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TDMS Study 89029-06 Pathology Tables

NTP                                        STATISTICAL ANALYSIS OF PRIMARY TUMORS                              REPORT: PEIRPT08
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/06/98

EXPERIMENT: 89029 TEST: 06                                                                                     TIME: 08:58:27
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029
PATHOLOGIST: PLETCHER, J                                                                                       CAS: ELECTROMAG
            

Mice(B6C3F1)
-----------------------------
FOR ALL DOSES THE TUMOR RATES IN THE FOLLOWING TISSUES/ORGANS ARE BASED ON NUMBER OF TISSUES EXAMINED.
IN OTHER TISSUES/ORGANS, RATES ARE BASED ON NUMBER OF ANIMALS NECROPSIED.

                                                 ----------------
                                                 Adrenal Gland
                                                 Adrenal Medulla
                                                 Bone Marrow
                                                 Brain
                                                 Clitoral Gland
                                                 Clitoral/Preputial Gland
                                                 Epididymis
                                                 Heart
                                                 Islets, Pancreatic
                                                 Kidney
                                                 Liver
                                                 Lung
                                                 Nose
                                                 Ovary
                                                 Pancreas
                                                 Parathyroid Gland
                                                 Pituitary Gland
                                                 Preputial Gland
                                                 Prostate
                                                 Salivary Glands
                                                 Spleen
                                                 Testes
                                                 Thymus
                                                 Thyroid Gland
                                                 Urinary Bladder
NTP                                        STATISTICAL ANALYSIS OF PRIMARY TUMORS                              REPORT: PEIRPT08   
LAB: I. I. T. Research Inst                               MAGNETIC FIELDS (EMF)                                DATE: 01/06/98     
EXPERIMENT: 89029 TEST: 06                                                                                     TIME: 08:58:27     
TEST TYPE:  CHRONIC                             CAGES FROM 0000 TO LAST CAGE                                   PAGE:              
CONT: NO1-ES-25351                              ROUTE: MAGNETIC FIELDS                                         NTP C#: C89029     
PATHOLOGIST: PLETCHER, J                                                                                       CAS: ELECTROMAG    



SUMMARY OF STATISTICALLY SIGNIFICANT (P<=.05) RESULTS
IN THE ANALYSIS OF               MAGNETIC FIELDS (EMF)
===============================================================

Male Mice
------------
Organ                                 Morphology
-----                                 ----------
Adrenal Cortex                         Adenoma
Lung                                   Alveolar/Bronchiolar Adenoma
                                       Alveolar/Bronchiolar Carcinoma or Alveolar/Bronchiolar Adenoma
All Organs                             Malignant Tumors
===============================================================
Female Mice
------------
Organ                                  Morphology
-----                                  ----------
Lung                                   Alveolar/Bronchiolar Adenoma
                                       Alveolar/Bronchiolar Carcinoma or Alveolar/Bronchiolar Adenoma
All Organs                             Malignant Lymphoma: Histiocytic, Lymphocytic, Mixed, NOS, or Undifferentiated Cell Type
                                       Malignant Tumors
===============================================================
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 1
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)        -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Cortex                                                                                                                   |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     3/99 (3%)    0/96 (0%)    1/99 (1%)    5/94 (5%)   |0/92 (0%)    0/98 (0%)    2/99 (2%)    0/99 (0%)    |
|POLY-3 ADJUSTED (b)|     3.3%         0.0%         1.1%         6.1%        |0.0%         0.0%         2.2%         0.0%         |
|TERMINAL (d)       |     3/76 (4%)    0/71 (0%)    1/84 (1%)    5/61 (8%)   |0/70 (0%)    0/74 (0%)    2/79 (3%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      ---          734 (T)      734 (T)     |---          ---          735 (T)      ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.018 *    P=0.135N     P=0.272N     P=0.247     |P=0.631N     (e)          P=0.266      (e)          |
|POLY 3             |     P=0.032 *    P=0.134N     P=0.305N     P=0.297     |P=0.634N     (e)          P=0.250      (e)          |
|POLY 1.5           |     P=0.034 *    P=0.131N     P=0.306N     P=0.311     |P=0.632N     (e)          P=0.251      (e)          |
|POLY 6             |     P=0.031 *    P=0.137N     P=0.302N     P=0.283     |P=0.634N     (e)          P=0.247      (e)          |
|LOGISTIC REGRESSION|     P=0.018 *    (e)          P=0.272N     P=0.247     |(e)          (e)          P=0.266      (e)          |
|COCH-ARM / FISHERS |     P=0.037 *    P=0.129N     P=0.311N     P=0.332     |P=0.625N     (e)          P=0.267      (e)          |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma Benign                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/98 (1%)    0/93 (0%)    1/99 (1%)    0/91 (0%)   |0/90 (0%)    3/95 (3%)    1/97 (1%)    2/97 (2%)    |
|POLY-3 ADJUSTED (b)|     1.1%         0.0%         1.1%         0.0%        |0.0%         3.5%         1.1%         2.3%         |
|TERMINAL (d)       |     1/76 (1%)    0/68 (0%)    1/84 (1%)    0/61 (0%)   |0/70 (0%)    3/73 (4%)    1/79 (1%)    2/73 (3%)    |
|FIRST INCIDENCE    |     734 (T)      ---          734 (T)      ---         |---          735 (T)      735 (T)      735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.544N     P=0.522N     P=0.739N     P=0.544N    |P=0.501      P=0.130      P=0.524      P=0.248      |
|POLY 3             |     P=0.518N     P=0.519N     P=0.757N     P=0.527N    |P=0.498      P=0.124      P=0.512      P=0.245      |
|POLY 1.5           |     P=0.516N     P=0.515N     P=0.758N     P=0.522N    |P=0.502      P=0.126      P=0.513      P=0.247      |
|POLY 6             |     P=0.520N     P=0.523N     P=0.756N     P=0.532N    |P=0.495      P=0.123      P=0.510      P=0.243      |
|LOGISTIC REGRESSION|     P=0.544N     (e)          P=0.739N     (e)         |(e)          P=0.130      P=0.524      P=0.248      |
|COCH-ARM / FISHERS |     P=0.512N     P=0.513N     P=0.749N     P=0.519N    |P=0.516      P=0.133      P=0.519      P=0.268      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 2
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Adrenal Medulla                                                                                                                  |
|     Pheochromocytoma: Benign, Complex, Malignant, NOS                                                                           |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     2/98 (2%)    0/93 (0%)    1/99 (1%)    0/91 (0%)   |0/90 (0%)    3/95 (3%)    1/97 (1%)    2/97 (2%)    |
|POLY-3 ADJUSTED (b)|     2.2%         0.0%         1.1%         0.0%        |0.0%         3.5%         1.1%         2.3%         |
|TERMINAL (d)       |     2/76 (3%)    0/68 (0%)    1/84 (1%)    0/61 (0%)   |0/70 (0%)    3/73 (4%)    1/79 (1%)    2/73 (3%)    |
|FIRST INCIDENCE    |     734 (T)      ---          734 (T)      ---         |---          735 (T)      735 (T)      735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.377N     P=0.264N     P=0.465N     P=0.289N    |P=0.501      P=0.130      P=0.524      P=0.248      |
|POLY 3             |     P=0.353N     P=0.260N     P=0.495N     P=0.269N    |P=0.498      P=0.124      P=0.512      P=0.245      |
|POLY 1.5           |     P=0.351N     P=0.256N     P=0.496N     P=0.264N    |P=0.502      P=0.126      P=0.513      P=0.247      |
|POLY 6             |     P=0.354N     P=0.264N     P=0.493N     P=0.275N    |P=0.495      P=0.123      P=0.510      P=0.243      |
|LOGISTIC REGRESSION|     P=0.377N     (e)          P=0.465N     (e)         |(e)          P=0.130      P=0.524      P=0.248      |
|COCH-ARM / FISHERS |     P=0.348N     P=0.262N     P=0.496N     P=0.268N    |P=0.516      P=0.133      P=0.519      P=0.268      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Brain                                                                                                                            |
