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NCTR Study 211601 Pathology Tables

NCTR EXP/TEST:   211601                                                                                      PAGE:    1
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:02.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9|   U      O|
CONTRL F2YR   01     1                      | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +  A  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  A  M  +  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
INTESTINE LARGE,COLON                       | +  +  +  +  +  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X     X                                              |          |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  A  A  +  A  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  A  +  A  A  A  A  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
INTESTINE SMALL,ILEUM                       | +  +  A  A  +  A  A  A  A  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  A  +  A  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X                                                    |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                          X                |          |
  HEPATOCELLULAR CARCINOMA                  |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |       X              X     X     X                             X          |          |
MESENTERY                                   |                            +                                              |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                                  X                                        |          |
  LYMPHOMA MALIGNANT                        |                            X                                   X          |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X     X                             X          |          |
STOMACH                                     | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  PAPILLOMA SQUAMOUS                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +  M  +  +  M  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  M  +  M  +  +  M  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    2
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:02.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9|   U      O|
CONTRL F2YR   01     1                      | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                X          |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                X          |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                X          |          |
  PHEOCHROMOCYTOMA MALIGNANT                |                                                                           |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  M  +  M  +  +  +  M  M  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
PITUITARY GLAND                             | +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,PARS INTERMEDIA                   |             X                                                             |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                +          |          |
  LYMPHOMA MALIGNANT,FAT                    |                                                                X          |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | M  +  +  M  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CYSTADENOMA                               |                                                                   X       |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  LUTEOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                                X          |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                   X                                                       |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  POLYP                                     |                                                                           |          |
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                         X                                               X |          |
  LYMPHOMA MALIGNANT                        |                            X                                   X          |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    3
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:02.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9|   U      O|
CONTRL F2YR   01     1                      | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        |       X                    X     X                                        |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA,LUMBAR                |                         X                                                 |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                  X                                        |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                            X                                              |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                    X                                   X          |          |
LYMPH NODE,MESENTERIC                       | +  +  +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |       X        X     X     X                                   X          |          |
SPLEEN                                      | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        |       X        X     X     X     X                             X          |          |
THYMUS                                      | M  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X     X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  + |          |
  FIBROSARCOMA                              |                                  X                                        |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
SKIN                                        | +  +  +  +  M  M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    4
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:02.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 3| 6| 0| 5| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 0| 6| 7| 5| 0| 5| 7| 8| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 3| 2| 2| 0| 4| 2| 4| 0| 4| 5| 5| 5| 5| 6| 6| 5| 5| 5| 6| 6| 6| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 3| 8| 6| 7| 8| 0| 1| 1| 8| 9| 9| 9| 9| 2| 3| 2| 3| 3| 6| 6| 5| 9| 9| 9|   U      O|
CONTRL F2YR   01     1                      | 1| 8| 8| 3| 9| 2| 4| 0| 2| 9| 1| 2| 3| 4| 9| 0| 9| 0| 1| 6| 7| 3| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  M  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                  X                                        |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |       X                    X                                   X          |          |
NOSE                                        | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  A  +  A  A  A  A  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
  CARCINOMA                                 |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                   X          |          |
LACRIMAL GLAND                              | +  +  +  M  +  +  M  M  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                X          |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |       X        X           X                                   X          |          |
URINARY BLADDER                             | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X                                   X          |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    5
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:09.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8|         U      O|
CONTRL F2YR   01     1                      | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 44       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 40       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 40       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                           X                               |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA                  |                                                             X             |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                   X       |         6|
MESENTERY                                   |                                                                           |  1       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROSARCOMA                              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  PAPILLOMA SQUAMOUS                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    6
