TDMS Study 97013-06 Pathology Tables
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION TIME: 08:51:32
EIS REPORT 37
FACILITY: Battelle Columbus Laboratory
NTP C#: 97013F
CONTRACT NUMBER: NO1-ES-65406
CAS NUMBER: 75-27-4
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 2 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 3
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 4 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 64 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
485 485 106 12/02/99 106 12/02/99 1/26 Irritation Site Of Application
162 01/27/00 176 02/10/00 3/26 Papilloma Site Of Application Small 1
REMOVED ** CID 485 ** REASON - TSAC
184 02/18/00 Papilloma Site Of Application Small 1
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 4
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 6 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 128 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
491 491 155 01/20/00 155 01/20/00 1/26 Irritation Site Of Application
REMOVED ** CID 491 ** REASON - TSAC
184 02/18/00 Mass Torso/Ventral Small 1
495 495 134 12/30/99 134 12/30/99 1/26 Irritation Site Of Application
REMOVED ** CID 495 ** REASON - TSAC
184 02/18/00 Unremarkable
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 5
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 8 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 256 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
510 510 134 12/30/99 134 12/30/99 1/26 Irritation Site Of Application
REMOVED ** CID 510 ** REASON - TSAC
184 02/18/00 Unremarkable
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 6
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
536 536 99 11/25/99 106 12/02/99 2/24 Papilloma Site Of Application Medium 1
113 12/09/99 113 12/09/99 1/24 Papilloma Site Of Application Small 10
106 12/02/99 106 12/02/99 1/24 Papilloma Site Of Application Small 2
120 12/16/99 120 12/16/99 1/24 Papilloma Site Of Application Medium 2
162 01/27/00 162 01/27/00 1/24 Papilloma Site Of Application Small 20
134 12/30/99 155 01/20/00 4/24 Papilloma Site Of Application Small 5
57 10/14/99 127 12/23/99 3/24 Papilloma Site Of Application Small 6
64 10/21/99 64 10/21/99 1/24 Papilloma Site Of Application Small 7
120 12/16/99 120 12/16/99 1/24 Papilloma Site Of Application Small 8
REMOVED ** CID 536 ** REASON - Other
168 02/02/00 Papilloma Site Of Application Small 20
537 537 43 09/30/99 43 09/30/99 1/11 Irritation Site Of Application
64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Small 12
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 537 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
538 538 99 11/25/99 99 11/25/99 1/17 Papilloma Site Of Application Small 10
85 11/11/99 85 11/11/99 1/17 Papilloma Site Of Application Small 2
106 12/02/99 106 12/02/99 1/17 Papilloma Site Of Application Small 20
92 11/18/99 92 11/18/99 1/17 Papilloma Site Of Application Small 7
113 12/09/99 113 12/09/99 1/17 Papilloma Site Of Application Medium 9
113 12/09/99 113 12/09/99 1/17 Papilloma Site Of Application Small 9
REMOVED ** CID 538 ** REASON - Other
114 12/10/99 Mass Torso/Ventral Medium 1
114 12/10/99 Papilloma Site Of Application Small 6
114 12/10/99 Papilloma Site Of Application Medium 9
114 12/10/99 Papilloma Site Of Application Large 5
539 539 50 10/07/99 50 10/07/99 1/24 Irritation Site Of Application
113 12/09/99 155 01/20/00 7/24 Papilloma Site Of Application Small 15
71 10/28/99 71 10/28/99 1/24 Papilloma Site Of Application Small 2
106 12/02/99 162 01/27/00 2/24 Papilloma Site Of Application Small 20
78 11/04/99 78 11/04/99 1/24 Papilloma Site Of Application Small 4
85 11/11/99 99 11/25/99 3/24 Papilloma Site Of Application Small 5
REMOVED ** CID 539 ** REASON - Other
168 02/02/00 Papilloma Site Of Application Small 20
540 540 57 10/14/99 57 10/14/99 1/11 Papilloma Site Of Application Small 12
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 7
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
- CONTINUATION OF PREVIOUS ANIMAL DATA -
540 540 64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Small 16
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 540 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
541 541 78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 10
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 16
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 8
REMOVED ** CID 541 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
542 542 57 10/14/99 57 10/14/99 1/11 Papilloma Site Of Application Small 13
64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Small 17
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 542 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
543 543 64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Small 12
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
57 10/14/99 57 10/14/99 1/11 Papilloma Site Of Application Small 8
REMOVED ** CID 543 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
544 544 85 11/11/99 92 11/18/99 2/14 Papilloma Site Of Application Small 20
