Oleic Acid Diethanolamine Condensate
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 1
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION TIME: 13:27:08
EIS REPORT 37
FACILITY: Battelle Columbus Laboratory
NTP C#: C91014
CONTRACT NUMBER: NO1-ES-15314
CAS NUMBER: 93-83-4
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 2
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 2 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
155 155 470 09/01/94 498 09/29/94 2/18 Irritation Site of Applic
168 168 330 04/14/94 722 05/11/95 15/26 Irritation Site of Applic
169 169 666 03/16/95 666 03/16/95 1/24 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 3
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 4 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 50 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
201 201 189 11/24/93 274 02/17/94 4/10 Irritation Site of Applic
202 202 162 10/28/93 386 06/09/94 7/14 Irritation Site of Applic
203 203 189 11/24/93 722 05/11/95 20/26 Irritation Site of Applic
204 204 722 05/11/95 722 05/11/95 1/26 Irritation Site of Applic
206 206 189 11/24/93 722 05/11/95 15/26 Irritation Site of Applic
207 207 162 10/28/93 526 10/27/94 13/19 Irritation Site of Applic
208 208 274 02/17/94 526 10/27/94 9/19 Irritation Site of Applic
209 209 218 12/23/93 526 10/27/94 12/19 Irritation Site of Applic
210 210 246 01/20/94 722 05/11/95 18/26 Irritation Site of Applic
211 211 162 10/28/93 666 03/16/95 19/24 Irritation Site of Applic
212 212 162 10/28/93 610 01/19/95 17/22 Irritation Site of Applic
213 213 189 11/24/93 666 03/16/95 18/24 Irritation Site of Applic
214 214 189 11/24/93 722 05/11/95 16/26 Irritation Site of Applic
215 215 162 10/28/93 666 03/16/95 14/26 Irritation Site of Applic
216 216 134 09/30/93 694 04/13/95 16/26 Irritation Site of Applic
217 217 162 10/28/93 722 05/11/95 12/26 Irritation Site of Applic
218 218 162 10/28/93 638 02/16/95 16/23 Irritation Site of Applic
219 219 162 10/28/93 666 03/16/95 17/24 Irritation Site of Applic
220 220 246 01/20/94 386 06/09/94 5/26 Irritation Site of Applic
221 221 162 10/28/93 722 05/11/95 20/26 Irritation Site of Applic
222 222 246 01/20/94 553 11/23/94 6/20 Irritation Site of Applic
223 223 218 12/23/93 274 02/17/94 2/13 Irritation Site of Applic
225 225 162 10/28/93 330 04/14/94 2/19 Irritation Site of Applic
226 226 162 10/28/93 330 04/14/94 4/20 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 4
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 4 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 50 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
227 227 582 12/22/94 722 05/11/95 5/26 Irritation Site of Applic
228 228 218 12/23/93 638 02/16/95 10/24 Irritation Site of Applic
229 229 274 02/17/94 498 09/29/94 9/18 Irritation Site of Applic
230 230 246 01/20/94 330 04/14/94 4/26 Irritation Site of Applic
231 231 218 12/23/93 218 12/23/93 1/8 Irritation Site of Applic
232 232 218 12/23/93 246 01/20/94 2/9 Irritation Site of Applic
233 233 189 11/24/93 694 04/13/95 19/25 Irritation Site of Applic
234 234 162 10/28/93 722 05/11/95 18/26 Irritation Site of Applic
236 236 162 10/28/93 526 10/27/94 13/19 Irritation Site of Applic
238 238 246 01/20/94 722 05/11/95 4/26 Irritation Site of Applic
239 239 218 12/23/93 358 05/12/94 4/19 Irritation Site of Applic
240 240 189 11/24/93 386 06/09/94 6/19 Irritation Site of Applic
241 241 246 01/20/94 610 01/19/95 5/24 Irritation Site of Applic
242 242 358 05/12/94 722 05/11/95 5/26 Irritation Site of Applic
243 243 246 01/20/94 358 05/12/94 4/26 Irritation Site of Applic
244 244 274 02/17/94 638 02/16/95 11/23 Irritation Site of Applic
245 245 218 12/23/93 722 05/11/95 16/26 Irritation Site of Applic
246 246 189 11/24/93 722 05/11/95 9/26 Irritation Site of Applic
247 247 189 11/24/93 414 07/07/94 9/15 Irritation Site of Applic
248 248 189 11/24/93 274 02/17/94 4/10 Irritation Site of Applic
249 249 246 01/20/94 246 01/20/94 1/18 Irritation Site of Applic