|     Hamartoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/99 (0%)    0/100 (0%)   0/99 (0%)   |0/99 (0%)    1/100 (1%)   2/98 (2%)    0/98 (0%)    |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |0.0%         1.1%         2.2%         0.0%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    2/79 (3%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |---          64           735 (T)      ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.441N     P=0.500      P=0.266      (e)          |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.451N     P=0.503      P=0.240      (e)          |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.452N     P=0.503      P=0.238      (e)          |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.449N     P=0.503      P=0.240      (e)          |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.391N     (e)          P=0.266      (e)          |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.448N     P=0.503      P=0.246      (e)          |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 3
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Harderian Gland                                                                                                                  |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     12/100 (12%) 16/100 (16%) 16/100 (16%) 12/100 (12%)|10/100 (10%) 8/100 (8%)   14/100 (14%) 12/100 (12%) |
|POLY-3 ADJUSTED (b)|     13.0%        17.8%        16.9%        13.9%       |11.0%        8.8%         15.3%        13.4%        |
|TERMINAL (d)       |     11/76 (15%)  12/72 (17%)  11/84 (13%)  9/62 (15%)  |7/70 (10%)   6/74 (8%)    13/79 (17%)  12/74 (16%)  |
|FIRST INCIDENCE    |     716          589          585          483         |625          692          692          735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.555      P=0.226      P=0.362      P=0.392     |P=0.333      P=0.367N     P=0.350      P=0.458      |
|POLY 3             |     P=0.413N     P=0.240      P=0.290      P=0.517     |P=0.309      P=0.406N     P=0.258      P=0.399      |
|POLY 1.5           |     P=0.383N     P=0.252      P=0.281      P=0.544     |P=0.310      P=0.406N     P=0.255      P=0.399      |
|POLY 6             |     P=0.449N     P=0.229      P=0.306      P=0.486     |P=0.310      P=0.408N     P=0.256      P=0.399      |
|LOGISTIC REGRESSION|     P=0.401N     P=0.220      P=0.274      P=0.486     |P=0.321      P=0.402N     P=0.263      P=0.410      |
|COCH-ARM / FISHERS |     P=0.338N     P=0.271      P=0.271      P=0.586N    |P=0.322      P=0.403N     P=0.257      P=0.411      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Harderian Gland                                                                                                                  |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     12/100 (12%) 18/100 (18%) 16/100 (16%) 12/100 (12%)|12/100 (12%) 8/100 (8%)   14/100 (14%) 12/100 (12%) |
|POLY-3 ADJUSTED (b)|     13.0%        19.9%        16.9%        13.9%       |13.2%        8.8%         15.3%        13.4%        |
|TERMINAL (d)       |     11/76 (15%)  13/72 (18%)  11/84 (13%)  9/62 (15%)  |9/70 (13%)   6/74 (8%)    13/79 (17%)  12/74 (16%)  |
|FIRST INCIDENCE    |     716          485          585          483         |625          692          692          735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.480N     P=0.130      P=0.362      P=0.392     |P=0.424      P=0.211N     P=0.528      P=0.536N     |
|POLY 3             |     P=0.342N     P=0.142      P=0.290      P=0.517     |P=0.398      P=0.242N     P=0.419      P=0.574      |
|POLY 1.5           |     P=0.312N     P=0.149      P=0.281      P=0.544     |P=0.398      P=0.242N     P=0.415      P=0.574      |
|POLY 6             |     P=0.378N     P=0.135      P=0.306      P=0.486     |P=0.399      P=0.243N     P=0.418      P=0.575      |
|LOGISTIC REGRESSION|     P=0.309N     P=0.138      P=0.274      P=0.486     |P=0.411      P=0.239N     P=0.425      P=0.586N     |
|COCH-ARM / FISHERS |     P=0.268N     P=0.161      P=0.271      P=0.586N    |P=0.411      P=0.240N     P=0.417      P=0.586N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 4
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Heart                                                                                                                            |
|     Hemangiosarcoma                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   2/100 (2%)   0/100 (0%)   0/99 (0%)   |0/98 (0%)    0/100 (0%)   0/100 (0%)   0/99 (0%)    |
|POLY-3 ADJUSTED (b)|     0.0%         2.3%         0.0%         0.0%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     0/76 (0%)    2/72 (3%)    0/84 (0%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          734 (T)      ---          ---         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.404N     P=0.227      (e)          (e)         |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.385N     P=0.229      (e)          (e)         |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.379N     P=0.233      (e)          (e)         |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.393N     P=0.225      (e)          (e)         |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     (e)          P=0.227      (e)          (e)         |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.369N     P=0.249      (e)          (e)         |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small: Duodenum                                                                                                        |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   2/100 (2%)   1/100 (1%)   0/100 (0%)  |0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     0.0%         2.3%         1.1%         0.0%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     0/76 (0%)    1/72 (1%)    1/84 (1%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          725          734 (T)      ---         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.380N     P=0.228      P=0.520      (e)         |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.359N     P=0.229      P=0.501      (e)         |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.351N     P=0.233      P=0.501      (e)         |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.369N     P=0.226      P=0.503      (e)         |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.365N     P=0.223      P=0.520      (e)         |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.338N     P=0.249      P=0.500      (e)         |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 5
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small: Jejunum                                                                                                         |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/100 (1%)   1/100 (1%)   3/100 (3%)   1/100 (1%)  |0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     1.1%         1.1%         3.2%         1.2%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    1/72 (1%)    3/84 (4%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      734 (T)      734 (T)      500         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.649N     P=0.749      P=0.343      P=0.733     |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.602N     P=0.751      P=0.309      P=0.745     |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.593N     P=0.755      P=0.308      P=0.751     |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.612N     P=0.747      P=0.312      P=0.738     |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.568N     P=0.749      P=0.343      P=0.694N    |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.579N     P=0.751N     P=0.311      P=0.751N    |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Intestine Small: Site Unspecified                                                                                                |
|     Carcinoma                                                                                                                   |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/100 (1%)   3/100 (3%)   4/100 (4%)   2/100 (2%)  |0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     1.1%         3.4%         4.3%         2.3%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    2/72 (3%)    4/84 (5%)    1/62 (2%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      725          734 (T)      500         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.600      P=0.289      P=0.214      P=0.448     |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.595N     P=0.292      P=0.184      P=0.476     |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.582N     P=0.298      P=0.183      P=0.485     |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.610N     P=0.286      P=0.187      P=0.465     |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.578N     P=0.282      P=0.214      P=0.562     |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.562N     P=0.311      P=0.184      P=0.500     |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 6
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/99 (1%)    3/99 (3%)    1/98 (1%)    0/97 (0%)   |2/87 (2%)    0/95 (0%)    7/94 (7%)    2/94 (2%)    |
|POLY-3 ADJUSTED (b)|     1.1%         3.4%         1.1%         0.0%        |2.4%         0.0%         8.0%         2.3%         |
