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TDMS Study 96010-04 Pathology Tables

NTP  EXP/TEST: 96010-04                 WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)                           PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 03/26/03
ROUTE: DOSED WATER                                                                                                TIME: 10:31:41

                                                         EIS REPORT 03
                                                         FINAL #1/MICE


       FACILITY:  Southern Research Institute

       NTP C#:  96010A

       CONTRACT NUMBER:  N01-ES-85420

       CAS NUMBER:  7775-09-9

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96010-04                 WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)                           PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 03/26/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 10:31:41
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 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 106    FIRST DOSE: 09/30/98
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             50     18.4    0.9        36     61.0    9.5                     36     42.5    9.6

 500 MG/L           50     18.2    0.9        34     54.3    9.0        89.0         34     36.1    8.8

 1000MG/L           50     18.4    1.0        31     55.0    9.9        90.1         31     36.7   10.0

 2000MG/L           50     18.3    1.0        35     54.6   10.6        89.5         35     36.3   10.6




----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: MALE        WEEK ON DOSE: 106    FIRST DOSE: 09/30/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             50     22.2    1.2        38     46.6    7.7                     38     24.4    7.5

 500 MG/L           50     22.4    1.4        41     45.1    9.8        96.7         41     22.6    9.7

 1000MG/L           50     22.2    1.3        41     46.5    8.8        99.7         41     24.2    9.0

 2000MG/L           50     22.3    1.1        33     48.5   10.5       104.0         33     26.2   10.6

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