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:10.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8|         U      O|
CONTRL F2YR   01     1                      | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  PHEOCHROMOCYTOMA MALIGNANT                |                            X                                              |         1|
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PARATHYROID GLAND                           | +  M  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  M  +  +       | 38       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 45       |
  ADENOMA,PARS INTERMEDIA                   |                                           X                               |         2|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                           |  1       |
  LYMPHOMA MALIGNANT,FAT                    |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CYSTADENOMA                               |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LUTEOMA                                   |       X                                                                   |         1|
  LYMPHOMA MALIGNANT                        |                               X                                           |         2|
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                                           |         1|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                             X             |         2|
  POLYP                                     |       X                                                                   |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    7
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:10.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8|         U      O|
CONTRL F2YR   01     1                      | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA,LUMBAR                |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                   X       |         2|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                   X       |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                   X       |         4|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                   X       |         6|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                           X                       X       |         8|
THYMUS                                      | +  +  +  +  +  +  +  M  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                   X       |         3|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  FIBROSARCOMA                              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  HEMANGIOSARCOMA                           |    X                                                                      |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    8
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:10.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 9| 9| 3| 3| 3| 3| 3| 3| 1| 1| 1| 1| 2| 2| 2| 2| 8| 8| 8| 8| 8| 8| 8|         U      O|
CONTRL F2YR   01     1                      | 3| 4| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 0| 1| 2| 3| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                   X       |         4|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 41       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |             X                             X                               |         2|
  CARCINOMA                                 |                                     X                                     |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  +       | 43       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                               X                                   X       |         6|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                   X       |         3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:    9
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:13.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8|   U      O|
25MG   F2YR   02     2                      | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  M                    +  +                               |          |
GALLBLADDER                                 | +  +  +  +  +  +  M                    +  +                               |          |
INTESTINE LARGE                             | +  A  +  +  +  +  +                    +  +                               |          |
INTESTINE LARGE,CECUM                       | +  A  +  A  +  +  A                    +  +                               |          |
INTESTINE LARGE,COLON                       | +  A  +  +  +  +  +                    +  +                               |          |
INTESTINE LARGE,RECTUM                      | +  A  +  M  +  +  +                    +  +                               |          |
INTESTINE SMALL                             | +  A  +  A  +  +  A                    +  +                               |          |
INTESTINE SMALL,DUODENUM                    | +  A  +  A  +  +  A                    +  +                               |          |
INTESTINE SMALL,ILEUM                       | +  A  +  A  +  +  A                    +  +                               |          |
INTESTINE SMALL,JEJUNUM                     | +  A  +  A  +  +  A                    +  +                               |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                           X                               |          |
  HISTIOCYTIC SARCOMA                       |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X     X                                                                |          |
MESENTERY                                   |                                                                           |          |
PANCREAS                                    | M  +  +  A  +  +  +                    +  +                               |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +                    +  +                               |          |
STOMACH                                     | +  +  +  +  +  +  +                    +  +                               |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +                    +  +                               |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +                    +  +                               |          |
TONGUE                                      | +  +  +  +  +  +  +                    A  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  M  +  +  +                    +  +                               |          |
BLOOD VESSEL,AORTA                          | +  +  +  M  +  +  +                    +  +                               |          |
HEART                                       | +  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  M  +  +  +  +  +                    +  +                               |          |
ADRENAL GLAND,CORTEX                        | +  M  +  +  +  +  +                    +  +                               |          |
  HISTIOCYTIC SARCOMA                       |                X                                                          |          |
ADRENAL GLAND,MEDULLA                       | +  M  +  +  +  +  +                    +  +                               |          |
ISLETS, PANCREATIC                          | M  +  +  A  +  +  +                    +  +                               |          |
PARATHYROID GLAND                           | M  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   10
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:14.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8|   U      O|
25MG   F2YR   02     2                      | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PITUITARY GLAND                             | M  M  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |                   X                                                       |          |
THYROID GLAND                               | M  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | M  M  +  +  +  +  +                    +  +                               |          |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +  +  +                |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
UTERUS                                      | +  +  +  +  +  +  +              +     +  +        +  +     +     +       |          |
  HISTIOCYTIC SARCOMA                       |                X                                                          |          |