|TERMINAL (d)       |     1/76 (1%)    2/72 (3%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    0/74 (0%)    6/79 (8%)    2/74 (3%)    |
|FIRST INCIDENCE    |     734 (T)      722          585          ---         |542          ---          694          735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.192N     P=0.290      P=0.749N     P=0.541N    |P=0.594      P=0.236N     P=0.111      P=0.680N     |
|POLY 3             |     P=0.181N     P=0.292      P=0.759N     P=0.517N    |P=0.609      P=0.228N     P=0.101      P=0.672N     |
|POLY 1.5           |     P=0.176N     P=0.298      P=0.760      P=0.512N    |P=0.608      P=0.225N     P=0.102      P=0.670N     |
|POLY 6             |     P=0.188N     P=0.286      P=0.756N     P=0.523N    |P=0.610      P=0.230N     P=0.098      P=0.675N     |
|LOGISTIC REGRESSION|     P=0.165N     P=0.282      P=0.757      (e)         |P=0.605      P=0.185N     P=0.106      P=0.655N     |
|COCH-ARM / FISHERS |     P=0.167N     P=0.311      P=0.749      P=0.505N    |P=0.605      P=0.227N     P=0.104      P=0.660N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Islets, Pancreatic                                                                                                               |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     3/99 (3%)    3/99 (3%)    2/98 (2%)    1/97 (1%)   |2/87 (2%)    0/95 (0%)    7/94 (7%)    2/94 (2%)    |
|POLY-3 ADJUSTED (b)|     3.2%         3.4%         2.2%         1.2%        |2.4%         0.0%         8.0%         2.3%         |
|TERMINAL (d)       |     2/76 (3%)    2/72 (3%)    1/84 (1%)    1/62 (2%)   |1/70 (1%)    0/74 (0%)    6/79 (8%)    2/74 (3%)    |
|FIRST INCIDENCE    |     534          722          585          734 (T)     |542          ---          694          735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.288N     P=0.638      P=0.473N     P=0.371N    |P=0.594      P=0.236N     P=0.111      P=0.680N     |
|POLY 3             |     P=0.258N     P=0.638      P=0.501N     P=0.340N    |P=0.609      P=0.228N     P=0.101      P=0.672N     |
|POLY 1.5           |     P=0.250N     P=0.647      P=0.503N     P=0.329N    |P=0.608      P=0.225N     P=0.102      P=0.670N     |
|POLY 6             |     P=0.268N     P=0.629      P=0.496N     P=0.352N    |P=0.610      P=0.230N     P=0.098      P=0.675N     |
|LOGISTIC REGRESSION|     P=0.227N     P=0.653N     P=0.510N     P=0.287N    |P=0.605      P=0.185N     P=0.106      P=0.655N     |
|COCH-ARM / FISHERS |     P=0.238N     P=0.659N     P=0.505N     P=0.318N    |P=0.605      P=0.227N     P=0.104      P=0.660N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 7
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Renal Tubule                                                                                                             |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/99 (1%)    2/98 (2%)    0/99 (0%)    0/96 (0%)   |0/92 (0%)    0/96 (0%)    0/98 (0%)    0/98 (0%)    |
|POLY-3 ADJUSTED (b)|     1.1%         2.3%         0.0%         0.0%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    2/72 (3%)    0/84 (0%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      734 (T)      ---          ---         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.274N     P=0.481      P=0.480N     P=0.541N    |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.257N     P=0.484      P=0.499N     P=0.518N    |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.253N     P=0.489      P=0.500N     P=0.513N    |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.262N     P=0.478      P=0.497N     P=0.523N    |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.274N     P=0.481      (e)          (e)         |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.247N     P=0.496      P=0.500N     P=0.508N    |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Kidney: Renal Tubule                                                                                                             |
|     Carcinoma or Adenoma                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     2/99 (2%)    2/98 (2%)    0/99 (0%)    0/96 (0%)   |0/92 (0%)    0/96 (0%)    0/98 (0%)    0/98 (0%)    |
|POLY-3 ADJUSTED (b)|     2.2%         2.3%         0.0%         0.0%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    2/72 (3%)    0/84 (0%)    0/62 (0%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     534          734 (T)      ---          ---         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.189N     P=0.676      P=0.229N     P=0.272N    |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.177N     P=0.673      P=0.239N     P=0.260N    |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.174N     P=0.679      P=0.239N     P=0.254N    |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.181N     P=0.666      P=0.238N     P=0.268N    |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.160N     P=0.678N     P=0.237N     P=0.194N    |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.169N     P=0.686      P=0.249N     P=0.256N    |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 8
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hemangiosarcoma                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     4/100 (4%)   2/100 (2%)   3/100 (3%)   5/98 (5%)   |1/98 (1%)    1/97 (1%)    1/98 (1%)    0/99 (0%)    |
|POLY-3 ADJUSTED (b)|     4.3%         2.2%         3.2%         5.9%        |1.1%         1.1%         1.1%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    1/72 (1%)    1/84 (1%)    3/62 (5%)   |0/70 (0%)    1/74 (1%)    1/79 (1%)    0/74 (0%)    |
|FIRST INCIDENCE    |     582          624          585          518         |723          735 (T)      735 (T)      ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.187      P=0.369N     P=0.475N     P=0.407     |P=0.334N     P=0.753N     P=0.744N     P=0.497N     |
|POLY 3             |     P=0.222      P=0.361N     P=0.498N     P=0.446     |P=0.337N     P=0.758      P=0.759N     P=0.500N     |
|POLY 1.5           |     P=0.231      P=0.352N     P=0.499N     P=0.463     |P=0.337N     P=0.758      P=0.759N     P=0.500N     |
|POLY 6             |     P=0.212      P=0.371N     P=0.495N     P=0.426     |P=0.337N     P=0.758      P=0.759N     P=0.500N     |
|LOGISTIC REGRESSION|     P=0.291      P=0.300N     P=0.503N     P=0.552     |P=0.335N     P=0.760      P=0.760N     P=0.500N     |
|COCH-ARM / FISHERS |     P=0.244      P=0.341N     P=0.500N     P=0.487     |P=0.333N     P=0.749      P=0.751N     P=0.497N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatoblastoma                                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     2/100 (2%)   2/100 (2%)   1/100 (1%)   4/98 (4%)   |0/98 (0%)    0/97 (0%)    0/98 (0%)    0/99 (0%)    |
|POLY-3 ADJUSTED (b)|     2.2%         2.3%         1.1%         4.7%        |0.0%         0.0%         0.0%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    2/72 (3%)    1/84 (1%)    3/62 (5%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     731          734 (T)      734 (T)      716         |---          ---          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.116      P=0.672      P=0.467N     P=0.256     |(e)          (e)          (e)          (e)          |
|POLY 3             |     P=0.160      P=0.678      P=0.498N     P=0.300     |(e)          (e)          (e)          (e)          |
|POLY 1.5           |     P=0.167      P=0.684      P=0.499N     P=0.312     |(e)          (e)          (e)          (e)          |
|POLY 6             |     P=0.153      P=0.671      P=0.495N     P=0.286     |(e)          (e)          (e)          (e)          |
|LOGISTIC REGRESSION|     P=0.132      P=0.671      P=0.480N     P=0.269     |(e)          (e)          (e)          (e)          |
|COCH-ARM / FISHERS |     P=0.176      P=0.689N     P=0.500N     P=0.332     |(e)          (e)          (e)          (e)          |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 9
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatocellular Adenoma                                                                                                      |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     30/100 (30%) 26/100 (26%) 32/100 (32%) 21/98 (21%) |17/98 (17%)  10/97 (10%)  20/98 (20%)  18/99 (18%)  |
|POLY-3 ADJUSTED (b)|     32.3%        28.9%        34.0%        24.4%       |19.0%        11.3%        22.0%        20.1%        |
|TERMINAL (d)       |     28/76 (37%)  22/72 (31%)  30/84 (36%)  15/62 (24%) |16/70 (23%)  9/74 (12%)   19/79 (24%)  16/74 (22%)  |
|FIRST INCIDENCE    |     646          560          562          500         |667          723          578          690          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.318N     P=0.410N     P=0.508N     P=0.304N    |P=0.258      P=0.080N     P=0.508      P=0.569      |
|POLY 3             |     P=0.148N     P=0.367N     P=0.460      P=0.156N    |P=0.246      P=0.111N     P=0.371      P=0.498      |
|POLY 1.5           |     P=0.130N     P=0.347N     P=0.450      P=0.136N    |P=0.248      P=0.112N     P=0.367      P=0.498      |
|POLY 6             |     P=0.174N     P=0.388N     P=0.479      P=0.181N    |P=0.248      P=0.110N     P=0.369      P=0.501      |