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 8
REMOVED ** CID 544 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
545 545 43 09/30/99 50 10/07/99 2/14 Irritation Site Of Application
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Medium 1
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 14
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Medium 2
85 11/11/99 92 11/18/99 2/14 Papilloma Site Of Application Small 20
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 9
REMOVED ** CID 545 ** REASON - Other
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 8
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
- CONTINUATION OF PREVIOUS REMOVAL DATA -
545 545 96 11/22/99 Papilloma Site Of Application Small 20
96 11/22/99 Papilloma Site Of Application Medium 2
546 546 64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Small 16
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 546 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
547 547 43 09/30/99 43 09/30/99 1/14 Irritation Site Of Application
64 10/21/99 64 10/21/99 1/14 Papilloma Site Of Application Small 14
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 16
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 17
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 18
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
REMOVED ** CID 547 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
548 548 57 10/14/99 57 10/14/99 1/11 Papilloma Site Of Application Small 15
64 10/21/99 64 10/21/99 1/11 Papilloma Site Of Application Medium 16
71 10/28/99 71 10/28/99 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 548 ** REASON - Other
76 11/02/99 Papilloma Site Of Application Small 20
549 549 71 10/28/99 78 11/04/99 2/17 Irritation Site Of Application
113 12/09/99 113 12/09/99 1/17 Papilloma Site Of Application Small 15
106 12/02/99 106 12/02/99 1/17 Papilloma Site Of Application Small 20
99 11/25/99 99 11/25/99 1/17 Papilloma Site Of Application Small 8
REMOVED ** CID 549 ** REASON - Other
114 12/10/99 Papilloma Site Of Application Small 20
550 550 71 10/28/99 71 10/28/99 1/14 Irritation Site Of Application
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
REMOVED ** CID 550 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 9
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 1 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 10
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 3 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 64 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 11
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 5 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 128 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
431 431 148 01/13/00 148 01/13/00 1/26 Irritation Site Of Application
REMOVED ** CID 431 ** REASON - TSAC
183 02/17/00 Unremarkable
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 12
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 7 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 256 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
453 453 71 10/28/99 78 11/04/99 2/26 Irritation Site Of Application
REMOVED ** CID 453 ** REASON - TSAC
183 02/17/00 Mass Torso/Ventral Small 1
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 13
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: TPA PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
521 521 50 10/07/99 50 10/07/99 1/14 Irritation Site Of Application
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 16
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 8
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 9
REMOVED ** CID 521 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
522 522 64 10/21/99 78 11/04/99 3/14 Papilloma Site Of Application Small 12
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 15
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
57 10/14/99 57 10/14/99 1/14 Papilloma Site Of Application Small 4
REMOVED ** CID 522 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
523 523 78 11/04/99 78 11/04/99 1/12 Papilloma Site Of Application Medium 1
71 10/28/99 71 10/28/99 1/12 Papilloma Site Of Application Small 17
78 11/04/99 78 11/04/99 1/12 Papilloma Site Of Application Small 20
64 10/21/99 64 10/21/99 1/12 Papilloma Site Of Application Medium 8
57 10/14/99 57 10/14/99 1/12 Papilloma Site Of Application Small 8
REMOVED ** CID 523 ** REASON - Other
79 11/05/99 Papilloma Site Of Application Small 20
524 524 71 10/28/99 78 11/04/99 2/14 Papilloma Site Of Application Medium 1
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 11
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 13
85 11/11/99 92 11/18/99 2/14 Papilloma Site Of Application Medium 2
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
57 10/14/99 64 10/21/99 2/14 Papilloma Site Of Application Small 3
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 4
REMOVED ** CID 524 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
96 11/22/99 Papilloma Site Of Application Medium 2
525 525 50 10/07/99 50 10/07/99 1/14 Irritation Site Of Application
