708 284.9 49 10.8 4628 271.7 48 11.1 4825 267.2 50 11.6 4429 261.9 48
81 11.3 3293 11.9 3292 11.0 3226 11.0 3293 11.4 3228
82 10.9 4925 321.9 49 11.9 4834 289.6 49 10.7 4818 275.0 48 10.5 4935 272.5 49 11.1 4765 264.2 48
85 12.6 3245 10.8 3318 12.2 3178 11.7 3461 12.1 3395
86 11.6 4462 330.2 46 11.2 4503 290.2 46 11.0 4407 279.5 45 11.2 4654 276.5 49 11.5 4710 268.1 48
89 12.1 3102 12.7 3321 11.9 3317 11.8 3553 11.8 3440
90 11.8 4124 335.4 43 11.9 4315 298.5 45 11.4 4031 282.5 45 11.4 4588 280.8 48 11.6 4577 275.2 48
93 12.1 2769 13.0 2974 11.8 2977 12.6 3103 12.1 3342
94 11.7 3749 337.9 39 12.6 4186 299.0 43 11.4 4247 280.5 43 10.1 4400 274.1 44 11.5 4819 271.1 48
97 11.7 2507 12.5 3086 13.1 2657 12.6 3137 12.3 3445
==================================================================================================================================
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY FEMALE RATS IN THE
CHRONIC DOSED FEED STUDY OF ANTHRAQUINONE
==================================================================================================================================
0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
98 12.0 3198 345.4 33 12.0 4138 306.0 42 12.2 3881 295.5 40 12.7 4116 287.6 43 12.0 4646 276.8 48
101 11.3 2114 11.7 2885 11.2 2769 12.0 2888 11.0 3239
102 12.0 2730 342.5 28 11.6 3994 305.0 41 10.9 3698 290.2 38 11.1 3895 284.4 40 10.9 4462 271.9 46
MEAN BODY WGT FOR WEEKS
1 TO 13 141.3 139.2 136.7 135.3 135.4
14 TO 52 232.7 213.2 204.4 201.6 196.8
> 52 315.2 280.1 265.3 259.9 254.1
==================================================================================================================================
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.