|LOGISTIC REGRESSION|     P=0.171N     P=0.411N     P=0.461      P=0.191N    |P=0.251      P=0.104N     P=0.363      P=0.511      |
|COCH-ARM / FISHERS |     P=0.108N     P=0.318N     P=0.439      P=0.112N    |P=0.264      P=0.112N     P=0.358      P=0.513      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatocellular Carcinoma                                                                                                    |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     19/100 (19%) 14/100 (14%) 20/100 (20%) 15/98 (15%) |6/98 (6%)    5/97 (5%)    7/98 (7%)    6/99 (6%)    |
|POLY-3 ADJUSTED (b)|     19.8%        15.3%        21.2%        17.1%       |6.7%         5.6%         7.7%         6.6%         |
|TERMINAL (d)       |     8/76 (11%)   6/72 (8%)    17/84 (20%)  9/62 (15%)  |4/70 (6%)    2/74 (3%)    5/79 (6%)    4/74 (5%)    |
|FIRST INCIDENCE    |     520          542          527          480         |691          545          578          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.519      P=0.296N     P=0.546N     P=0.473N    |P=0.546      P=0.482N     P=0.561      P=0.592N     |
|POLY 3             |     P=0.472N     P=0.268N     P=0.477      P=0.392N    |P=0.554      P=0.502N     P=0.511      P=0.607N     |
|POLY 1.5           |     P=0.442N     P=0.250N     P=0.486      P=0.356N    |P=0.553      P=0.505N     P=0.507      P=0.609N     |
|POLY 6             |     P=0.513N     P=0.289N     P=0.468      P=0.438N    |P=0.554      P=0.499N     P=0.512      P=0.605N     |
|LOGISTIC REGRESSION|     P=0.321N     P=0.150N     P=0.495      P=0.191N    |P=0.574      P=0.507N     P=0.501      P=0.581N     |
|COCH-ARM / FISHERS |     P=0.402N     P=0.223N     P=0.500      P=0.309N    |P=0.553      P=0.507N     P=0.500      P=0.609N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 10
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatocellular Carcinoma or Hepatoblastoma                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     21/100 (21%) 16/100 (16%) 21/100 (21%) 19/98 (19%) |6/98 (6%)    5/97 (5%)    7/98 (7%)    6/99 (6%)    |
|POLY-3 ADJUSTED (b)|     21.9%        17.5%        22.2%        21.7%       |6.7%         5.6%         7.7%         6.6%         |
|TERMINAL (d)       |     9/76 (12%)   8/72 (11%)   18/84 (21%)  12/62 (19%) |4/70 (6%)    2/74 (3%)    5/79 (6%)    4/74 (5%)    |
|FIRST INCIDENCE    |     520          542          527          480         |691          545          578          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.310      P=0.312N     P=0.470N     P=0.487     |P=0.546      P=0.482N     P=0.561      P=0.592N     |
|POLY 3             |     P=0.428      P=0.283N     P=0.545      P=0.557N    |P=0.554      P=0.502N     P=0.511      P=0.607N     |
|POLY 1.5           |     P=0.460      P=0.262N     P=0.554      P=0.516N    |P=0.553      P=0.505N     P=0.507      P=0.609N     |
|POLY 6             |     P=0.386      P=0.306N     P=0.536      P=0.534     |P=0.554      P=0.499N     P=0.512      P=0.605N     |
|LOGISTIC REGRESSION|     P=0.529N     P=0.170N     P=0.565      P=0.353N    |P=0.574      P=0.507N     P=0.501      P=0.581N     |
|COCH-ARM / FISHERS |     P=0.504      P=0.233N     P=0.569N     P=0.458N    |P=0.553      P=0.507N     P=0.500      P=0.609N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatocellular Carcinoma or Hepatocellular Adenoma                                                                          |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     46/100 (46%) 37/100 (37%) 45/100 (45%) 35/98 (36%) |22/98 (22%)  13/97 (13%)  24/98 (24%)  23/99 (23%)  |
|POLY-3 ADJUSTED (b)|     47.8%        39.9%        47.2%        39.5%       |24.5%        14.5%        26.4%        25.2%        |
|TERMINAL (d)       |     34/76 (45%)  26/72 (36%)  40/84 (48%)  24/62 (39%) |19/70 (27%)  10/74 (14%)  22/79 (28%)  19/74 (26%)  |
|FIRST INCIDENCE    |     520          542          527          480         |667          545          578          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.502N     P=0.231N     P=0.310N     P=0.354N    |P=0.215      P=0.052N     P=0.537N     P=0.563N     |
|POLY 3             |     P=0.242N     P=0.169N     P=0.522N     P=0.157N    |P=0.217      P=0.067N     P=0.451      P=0.522      |
|POLY 1.5           |     P=0.205N     P=0.150N     P=0.513N     P=0.126N    |P=0.216      P=0.069N     P=0.445      P=0.518      |
|POLY 6             |     P=0.297N     P=0.190N     P=0.528N     P=0.204N    |P=0.217      P=0.065N     P=0.448      P=0.526      |
|LOGISTIC REGRESSION|     P=0.187N     P=0.129N     P=0.498N     P=0.103N    |P=0.206      P=0.071N     P=0.443      P=0.504      |
|COCH-ARM / FISHERS |     P=0.164N     P=0.125N     P=0.500N     P=0.092N    |P=0.219      P=0.072N     P=0.433      P=0.516      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 11
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Liver                                                                                                                            |
|     Hepatocellular Carcinoma, Hepatocellular Adenoma,                                                                           |
|     or Hepatoblastoma                                                                                                           |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     47/100 (47%) 38/100 (38%) 46/100 (46%) 38/98 (39%) |22/98 (22%)  13/97 (13%)  24/98 (24%)  23/99 (23%)  |
|POLY-3 ADJUSTED (b)|     48.8%        41.0%        48.2%        42.8%       |24.5%        14.5%        26.4%        25.2%        |
|TERMINAL (d)       |     34/76 (45%)  27/72 (38%)  41/84 (49%)  26/62 (42%) |19/70 (27%)  10/74 (14%)  22/79 (28%)  19/74 (26%)  |
|FIRST INCIDENCE    |     520          542          527          480         |667          545          578          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.424      P=0.235N     P=0.307N     P=0.478N    |P=0.215      P=0.052N     P=0.537N     P=0.563N     |
|POLY 3             |     P=0.371N     P=0.171N     P=0.522N     P=0.247N    |P=0.217      P=0.067N     P=0.451      P=0.522      |
|POLY 1.5           |     P=0.324N     P=0.152N     P=0.514N     P=0.203N    |P=0.216      P=0.069N     P=0.445      P=0.518      |
|POLY 6             |     P=0.437N     P=0.193N     P=0.529N     P=0.310N    |P=0.217      P=0.065N     P=0.448      P=0.526      |
|LOGISTIC REGRESSION|     P=0.305N     P=0.133N     P=0.497N     P=0.177N    |P=0.206      P=0.071N     P=0.443      P=0.504      |
|COCH-ARM / FISHERS |     P=0.267N     P=0.126N     P=0.500N     P=0.153N    |P=0.219      P=0.072N     P=0.433      P=0.516      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Alveolar/Bronchiolar Adenoma                                                                                                |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     26/100 (26%) 11/99 (11%)  9/100 (9%)   16/99 (16%) |9/95 (9%)    6/100 (6%)   0/99 (0%)    5/99 (5%)    |
|POLY-3 ADJUSTED (b)|     28.0%        12.5%        9.6%         18.0%       |10.2%        6.6%         0.0%         5.6%         |
|TERMINAL (d)       |     22/76 (29%)  10/72 (14%)  7/84 (8%)    7/62 (11%)  |7/70 (10%)   4/74 (5%)    0/79 (0%)    4/74 (5%)    |
|FIRST INCIDENCE    |     683          722          585          518         |551          603          ---          566          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.430      P=0.009N**   P<0.001N**   P=0.187N    |P=0.363N     P=0.270N     P=0.002N**   P=0.181N     |
|POLY 3             |     P=0.470N     P=0.007N**   P<0.001N**   P=0.077N    |P=0.363N     P=0.271N     P=0.002N**   P=0.190N     |
|POLY 1.5           |     P=0.464N     P=0.006N**   P<0.001N**   P=0.071N    |P=0.365N     P=0.269N     P=0.002N**   P=0.190N     |
|POLY 6             |     P=0.475N     P=0.009N**   P<0.001N**   P=0.084N    |P=0.360N     P=0.274N     P=0.002N**   P=0.189N     |
|LOGISTIC REGRESSION|     P=0.500N     P=0.009N**   P<0.001N**   P=0.074N    |P=0.362N     P=0.264N     P=0.003N**   P=0.184N     |
|COCH-ARM / FISHERS |     P=0.454N     P=0.006N**   P<0.001N**   P=0.063N    |P=0.360N     P=0.261N     P<0.001N**   P=0.181N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 12
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Alveolar/Bronchiolar Carcinoma                                                                                              |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     8/100 (8%)   11/99 (11%)  12/100 (12%) 10/99 (10%) |2/95 (2%)    6/100 (6%)   2/99 (2%)    2/99 (2%)    |
|POLY-3 ADJUSTED (b)|     8.6%         12.4%        12.8%        11.5%       |2.3%         6.6%         2.2%         2.2%         |
|TERMINAL (d)       |     7/76 (9%)    9/72 (13%)   11/84 (13%)  5/62 (8%)   |0/70 (0%)    4/74 (5%)    2/79 (3%)    1/74 (1%)    |
|FIRST INCIDENCE    |     715          612          430          448         |701          496          735 (T)      687          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.359      P=0.272      P=0.313      P=0.267     |P=0.283N     P=0.152      P=0.671N     P=0.688N     |
|POLY 3             |     P=0.495      P=0.280      P=0.249      P=0.351     |P=0.287N     P=0.154      P=0.678N     P=0.684N     |
|POLY 1.5           |     P=0.514      P=0.290      P=0.246      P=0.369     |P=0.287N     P=0.154      P=0.678N     P=0.684N     |
