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NICEATM: Alternative Methods

The NTP website, including all pages describing NICEATM and ICCVAM activities, will be unavailable starting 2:00 p.m. Friday, February 15 due to scheduled maintenance. The outage is scheduled to last until 8:30 a.m. on Wednesday, February 20, but some resources may not be restored until Thursday, February 21.

NICEATM Resources

Circular diagram of utilization, confidence, and technology

U.S. Roadmap

The U.S. Roadmap guides stakeholders seeking to develop or promote use of novel approaches to assessment. Learn more about this resource. Go
Closeup of well microplate for bioassay

Accepted Alternative Methods

NICEATM has compiled a list of alternative methods already accepted by U.S. agencies. Read more. Go
ICCVAM co-chairs Anna Lowit and Emily Reinke at SACATM 2018


View information on ICCVAM, a permanent committee of the NIEHS under NICEATM. Go
Closeup of test tubes

Test Method Evaluations

ICCVAM and NICEATM have evaluated approaches for replacing and reducing animal use, and ICCVAM has issued recommendations. Read more. Go
Diagram of integrated approaches process

Integrated Approaches to Testing & Assessment (IATAs)

IATAs enable all available information about a substance to inform a decision about the risk it may pose. Learn more about IATAs. Go
Robotic arm used for Tox21 testing

Tox21 Support

View information on NICEATM's support for the multiagency Tox21 research initiative. Go
Three scientists at a NICEATM event

3Rs Meetings & Workshops

NICEATM organizes meetings and workshops related to the 3Rs. Browse lists of events organized by NICEATM and collaborators. Go
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Publications & Presentations

View lists of NICEATM publications and presentations at scientific meetings. Go
Two female and one male scientists reviewing data on a laptop

Resources for Test Method Developers

Access resources for test method developers interested in alternative methods. Go
Judge's gavel next to set of glass test tubes

Testing Regulations & Guidelines

NICEATM has compiled a list of testing regulations and guidelines related to NICEATM and ICCVAM test method evaluations. Find out more. Go
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Contact NICEATM. Go