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Medium 1
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 11
85 11/11/99 92 11/18/99 2/14 Papilloma Site Of Application Medium 2
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 7
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 14
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: TPA PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
- CONTINUATION OF PREVIOUS ANIMAL DATA -
525 525 78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 9
REMOVED ** CID 525 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
526 526 85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Medium 1
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 12
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 16
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Medium 2
57 10/14/99 57 10/14/99 1/14 Papilloma Site Of Application Small 2
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
64 10/21/99 64 10/21/99 1/14 Papilloma Site Of Application Small 3
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 7
REMOVED ** CID 526 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
96 11/22/99 Papilloma Site Of Application Medium 2
527 527 71 10/28/99 71 10/28/99 1/12 Papilloma Site Of Application Small 18
78 11/04/99 78 11/04/99 1/12 Papilloma Site Of Application Small 20
64 10/21/99 64 10/21/99 1/12 Papilloma Site Of Application Small 9
REMOVED ** CID 527 ** REASON - Other
79 11/05/99 Papilloma Site Of Application Small 20
528 528 78 11/04/99 78 11/04/99 1/12 Papilloma Site Of Application Medium 1
71 10/28/99 78 11/04/99 2/12 Papilloma Site Of Application Small 11
64 10/21/99 64 10/21/99 1/12 Papilloma Site Of Application Small 6
REMOVED ** CID 528 ** REASON - NATD
83 11/09/99 Papilloma Site Of Application Small 7
83 11/09/99 Papilloma Site Of Application Medium 2
83 11/09/99 Papilloma Site Of Application Large 6
529 529 64 10/21/99 64 10/21/99 1/10 Papilloma Site Of Application Small 8
REMOVED ** CID 529 ** REASON - NATD
71 10/28/99 Papilloma Site Of Application Small 7
530 530 50 10/07/99 50 10/07/99 1/8 Irritation Site Of Application
REMOVED ** CID 530 ** REASON - NATD
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 15
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: TPA PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
- CONTINUATION OF PREVIOUS REMOVAL DATA -
530 530 54 10/11/99 Unremarkable
531 531 113 12/09/99 120 12/16/99 2/19 Papilloma Site Of Application Medium 10
92 11/18/99 92 11/18/99 1/19 Papilloma Site Of Application Small 12
99 11/25/99 99 11/25/99 1/19 Papilloma Site Of Application Medium 12
106 12/02/99 106 12/02/99 1/19 Papilloma Site Of Application Medium 13
127 12/23/99 127 12/23/99 1/19 Papilloma Site Of Application Medium 20
85 11/11/99 92 11/18/99 2/19 Papilloma Site Of Application Medium 3
99 11/25/99 106 12/02/99 2/19 Papilloma Site Of Application Small 3
64 10/21/99 64 10/21/99 1/19 Papilloma Site Of Application Small 4
113 12/09/99 120 12/16/99 2/19 Papilloma Site Of Application Large 6
71 10/28/99 120 12/16/99 3/19 Papilloma Site Of Application Small 7
78 11/04/99 78 11/04/99 1/19 Papilloma Site Of Application Small 8
85 11/11/99 85 11/11/99 1/19 Papilloma Site Of Application Small 9
REMOVED ** CID 531 ** REASON - Other
131 12/27/99 Papilloma Site Of Application Small 20
532 532 71 10/28/99 78 11/04/99 2/17 Irritation Site Of Application
106 12/02/99 106 12/02/99 1/17 Papilloma Site Of Application Medium 1
99 11/25/99 106 12/02/99 2/17 Papilloma Site Of Application Small 11
113 12/09/99 113 12/09/99 1/17 Papilloma Site Of Application Small 20
REMOVED ** CID 532 ** REASON - Other
118 12/14/99 Papilloma Site Of Application Small 20
533 533 50 10/07/99 50 10/07/99 1/14 Irritation Site Of Application
78 11/04/99 92 11/18/99 3/14 Papilloma Site Of Application Medium 1
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 10
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Small 15
92 11/18/99 92 11/18/99 1/14 Papilloma Site Of Application Small 20
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 8
REMOVED ** CID 533 ** REASON - Other
96 11/22/99 Papilloma Site Of Application Small 20
534 534 50 10/07/99 50 10/07/99 1/14 Irritation Site Of Application
71 10/28/99 71 10/28/99 1/14 Papilloma Site Of Application Small 13
78 11/04/99 78 11/04/99 1/14 Papilloma Site Of Application Small 18
85 11/11/99 85 11/11/99 1/14 Papilloma Site Of Application Medium 2
85 11/11/99 92 11/18/99 2/14 Papilloma Site Of Application Small 20
REMOVED ** CID 534 ** REASON - Other
NTP EXP/TEST: 97013-06 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 16
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/11/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 08:51:32
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: TPA PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
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- CONTINUATION OF PREVIOUS REMOVAL DATA -
534 534 96 11/22/99 Papilloma Site Of Application Small 20
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