TDMS Study 93023-07 Pathology Tables
NTP STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS REPORT: PEIRPT10
LAB: Southern Research Inst 2,4-HEXADIENAL DATE: 02/15/01
EXPERIMENT: 93023 TEST: 07 TIME: 11:21:33
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE PAGE: 1
CONT: N01-ES-55393 ROUTE: GAVAGE NTP C#: 93023B
PATHOLOGIST: FARNELL, DANIEL R. CAS: 142-83-6
------------------------------------------------------------------------------------------------------------------------------------
FINAL #1/MICE
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS REPORT: PEIRPT10
LAB: Southern Research Inst 2,4-HEXADIENAL DATE: 02/15/01
EXPERIMENT: 93023 TEST: 07 TIME: 11:21:33
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE
CONT: N01-ES-55393 ROUTE: GAVAGE NTP C#: 93023B
PATHOLOGIST: FARNELL, DANIEL R. CAS: 142-83-6
SUMMARY OF STATISTICALLY SIGNIFICANT (P<=.05) RESULTS
IN THE ANALYSIS OF 2,4-HEXADIENAL
===============================================================
Male Mice
------------
Organ Morphology
----- ----------
Adrenal Cortex Accessory Adrenal Cortical Nodule
Heart Infiltration Cellular Mixed Cell
Liver: Hepatocyte Mixed Cell Focus
Lung: Alveolar Epithelium Hyperplasia
Lymph Node, Mediastinal Hyperplasia
Spleen Hematopoietic Cell Proliferation
Stomach, Forestomach Ulcer
Stomach, Forestomach: Epithelium Hyperplasia
Stomach, Glandular: Glands Degeneration Cystic Focal
===============================================================
Female Mice
------------
Organ Morphology
----- ----------
Liver Infiltration Cellular Mixed Cell
Liver: Hepatocyte, Midzonal Vacuolization Cytoplasmic
Nose: Mucosa, Glands Dilatation Focal
Nose: Olfactory Epithelium Cytoplasmic Alteration
Spleen Hematopoietic Cell Proliferation
Stomach, Forestomach: Epithelium Hyperplasia
Thymus Cyst
Thyroid Gland Degeneration Cystic Focal
Uterus Hydrometra
Uterus: Endometrium Hyperplasia Cystic
===============================================================
Date: 02/15/01 EXPERIMENT: 93023 TEST: 07 Page 1
Statistical Analysis of Non-neoplastic Lesions in Mice(B6C3F1) - 2,4-HEXADIENAL
Terminal Sacrifice at 105 weeks
|=================================================================================================================================|
| | | |
| | Males | Females |
|Dose | 0 30 60 120 |0 30 60 120 |
| | MG/KG/DY MG/KG/DY MG/KG/DY MG/KG/DY |MG/KG/DY MG/KG/DY MG/KG/DY MG/KG/DY |
|=================================================================================================================================|
| |
|Adrenal Cortex |
| Accessor