250 250 189 11/24/93 553 11/23/94 3/22 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 5
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 6 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 100MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
251 251 106 09/02/93 722 05/11/95 23/26 Irritation Site of Applic
252 252 106 09/02/93 582 12/22/94 18/21 Irritation Site of Applic
253 253 134 09/30/93 330 04/14/94 7/12 Irritation Site of Applic
254 254 106 09/02/93 442 08/04/94 13/16 Irritation Site of Applic
255 255 106 09/02/93 526 10/27/94 16/19 Irritation Site of Applic
256 256 106 09/02/93 666 03/16/95 19/24 Irritation Site of Applic
257 257 106 09/02/93 553 11/23/94 17/20 Irritation Site of Applic
258 258 134 09/30/93 694 04/13/95 21/25 Irritation Site of Applic
259 259 78 08/05/93 498 09/29/94 16/18 Irritation Site of Applic
260 260 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
261 261 134 09/30/93 274 02/17/94 6/10 Irritation Site of Applic
262 262 106 09/02/93 722 05/11/95 23/26 Irritation Site of Applic
263 263 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
264 264 134 09/30/93 553 11/23/94 16/20 Irritation Site of Applic
265 265 134 09/30/93 526 10/27/94 15/19 Irritation Site of Applic
266 266 134 09/30/93 330 04/14/94 8/12 Irritation Site of Applic
267 267 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
268 268 134 09/30/93 553 11/23/94 16/20 Irritation Site of Applic
269 269 106 09/02/93 722 05/11/95 23/26 Irritation Site of Applic
270 270 134 09/30/93 638 02/16/95 19/23 Irritation Site of Applic
271 271 134 09/30/93 162 10/28/93 2/6 Irritation Site of Applic
272 272 106 09/02/93 526 10/27/94 16/19 Irritation Site of Applic
273 273 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
274 274 106 09/02/93 666 03/16/95 21/24 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 6
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 6 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 100MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
275 275 134 09/30/93 330 04/14/94 8/12 Irritation Site of Applic
276 276 134 09/30/93 442 08/04/94 12/16 Irritation Site of Applic
277 277 106 09/02/93 722 05/11/95 23/26 Irritation Site of Applic
278 278 78 08/05/93 498 09/29/94 15/18 Irritation Site of Applic
279 279 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
280 280 106 09/02/93 722 05/11/95 22/26 Irritation Site of Applic
281 281 106 09/02/93 553 11/23/94 17/20 Irritation Site of Applic
282 282 106 09/02/93 666 03/16/95 21/24 Irritation Site of Applic
283 283 134 09/30/93 498 09/29/94 14/18 Irritation Site of Applic
284 284 134 09/30/93 694 04/13/95 21/25 Irritation Site of Applic
285 285 134 09/30/93 302 03/17/94 7/11 Irritation Site of Applic
286 286 106 09/02/93 610 01/19/95 19/22 Irritation Site of Applic
287 287 134 09/30/93 722 05/11/95 21/26 Irritation Site of Applic
288 288 106 09/02/93 386 06/09/94 11/14 Irritation Site of Applic
289 289 106 09/02/93 162 10/28/93 3/6 Irritation Site of Applic
290 290 106 09/02/93 722 05/11/95 23/26 Irritation Site of Applic
291 291 78 08/05/93 414 07/07/94 13/15 Irritation Site of Applic
292 292 134 09/30/93 722 05/11/95 22/26 Irritation Site of Applic
293 293 134 09/30/93 414 07/07/94 11/15 Irritation Site of Applic
294 294 78 08/05/93 302 03/17/94 8/11 Irritation Site of Applic
295 295 134 09/30/93 722 05/11/95 21/26 Irritation Site of Applic
296 296 134 09/30/93 498 09/29/94 14/18 Irritation Site of Applic
297 297 134 09/30/93 498 09/29/94 14/18 Irritation Site of Applic
298 298 78 08/05/93 722 05/11/95 23/26 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 7
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 6 ROOM/AREA: 203 FIRST DOSE: 05/20/93
SEX: FEMALE TRT: 100MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
299 299 134 09/30/93 610 01/19/95 18/22 Irritation Site of Applic
300 300 106 09/02/93 553 11/23/94 17/20 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 8
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 1 ROOM/AREA: 203 FIRST DOSE: 05/19/93