|POLY 6             |     P=0.471      P=0.269      P=0.256      P=0.331     |P=0.286N     P=0.153      P=0.681N     P=0.684N     |
|LOGISTIC REGRESSION|     P=0.517      P=0.263      P=0.242      P=0.385     |P=0.275N     P=0.166      P=0.679N     P=0.682N     |
|COCH-ARM / FISHERS |     P=0.541      P=0.307      P=0.240      P=0.394     |P=0.280N     P=0.157      P=0.674N     P=0.674N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Lung                                                                                                                             |
|     Alveolar/Bronchiolar Carcinoma or Alveolar/Bronchiolar                                                                      |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     30/100 (30%) 21/99 (21%)  19/100 (19%) 25/99 (25%) |11/95 (12%)  11/100 (11%) 2/99 (2%)    7/99 (7%)    |
|POLY-3 ADJUSTED (b)|     32.2%        23.7%        20.1%        27.7%       |12.5%        11.9%        2.2%         7.8%         |
|TERMINAL (d)       |     25/76 (33%)  19/72 (26%)  16/84 (19%)  11/62 (18%) |7/70 (10%)   7/74 (10%)   2/79 (3%)    5/74 (7%)    |
|FIRST INCIDENCE    |     683          612          430          448         |551          496          735 (T)      566          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.232      P=0.144N     P=0.025N*    P=0.542N    |P=0.245N     P=0.553N     P=0.008N**   P=0.209N     |
|POLY 3             |     P=0.495      P=0.130N     P=0.041N*    P=0.302N    |P=0.246N     P=0.544N     P=0.008N**   P=0.213N     |
|POLY 1.5           |     P=0.497      P=0.119N     P=0.044N*    P=0.293N    |P=0.246N     P=0.544N     P=0.008N**   P=0.213N     |
|POLY 6             |     P=0.497      P=0.146N     P=0.037N*    P=0.310N    |P=0.243N     P=0.545N     P=0.009N**   P=0.213N     |
|LOGISTIC REGRESSION|     P=0.460      P=0.150N     P=0.047N*    P=0.291N    |P=0.237N     P=0.531N     P=0.009N**   P=0.207N     |
|COCH-ARM / FISHERS |     P=0.501      P=0.104N     P=0.050N     P=0.278N    |P=0.239N     P=0.539N     P=0.007N**   P=0.202N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 13
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Mesentery                                                                                                                        |
|     Liposarcoma                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)  |0/100 (0%)   3/100 (3%)   1/100 (1%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |0.0%         3.3%         1.1%         0.0%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |0/70 (0%)    3/74 (4%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |---          735 (T)      659          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.232N     P=0.132      P=0.495      (e)          |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.235N     P=0.121      P=0.502      (e)          |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.235N     P=0.121      P=0.501      (e)          |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.234N     P=0.121      P=0.503      (e)          |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.235N     P=0.132      P=0.507      (e)          |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.234N     P=0.123      P=0.500      (e)          |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Cystadenoma                                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |3/79 (4%)    3/91 (3%)    2/95 (2%)    2/94 (2%)    |
|POLY-3 ADJUSTED (b)|                                                        |4.0%         3.6%         2.3%         2.4%         |
|TERMINAL (d)       |                                                        |3/65 (5%)    2/70 (3%)    2/78 (3%)    2/72 (3%)    |
|FIRST INCIDENCE    |                                                        |735 (T)      461          735 (T)      735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |P=0.418N     P=0.630N     P=0.418N     P=0.454N     |
|POLY 3             |                                                        |P=0.407N     P=0.605N     P=0.424N     P=0.439N     |
|POLY 1.5           |                                                        |P=0.405N     P=0.602N     P=0.422N     P=0.435N     |
|POLY 6             |                                                        |P=0.407N     P=0.609N     P=0.430N     P=0.442N     |
|LOGISTIC REGRESSION|                                                        |P=0.396N     P=0.581N     P=0.418N     P=0.454N     |
|COCH-ARM / FISHERS |                                                        |P=0.395N     P=0.590N     P=0.413N     P=0.418N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 14
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Ovary                                                                                                                            |
|     Granulosa Cell Tumor Benign                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |                                                        |2/79 (3%)    3/91 (3%)    1/95 (1%)    0/94 (0%)    |
|POLY-3 ADJUSTED (b)|                                                        |2.7%         3.6%         1.1%         0.0%         |
|TERMINAL (d)       |                                                        |2/65 (3%)    3/70 (4%)    1/78 (1%)    0/72 (0%)    |
|FIRST INCIDENCE    |                                                        |735 (T)      735 (T)      735 (T)      ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |                                                        |P=0.107N     P=0.534      P=0.437N     P=0.217N     |
|POLY 3             |                                                        |P=0.106N     P=0.550      P=0.442N     P=0.208N     |
|POLY 1.5           |                                                        |P=0.105N     P=0.554      P=0.440N     P=0.207N     |
|POLY 6             |                                                        |P=0.106N     P=0.545      P=0.446N     P=0.210N     |
|LOGISTIC REGRESSION|                                                        |P=0.107N     P=0.534      P=0.437N     (e)          |
|COCH-ARM / FISHERS |                                                        |P=0.102N     P=0.567      P=0.431N     P=0.207N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Pituitary Gland: Pars Distalis or Unspecified Site                                                                               |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/83 (0%)    1/84 (1%)    1/82 (1%)    0/84 (0%)   |17/83 (20%)  17/92 (18%)  20/87 (23%)  21/89 (24%)  |
|POLY-3 ADJUSTED (b)|     0.0%         1.3%         1.3%         0.0%        |21.9%        20.1%        24.1%        25.8%        |
|TERMINAL (d)       |     0/66 (0%)    1/64 (2%)    0/72 (0%)    0/57 (0%)   |16/67 (24%)  15/71 (21%)  20/76 (26%)  20/71 (28%)  |
|FIRST INCIDENCE    |     ---          734 (T)      701          ---         |625          698          735 (T)      730          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.534N     P=0.494      P=0.509      (e)         |P=0.269      P=0.508N     P=0.520      P=0.360      |
|POLY 3             |     P=0.515N     P=0.494      P=0.500      (e)         |P=0.258      P=0.465N     P=0.445      P=0.352      |
|POLY 1.5           |     P=0.508N     P=0.497      P=0.499      (e)         |P=0.261      P=0.460N     P=0.437      P=0.356      |
|POLY 6             |     P=0.522N     P=0.491      P=0.502      (e)         |P=0.253      P=0.470N     P=0.448      P=0.346      |
|LOGISTIC REGRESSION|     P=0.507N     P=0.494      P=0.496      (e)         |P=0.259      P=0.467N     P=0.463      P=0.356      |
|COCH-ARM / FISHERS |     P=0.499N     P=0.503      P=0.497      (e)         |P=0.279      P=0.442N     P=0.417      P=0.380      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 15
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skeletal Muscle                                                                                                                  |
|     Rhabdomyosarcoma                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   0/100 (0%)   1/100 (1%)  |3/100 (3%)   1/100 (1%)   0/100 (0%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         1.2%        |3.3%         1.1%         0.0%         0.0%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |2/70 (3%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          703         |707          713          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.210      (e)          (e)          P=0.472     |P=0.163N     P=0.296N     P=0.110N     P=0.117N     |
|POLY 3             |     P=0.225      (e)          (e)          P=0.485     |P=0.165N     P=0.307N     P=0.120N     P=0.123N     |
|POLY 1.5           |     P=0.228      (e)          (e)          P=0.491     |P=0.165N     P=0.308N     P=0.121N     P=0.123N     |
|POLY 6             |     P=0.221      (e)          (e)          P=0.478     |P=0.165N     P=0.307N     P=0.120N     P=0.122N     |
|LOGISTIC REGRESSION|     P=0.231      (e)          (e)          P=0.496     |P=0.165N     P=0.307N     P=0.121N     P=0.123N     |
|COCH-ARM / FISHERS |     P=0.233      (e)          (e)          P=0.500     |P=0.165N     P=0.311N     P=0.123N     P=0.123N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Fibroma, Fibrosarcoma, Sarcoma, Myxoma, Myxosarcoma,                                                                        |