VAGINA                                      | +  +  +  +  +  M  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +                    +  +                               |          |
LYMPH NODE                                  | +  +  +  +  +  +  +                    +  +                               |          |
  FIBROSARCOMA,INGUINAL                     |                                                                           |          |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |       X                                                                   |          |
  LYMPHOMA MALIGNANT,RENAL                  |          X                                                                |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +                    +  +                               |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  M  +  A                    +  +                               |          |
  HISTIOCYTIC SARCOMA                       |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |    X  X  X                                                                |          |
SPLEEN                                      | +  +  +  +  +  +  +        +           +  +  +                            |          |
  LYMPHOMA MALIGNANT                        |    X  X  X                                                                |          |
THYMUS                                      | +  M  M  +  +  +  M                    M  +                               |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  +  M  +  +  +                    +  +                               |          |
  ADENOMA                                   |                                           X                               |          |
SKIN                                        | +  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   11
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:14.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8|   U      O|
25MG   F2YR   02     2                      | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

  HISTIOCYTIC SARCOMA                       |                                        X                                  |          |
  OSTEOSARCOMA,METASTATIC,BONE              |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +                    +  +                               |          |
  OSTEOSARCOMA,LUMBAR,VERTEBRA              |             X                                                             |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +                    +  +                               |          |
BONE,STERNUM                                | +  +  +  +  +  +  +                    +  +                               |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +                    A  +                    +          |          |
  FIBROSARCOMA                              |                                                                X          |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +                    +  +                               |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +                    +  +                               |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +                    +  +                               |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +                    A  +                               |          |
SPINAL CORD                                 | +  +  +  +  +  +  +                    +  +                               |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  M  M  +  +  M  M                    +  +                               |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                            X                                              |          |
  HISTIOCYTIC SARCOMA                       |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
  OSTEOSARCOMA,METASTATIC,BONE              |             X                                                             |          |
NOSE                                        | +  +  +  +  +  +  +                    +  +                               |          |
TRACHEA                                     | +  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  A  +  A  +  +  A                    A  +                               |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +                    A  +                               |          |
  ADENOMA                                   |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   12
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:14.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 6| 6| 6| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 2| 2| 9| 6| 3| 9| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 1| 8| 8| 3| 7| 9| 6| 6| 6| 6| 6| 6| 6| 1| 5| 5| 5| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 7| 7| 9| 7| 9| 1| 5| 5| 5| 6| 6| 6| 2| 2| 2| 2| 2| 6| 6| 6| 8| 8| 8| 8|   U      O|
25MG   F2YR   02     2                      | 2| 4| 6| 7| 8| 0| 7| 7| 8| 9| 0| 1| 2| 4| 5| 6| 7| 8| 3| 4| 5| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              | +  +  +  +  +  M  M                    M  +                               |          |
ZYMBAL'S GLAND                              | +  M  +  M  +  M  M                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  A                    +  +                               |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
URINARY BLADDER                             | +  +  +  +  +  +  +                    +  +                               |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   13
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:15.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0|         U      O|
25MG   F2YR   02     2                      | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                           +                               |  9       |
GALLBLADDER                                 |                                           M                               |  8       |
INTESTINE LARGE                             |                                           +                               |  9       |
INTESTINE LARGE,CECUM                       |                                           A                               |  6       |
INTESTINE LARGE,COLON                       |                                           +                               |  9       |
INTESTINE LARGE,RECTUM                      |                                           +                               |  8       |
INTESTINE SMALL                             |                                           +                               |  7       |
INTESTINE SMALL,DUODENUM                    |                                           +                               |  7       |
INTESTINE SMALL,ILEUM                       |                                           A                               |  6       |
INTESTINE SMALL,JEJUNUM                     |                                           A                               |  6       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |    X                                                                      |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X                             X  X                            |         5|
MESENTERY                                   |                            +                                              |  1       |
PANCREAS                                    |                                           +                               |  8       |
  LYMPHOMA MALIGNANT                        |                                           X                               |         1|
SALIVARY GLANDS                             |                                  +        M                               | 10       |
STOMACH                                     |                                           +                               | 10       |
STOMACH,FORESTOMACH                         |                                           +                               | 10       |
STOMACH,GLANDULAR                           |                                           +                               | 10       |
TONGUE                                      |                                           +                               |  9       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                           M                               |  8       |
BLOOD VESSEL,AORTA                          |                                           M                               |  8       |