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 9
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 3 ROOM/AREA: 203 FIRST DOSE: 05/19/93
SEX: MALE TRT: 50 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
54 54 610 01/18/95 610 01/18/95 1/22 Irritation Site of Applic
63 63 582 12/21/94 722 05/10/95 6/26 Irritation Site of Applic
65 65 386 06/08/94 386 06/08/94 1/22 Irritation Site of Applic
66 66 218 12/22/93 218 12/22/93 1/24 Irritation Site of Applic
68 68 554 11/23/94 554 11/23/94 1/20 Irritation Site of Applic
74 74 302 03/16/94 610 01/18/95 2/22 Irritation Site of Applic
75 75 302 03/16/94 302 03/16/94 1/19 Irritation Site of Applic
77 77 358 05/11/94 358 05/11/94 1/22 Irritation Site of Applic
79 79 302 03/16/94 302 03/16/94 1/26 Irritation Site of Applic
80 80 246 01/19/94 610 01/18/95 2/22 Irritation Site of Applic
82 82 274 02/16/94 274 02/16/94 1/24 Irritation Site of Applic
83 83 134 09/29/93 134 09/29/93 1/22 Irritation Site of Applic
85 85 302 03/16/94 302 03/16/94 1/23 Irritation Site of Applic
92 92 722 05/10/95 722 05/10/95 1/26 Irritation Site of Applic
94 94 134 09/29/93 274 02/16/94 4/26 Irritation Site of Applic
96 96 358 05/11/94 358 05/11/94 1/21 Irritation Site of Applic
97 97 190 11/24/93 190 11/24/93 1/25 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 10
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 5 ROOM/AREA: 203 FIRST DOSE: 05/19/93
SEX: MALE TRT: 100MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
101 101 134 09/29/93 134 09/29/93 1/25 Irritation Site of Applic
102 102 134 09/29/93 302 03/16/94 3/23 Irritation Site of Applic
103 103 134 09/29/93 134 09/29/93 1/20 Irritation Site of Applic
106 106 722 05/10/95 722 05/10/95 1/26 Irritation Site of Applic
109 109 134 09/29/93 246 01/19/94 3/17 Irritation Site of Applic
110 110 134 09/29/93 722 05/10/95 12/26 Irritation Site of Applic
111 111 134 09/29/93 162 10/27/93 2/26 Irritation Site of Applic
113 113 274 02/16/94 666 03/15/95 4/26 Irritation Site of Applic
114 114 274 02/16/94 274 02/16/94 1/26 Irritation Site of Applic
115 115 134 09/29/93 134 09/29/93 1/19 Irritation Site of Applic
117 117 610 01/18/95 722 05/10/95 5/26 Irritation Site of Applic
118 118 582 12/21/94 582 12/21/94 1/26 Irritation Site of Applic
119 119 302 03/16/94 302 03/16/94 1/19 Irritation Site of Applic
121 121 134 09/29/93 134 09/29/93 1/25 Irritation Site of Applic
123 123 134 09/29/93 638 02/15/95 2/23 Irritation Site of Applic
124 124 190 11/24/93 610 01/18/95 2/23 Irritation Site of Applic
127 127 582 12/21/94 582 12/21/94 1/23 Irritation Site of Applic
128 128 246 01/19/94 358 05/11/94 3/19 Irritation Site of Applic
131 131 610 01/18/95 610 01/18/95 1/22 Irritation Site of Applic
132 132 302 03/16/94 442 08/03/94 2/22 Irritation Site of Applic
133 133 246 01/19/94 330 04/13/94 2/25 Irritation Site of Applic
134 134 302 03/16/94 694 04/12/95 5/25 Irritation Site of Applic
135 135 162 10/27/93 414 07/06/94 8/24 Irritation Site of Applic
136 136 582 12/21/94 582 12/21/94 1/23 Irritation Site of Applic
NTP EXP/TEST: 91014-03 OLEIC ACID DIETHANOLAMINE CONDENSATE PAGE: 11
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/14/97
ROUTE: SKIN APPLICATION EISRPT37 TIME: 13:27:08
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SPECIES-STRAIN: RATS-F 344 TRT#: 5 ROOM/AREA: 203 FIRST DOSE: 05/19/93
SEX: MALE TRT: 100MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- --------------------
137 137 302 03/16/94 302 03/16/94 1/19 Irritation Site of Applic
139 139 246 01/19/94 302 03/16/94 3/26 Irritation Site of Applic
141 141 470 08/31/94 722 05/10/95 10/26 Irritation Site of Applic
143 143 190 11/24/93 302 03/16/94 5/20 Irritation Site of Applic
144 144 246 01/19/94 246 01/19/94 1/22 Irritation Site of Applic
146 146 610 01/18/95 610 01/18/95 1/23 Irritation Site of Applic
149 149 610 01/18/95 638 02/15/95 2/24 Irritation Site of Applic
150 150 694 04/12/95 694 04/12/95 1/26 Irritation Site of Applic
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