|     or Fibrous Histiocytoma                                                                                                     |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)  |4/100 (4%)   5/100 (5%)   2/100 (2%)   3/100 (3%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |4.4%         5.4%         2.2%         3.3%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    2/74 (3%)    1/79 (1%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |625          461          513          684          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.398N     P=0.509      P=0.325N     P=0.502N     |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.404N     P=0.506      P=0.336N     P=0.504N     |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.403N     P=0.504      P=0.339N     P=0.505N     |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.402N     P=0.508      P=0.337N     P=0.502N     |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.379N     P=0.515      P=0.328N     P=0.496N     |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.397N     P=0.500      P=0.341N     P=0.500N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 16
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Fibrosarcoma, Sarcoma, Myxosarcoma, or Fibrous Histiocytoma                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)  |4/100 (4%)   5/100 (5%)   2/100 (2%)   3/100 (3%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |4.4%         5.4%         2.2%         3.3%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    2/74 (3%)    1/79 (1%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |625          461          513          684          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.398N     P=0.509      P=0.325N     P=0.502N     |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.404N     P=0.506      P=0.336N     P=0.504N     |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.403N     P=0.504      P=0.339N     P=0.505N     |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.402N     P=0.508      P=0.337N     P=0.502N     |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.379N     P=0.515      P=0.328N     P=0.496N     |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.397N     P=0.500      P=0.341N     P=0.500N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Neurofibrosarcoma, Neurofibroma, or Schwannoma (benign,                                                                     |
|     malignant or NOS)                                                                                                           |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   1/100 (1%)   1/100 (1%)   1/100 (1%)  |2/100 (2%)   1/100 (1%)   4/100 (4%)   1/100 (1%)   |
|POLY-3 ADJUSTED (b)|     0.0%         1.1%         1.1%         1.2%        |2.2%         1.1%         4.3%         1.1%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    0/74 (0%)    2/79 (3%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          542          449          604         |608          672          578          576          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.542      P=0.498      P=0.500      P=0.482     |P=0.431N     P=0.495N     P=0.374      P=0.497N     |
|POLY 3             |     P=0.534      P=0.493      P=0.503      P=0.486     |P=0.433N     P=0.501N     P=0.346      P=0.502N     |
|POLY 1.5           |     P=0.542      P=0.496      P=0.502      P=0.491     |P=0.434N     P=0.501N     P=0.342      P=0.503N     |
|POLY 6             |     P=0.524      P=0.490      P=0.505      P=0.480     |P=0.430N     P=0.501N     P=0.348      P=0.500N     |
|LOGISTIC REGRESSION|     P=0.694N     P=0.556      P=0.442      P=0.575     |P=0.416N     P=0.495N     P=0.351      P=0.476N     |
|COCH-ARM / FISHERS |     P=0.556      P=0.500      P=0.500      P=0.500     |P=0.430N     P=0.500N     P=0.341      P=0.500N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 17
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Sarcoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   0/100 (0%)   0/100 (0%)  |4/100 (4%)   5/100 (5%)   2/100 (2%)   3/100 (3%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |4.4%         5.4%         2.2%         3.3%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    2/74 (3%)    1/79 (1%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |625          461          513          684          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.398N     P=0.509      P=0.325N     P=0.502N     |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.404N     P=0.506      P=0.336N     P=0.504N     |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.403N     P=0.504      P=0.339N     P=0.505N     |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.402N     P=0.508      P=0.337N     P=0.502N     |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.379N     P=0.515      P=0.328N     P=0.496N     |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.397N     P=0.500      P=0.341N     P=0.500N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Skin                                                                                                                             |
|     Schwannoma Malignant                                                                                                        |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   1/100 (1%)   1/100 (1%)  |2/100 (2%)   1/100 (1%)   4/100 (4%)   1/100 (1%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         1.1%         1.2%        |2.2%         1.1%         4.3%         1.1%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    0/84 (0%)    0/62 (0%)   |1/70 (1%)    0/74 (0%)    2/79 (3%)    0/74 (0%)    |
|FIRST INCIDENCE    |     ---          ---          449          604         |608          672          578          576          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.357      (e)          P=0.500      P=0.482     |P=0.431N     P=0.495N     P=0.374      P=0.497N     |
|POLY 3             |     P=0.351      (e)          P=0.503      P=0.486     |P=0.433N     P=0.501N     P=0.346      P=0.502N     |
|POLY 1.5           |     P=0.357      (e)          P=0.502      P=0.491     |P=0.434N     P=0.501N     P=0.342      P=0.503N     |
|POLY 6             |     P=0.344      (e)          P=0.505      P=0.480     |P=0.430N     P=0.501N     P=0.348      P=0.500N     |
|LOGISTIC REGRESSION|     P=0.512      (e)          P=0.442      P=0.575     |P=0.416N     P=0.495N     P=0.351      P=0.476N     |
|COCH-ARM / FISHERS |     P=0.366      (e)          P=0.500      P=0.500     |P=0.430N     P=0.500N     P=0.341      P=0.500N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 18
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Spleen                                                                                                                           |
|     Hemangiosarcoma                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     2/99 (2%)    5/98 (5%)    0/98 (0%)    3/93 (3%)   |0/91 (0%)    0/93 (0%)    0/95 (0%)    1/93 (1%)    |
|POLY-3 ADJUSTED (b)|     2.2%         5.6%         0.0%         3.7%        |0.0%         0.0%         0.0%         1.1%         |
|TERMINAL (d)       |     2/76 (3%)    3/72 (4%)    0/84 (0%)    2/62 (3%)   |0/70 (0%)    0/74 (0%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      400          ---          726         |---          ---          ---          715          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.543      P=0.207      P=0.217N     P=0.411     |P=0.236      (e)          (e)          P=0.505      |
|POLY 3             |     P=0.567      P=0.208      P=0.238N     P=0.445     |P=0.236      (e)          (e)          P=0.505      |
|POLY 1.5           |     P=0.577      P=0.212      P=0.239N     P=0.456     |P=0.235      (e)          (e)          P=0.504      |
|POLY 6             |     P=0.556      P=0.204      P=0.236N     P=0.434     |P=0.237      (e)          (e)          P=0.506      |
|LOGISTIC REGRESSION|     P=0.614N     P=0.263      (e)          P=0.419     |P=0.234      (e)          (e)          P=0.504      |
|COCH-ARM / FISHERS |     P=0.593      P=0.218      P=0.251N     P=0.470     |P=0.234      (e)          (e)          P=0.505      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Testes                                                                                                                           |
|     Adenoma                                                                                                                     |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/99 (1%)    1/98 (1%)    2/100 (2%)   1/96 (1%)   |                                                    |
|POLY-3 ADJUSTED (b)|     1.1%         1.1%         2.1%         1.2%        |                                                    |
|TERMINAL (d)       |     1/76 (1%)    1/72 (1%)    1/84 (1%)    1/62 (2%)   |                                                    |
|FIRST INCIDENCE    |     734 (T)      734 (T)      701          734 (T)     |                                                    |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.658      P=0.749      P=0.529      P=0.715     |                                                    |
|POLY 3             |     P=0.656N     P=0.749      P=0.505      P=0.739     |                                                    |
|POLY 1.5           |     P=0.649N     P=0.753      P=0.504      P=0.745     |                                                    |
|POLY 6             |     P=0.664N     P=0.745      P=0.507      P=0.732     |                                                    |
|LOGISTIC REGRESSION|     P=0.669N     P=0.749      P=0.505      P=0.715     |                                                    |
|COCH-ARM / FISHERS |     P=0.639N     P=0.749      P=0.504      P=0.744     |                                                    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 19
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|Thymus                                                                                                                           |
|     Thymoma: Benign, Malignant, NOS                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |                                                        |                                                    |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/69 (0%)    0/68 (0%)    0/63 (0%)    0/68 (0%)   |1/78 (1%)    2/92 (2%)    0/84 (0%)    0/75 (0%)    |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         0.0%         0.0%        |1.4%         2.4%         0.0%         0.0%         |
|TERMINAL (d)       |     0/54 (0%)    0/51 (0%)    0/58 (0%)    0/41 (0%)   |1/62 (2%)    1/69 (1%)    0/70 (0%)    0/60 (0%)    |
|FIRST INCIDENCE    |     ---          ---          ---          ---         |735 (T)      672          ---          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     (e)          (e)          (e)          (e)         |P=0.252N     P=0.525      P=0.476N     P=0.507N     |
|POLY 3             |     (e)          (e)          (e)          (e)         |P=0.266N     P=0.548      P=0.488N     P=0.512N     |
|POLY 1.5           |     (e)          (e)          (e)          (e)         |P=0.266N     P=0.551      P=0.487N     P=0.511N     |
|POLY 6             |     (e)          (e)          (e)          (e)         |P=0.267N     P=0.544      P=0.490N     P=0.513N     |
|LOGISTIC REGRESSION|     (e)          (e)          (e)          (e)         |P=0.265N     P=0.554      (e)          (e)          |
|COCH-ARM / FISHERS |     (e)          (e)          (e)          (e)         |P=0.264N     P=0.562      P=0.481N     P=0.510N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Hemangioma                                                                                                                  |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     0/100 (0%)   0/100 (0%)   1/100 (1%)   0/100 (0%)  |0/100 (0%)   2/100 (2%)   1/100 (1%)   2/100 (2%)   |
|POLY-3 ADJUSTED (b)|     0.0%         0.0%         1.1%         0.0%        |0.0%         2.2%         1.1%         2.2%         |
|TERMINAL (d)       |     0/76 (0%)    0/72 (0%)    1/84 (1%)    0/62 (0%)   |0/70 (0%)    1/74 (1%)    1/79 (1%)    2/74 (3%)    |
|FIRST INCIDENCE    |     ---          ---          734 (T)      ---         |---          559          735 (T)      735 (T)      |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.804N     (e)          P=0.520      (e)         |P=0.375      P=0.245      P=0.524      P=0.251      |
|POLY 3             |     P=0.775N     (e)          P=0.501      (e)         |P=0.368      P=0.240      P=0.501      P=0.237      |
|POLY 1.5           |     P=0.772N     (e)          P=0.501      (e)         |P=0.368      P=0.239      P=0.500      P=0.237      |
|POLY 6             |     P=0.779N     (e)          P=0.503      (e)         |P=0.370      P=0.240      P=0.502      P=0.238      |
|LOGISTIC REGRESSION|     (e)          (e)          P=0.520      (e)         |P=0.371      P=0.245      P=0.524      P=0.251      |
|COCH-ARM / FISHERS |     P=0.767N     (e)          P=0.500      (e)         |P=0.371      P=0.249      P=0.500      P=0.249      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 20
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Hemangiosarcoma                                                                                                             |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     6/100 (6%)   10/100 (10%) 6/100 (6%)   8/100 (8%)  |2/100 (2%)   3/100 (3%)   1/100 (1%)   5/100 (5%)   |
|POLY-3 ADJUSTED (b)|     6.4%         11.0%        6.4%         9.2%        |2.2%         3.3%         1.1%         5.5%         |
|TERMINAL (d)       |     3/76 (4%)    6/72 (8%)    3/84 (4%)    5/62 (8%)   |0/70 (0%)    3/74 (4%)    1/79 (1%)    2/74 (3%)    |
|FIRST INCIDENCE    |     582          400          585          518         |707          735 (T)      735 (T)      699          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.398      P=0.193      P=0.574N     P=0.275     |P=0.139      P=0.516      P=0.483N     P=0.237      |
|POLY 3             |     P=0.473      P=0.199      P=0.611N     P=0.335     |P=0.131      P=0.499      P=0.498N     P=0.219      |
|POLY 1.5           |     P=0.497      P=0.207      P=0.614N     P=0.357     |P=0.130      P=0.499      P=0.500N     P=0.217      |
|POLY 6             |     P=0.445      P=0.189      P=0.605N     P=0.311     |P=0.132      P=0.498      P=0.498N     P=0.221      |
|LOGISTIC REGRESSION|     P=0.541N     P=0.264      P=0.615      P=0.403     |P=0.131      P=0.500      P=0.498N     P=0.218      |
|COCH-ARM / FISHERS |     P=0.536      P=0.218      P=0.616N     P=0.391     |P=0.133      P=0.500      P=0.500N     P=0.222      |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Hemangiosarcoma or Hemangioma                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     6/100 (6%)   10/100 (10%) 7/100 (7%)   8/100 (8%)  |2/100 (2%)   5/100 (5%)   2/100 (2%)   7/100 (7%)   |
|POLY-3 ADJUSTED (b)|     6.4%         11.0%        7.4%         9.2%        |2.2%         5.5%         2.2%         7.8%         |
|TERMINAL (d)       |     3/76 (4%)    6/72 (8%)    4/84 (5%)    5/62 (8%)   |0/70 (0%)    4/74 (5%)    2/79 (3%)    4/74 (5%)    |
|FIRST INCIDENCE    |     582          400          585          518         |707          559          735 (T)      699          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.412      P=0.193      P=0.546      P=0.275     |P=0.092      P=0.236      P=0.668N     P=0.099      |
|POLY 3             |     P=0.488      P=0.199      P=0.506      P=0.335     |P=0.084      P=0.222      P=0.691N     P=0.084      |
|POLY 1.5           |     P=0.514      P=0.207      P=0.503      P=0.357     |P=0.084      P=0.221      P=0.692N     P=0.083      |
|POLY 6             |     P=0.460      P=0.189      P=0.513      P=0.311     |P=0.085      P=0.223      P=0.691N     P=0.085      |
|LOGISTIC REGRESSION|     P=0.526N     P=0.264      P=0.497      P=0.403     |P=0.084      P=0.221      P=0.691N     P=0.085      |
|COCH-ARM / FISHERS |     P=0.553      P=0.218      P=0.500      P=0.391     |P=0.086      P=0.222      P=0.689N     P=0.085      |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 21
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Histiocytic Sarcoma                                                                                                         |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     1/100 (1%)   1/100 (1%)   3/100 (3%)   1/100 (1%)  |2/100 (2%)   2/100 (2%)   2/100 (2%)   0/100 (0%)   |
|POLY-3 ADJUSTED (b)|     1.1%         1.1%         3.2%         1.2%        |2.2%         2.2%         2.2%         0.0%         |
|TERMINAL (d)       |     1/76 (1%)    0/72 (0%)    2/84 (2%)    0/62 (0%)   |2/70 (3%)    1/74 (1%)    0/79 (0%)    0/74 (0%)    |
|FIRST INCIDENCE    |     734 (T)      703          717          466         |735 (T)      721          655          ---          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.639N     P=0.747      P=0.342      P=0.736     |P=0.159N     P=0.675N     P=0.674N     P=0.227N     |
|POLY 3             |     P=0.602N     P=0.751      P=0.310      P=0.745     |P=0.162N     P=0.693      P=0.688N     P=0.240N     |
|POLY 1.5           |     P=0.592N     P=0.755      P=0.308      P=0.751     |P=0.162N     P=0.692      P=0.691N     P=0.240N     |
|POLY 6             |     P=0.612N     P=0.748      P=0.313      P=0.738     |P=0.161N     P=0.692N     P=0.686N     P=0.239N     |
|LOGISTIC REGRESSION|     P=0.548N     P=0.753      P=0.315      P=0.680N    |P=0.160N     P=0.691N     P=0.693      (e)          |
|COCH-ARM / FISHERS |     P=0.579N     P=0.751N     P=0.311      P=0.751N    |P=0.159N     P=0.689N     P=0.689N     P=0.249N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Malignant Lymphoma: Histiocytic, Lymphocytic, Mixed,                                                                        |
|     NOS, or Undifferentiated Cell Type                                                                                          |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     8/100 (8%)   7/100 (7%)   4/100 (4%)   7/100 (7%)  |32/100 (32%) 31/100 (31%) 22/100 (22%) 26/100 (26%) |
|POLY-3 ADJUSTED (b)|     8.6%         7.8%         4.3%         8.0%        |34.7%        33.5%        24.0%        28.3%        |
|TERMINAL (d)       |     7/76 (9%)    4/72 (6%)    3/84 (4%)    3/62 (5%)   |23/70 (33%)  23/74 (31%)  20/79 (25%)  20/74 (27%)  |
|FIRST INCIDENCE    |     691          562          701          510         |461          461          581          467          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.444      P=0.543N     P=0.147N     P=0.575     |P=0.238N     P=0.421N     P=0.034N*    P=0.172N     |
|POLY 3             |     P=0.536      P=0.522N     P=0.182N     P=0.550N    |P=0.253N     P=0.494N     P=0.074N     P=0.219N     |
|POLY 1.5           |     P=0.552      P=0.514N     P=0.184N     P=0.531N    |P=0.257N     P=0.499N     P=0.076N     P=0.225N     |
|POLY 6             |     P=0.518      P=0.531N     P=0.178N     P=0.571N    |P=0.247N     P=0.488N     P=0.074N     P=0.213N     |
|LOGISTIC REGRESSION|     P=0.565N     P=0.497N     P=0.177N     P=0.510N    |P=0.259N     P=0.502N     P=0.071N     P=0.226N     |
|COCH-ARM / FISHERS |     P=0.578      P=0.500N     P=0.186N     P=0.500N    |P=0.250N     P=0.500N     P=0.076N     P=0.218N     |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 22
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Benign Tumors                                                                                                               |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     54/100 (54%) 50/100 (50%) 54/100 (54%) 47/100 (47%)|52/100 (52%) 49/100 (49%) 54/100 (54%) 49/100 (49%) |
|POLY-3 ADJUSTED (b)|     57.7%        54.8%        56.5%        51.3%       |56.2%        52.2%        58.6%        54.1%        |
|TERMINAL (d)       |     47/76 (62%)  42/72 (58%)  46/84 (55%)  30/62 (48%) |44/70 (63%)  38/74 (51%)  49/79 (62%)  46/74 (62%)  |
|FIRST INCIDENCE    |     646          542          562          483         |542          64           578          566          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.331      P=0.492N     P=0.300N     P=0.438     |P=0.364N     P=0.278N     P=0.350N     P=0.249N     |
|POLY 3             |     P=0.234N     P=0.402N     P=0.490N     P=0.230N    |P=0.496N     P=0.339N     P=0.431      P=0.442N     |
|POLY 1.5           |     P=0.227N     P=0.373N     P=0.520N     P=0.219N    |P=0.477N     P=0.351N     P=0.427      P=0.432N     |
|POLY 6             |     P=0.236N     P=0.436N     P=0.443N     P=0.238N    |P=0.516N     P=0.326N     P=0.421      P=0.452N     |
|LOGISTIC REGRESSION|     P=0.355N     P=0.501N     P=0.540N     P=0.329N    |P=0.425N     P=0.391N     P=0.465      P=0.395N     |
|COCH-ARM / FISHERS |     P=0.211N     P=0.336N     P=0.556N     P=0.198N    |P=0.404N     P=0.389N     P=0.444      P=0.389N     |
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Malignant Tumors                                                                                                            |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     40/100 (40%) 49/100 (49%) 45/100 (45%) 49/100 (49%)|55/100 (55%) 58/100 (58%) 39/100 (39%) 40/100 (40%) |
|POLY-3 ADJUSTED (b)|     41.3%        50.3%        46.1%        51.4%       |57.6%        59.6%        41.1%        42.5%        |
|TERMINAL (d)       |     25/76 (33%)  27/72 (38%)  35/84 (42%)  23/62 (37%) |34/70 (49%)  37/74 (50%)  29/79 (37%)  26/74 (35%)  |
|FIRST INCIDENCE    |     520          400          430          448         |397          461          513          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.062      P=0.108      P=0.460      P=0.037 *   |P=0.023N*    P=0.503      P=0.010N*    P=0.030N*    |
|POLY 3             |     P=0.205      P=0.134      P=0.302      P=0.103     |P=0.014N*    P=0.448      P=0.015N*    P=0.024N*    |
|POLY 1.5           |     P=0.222      P=0.132      P=0.296      P=0.111     |P=0.012N*    P=0.419      P=0.016N*    P=0.024N*    |
|POLY 6             |     P=0.188      P=0.136      P=0.307      P=0.095     |P=0.015N*    P=0.477      P=0.015N*    P=0.025N*    |
|LOGISTIC REGRESSION|     P=0.408      P=0.192      P=0.274      P=0.219     |P=0.012N*    P=0.387      P=0.017N*    P=0.024N*    |
|COCH-ARM / FISHERS |     P=0.255      P=0.127      P=0.284      P=0.127     |P=0.011N*    P=0.388      P=0.017N*    P=0.024N*    |
|=================================================================================================================================|
       Date:  01/06/98                           EXPERIMENT: 89029 TEST: 06                                            Page 23
                     Statistical Analysis of Primary Tumors in Mice(B6C3F1)       -                MAGNETIC FIELDS (EMF)
                                         Terminal Sacrifice at 104 weeks 
|=================================================================================================================================|
|                   |                                                        |                                                    |
|                   |                              Males                     |                       Females                      |
|Dose               |     SHAM         0.02         2 GAUSS      10 GAUSS    |SHAM         0.02         2 GAUSS      10 GAUSS     |
|                   |     CONTROL      GAUSS                                 |CONTROL      GAUSS                                  |
|=================================================================================================================================|
|                                                                                                                                 |
|All Organs                                                                                                                       |
|     Malignant and Benign Tumors                                                                                                 |
|                                                                                                                                 |
|                                                                                                                                 |
|---------------------------------------------------------------------------------------------------------------------------------|
|TUMOR RATES        |     #            #            #            #           |#            #            #            #            |
|-----------        |                                                        |                                                    |
|OVERALL (a)        |     71/100 (71%) 81/100 (81%) 72/100 (72%) 74/100 (74%)|78/100 (78%) 80/100 (80%) 72/100 (72%) 71/100 (71%) |
|POLY-3 ADJUSTED (b)|     73.0%        82.2%        73.3%        76.5%       |81.0%        81.2%        75.8%        74.9%        |
|TERMINAL (d)       |     53/76 (70%)  56/72 (78%)  60/84 (71%)  43/62 (69%) |54/70 (77%)  56/74 (76%)  60/79 (76%)  55/74 (74%)  |
|FIRST INCIDENCE    |     520          400          430          448         |397          64           513          183          |
|-------------------|                                                        |                                                    |
|STATISTICAL TESTS  |                                                        |                                                    |
|-------------------|                                                        |                                                    |
|LIFE TABLE         |     P=0.081      P=0.060      P=0.310N     P=0.050     |P=0.143N     P=0.492N     P=0.064N     P=0.131N     |
|POLY 3             |     P=0.506N     P=0.081      P=0.547      P=0.343     |P=0.158N     P=0.561      P=0.237N     P=0.193N     |
|POLY 1.5           |     P=0.483N     P=0.075      P=0.533      P=0.353     |P=0.139N     P=0.522      P=0.236N     P=0.185N     |
|POLY 6             |     P=0.523N     P=0.087      P=0.556      P=0.338     |P=0.181N     P=0.552N     P=0.259N     P=0.208N     |
|LOGISTIC REGRESSION|     P=0.425N     P=0.067      P=0.502      P=0.352     |P=0.116N     P=0.426      P=0.196N     P=0.184N     |
|COCH-ARM / FISHERS |     P=0.435N     P=0.068      P=0.500      P=0.376     |P=0.103N     P=0.431      P=0.207N     P=0.165N     |
|=================================================================================================================================|

(a)  Number of tumor-bearing animals /  number of animals examined at site.
(b)  Poly-3 adjusted lifetime tumor incidence.
(d)  Observed incidence at terminal kill.
(f)  Beneath the control incidence are the P-values associated with the trend 
test.  Beneath the dosed group incidence are the P-values corresponding to 
pairwise comparisons between the controls and that dosed group.  The life
table analysis regards tumors in animals dying prior to  terminal kill as
 being (directly or indirectly) the cause of death.
Logistic regression is an alternative
 method for analyzing the incidence of non-fatal tumors. The Cochran-Armitage
and Fishers exact tests compare directly the overall incidence rates
For all tests a negative trend is indicated by N
(e)  Value of Statistic cannot be computed.
(I)  Interim sacrifice
(T)  Terminal sacrifice
#   Tumor rates based on number of animals necropsied.
*   To the right of any statistical result, indicates significance at (P<=0.05).
**  To the right of any statistical result, indicates significance at (P<=0.01).
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.