HEART                                       |                                           +                               | 10       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                           +                               |  9       |
ADRENAL GLAND,CORTEX                        |                                           +                               |  9       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       |                                           +                               |  9       |
ISLETS, PANCREATIC                          |                                           +                               |  8       |
PARATHYROID GLAND                           |                                           +                               |  9       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   14
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:15.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0|         U      O|
25MG   F2YR   02     2                      | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  ADENOMA,PARS DISTALIS                     |                   X                                                       |         2|
THYROID GLAND                               |                                           +                               |  9       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              |                                           +                               |  8       |
OVARY                                       | +                 +  +  +  +        +  +  +              +  +  +          | 29       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
UTERUS                                      | +        +        +  +  +     +  +     +  A     +  +     +     +          | 26       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
VAGINA                                      |                                           +                               |  9       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                           +                               | 10       |
LYMPH NODE                                  |       +     +                    +        +                               | 13       |
  FIBROSARCOMA,INGUINAL                     |       X                                                                   |         1|
  LYMPHOMA MALIGNANT,AXILLARY               |             X                                                             |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |             X                                                             |         1|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                           X                               |         2|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       |                                  +        +                               | 11       |
  LYMPHOMA MALIGNANT                        |                                  X        X                               |         3|
LYMPH NODE,MESENTERIC                       |             +                             +                               |  9       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X                                                             |         4|
SPLEEN                                      |             +                             +  +                            | 14       |
  LYMPHOMA MALIGNANT                        |             X                             X  X                            |         6|
THYMUS                                      |                                           M                               |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                           M                               |  6       |
  ADENOMA                                   |                                                                           |         1|
SKIN                                        |                                           +                               | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   15
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:15.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0|         U      O|
25MG   F2YR   02     2                      | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  OSTEOSARCOMA,METASTATIC,BONE              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                           +                               | 10       |
  OSTEOSARCOMA,LUMBAR,VERTEBRA              |                                                                           |         1|
BONE,FEMUR                                  |                                           +                               | 10       |
BONE,STERNUM                                |                                           +                               | 10       |
SKELETAL MUSCLE                             |       +                                   +                               | 11       |
  FIBROSARCOMA                              |       X                                                                   |         2|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                                           +                               | 10       |
BRAIN,CEREBELLUM                            |                                           +                               | 10       |
BRAIN,CEREBRUM                              |                                           +                               | 10       |
PERIPHERAL NERVE                            |                                           +                               |  9       |
SPINAL CORD                                 |                                           +                               | 10       |
SPINAL CORD,THORACIC                        |                                           +                               | 10       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                           M                               |  5       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X                             X  X                            |         4|
  OSTEOSARCOMA,METASTATIC,BONE              |                                                                           |         1|
NOSE                                        |                                           +                               | 10       |
TRACHEA                                     |                                           M                               |  9       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                                           A                               |  4       |
HARDERIAN GLAND                             |                                        +  +                               | 10       |
  ADENOMA                                   |                                        X                                  |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   16
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:15.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 8| 8| 8| 7| 7| 7| 7| 7| 7| 2| 2| 3| 3| 3| 3| 3| 0| 0| 0| 0| 0| 0| 0|         U      O|
25MG   F2YR   02     2                      | 7| 8| 9| 1| 2| 3| 4| 5| 6| 8| 9| 0| 1| 2| 3| 4| 2| 3| 4| 5| 6| 7| 8|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

LACRIMAL GLAND                              |                                           M                               |  6       |
ZYMBAL'S GLAND                              |                                           +                               |  6       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |             +                             +                               | 10       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         2|
URINARY BLADDER                             |                                           +                               | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   17
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:17.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7|   U      O|
50MG   F2YR   03     3                      | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | M  +  +  +                                                                |          |
GALLBLADDER                                 | +  M  +  +                                                                |          |
INTESTINE LARGE                             | +  +  A  +                                                                |          |
INTESTINE LARGE,CECUM                       | +  +  A  +                                                                |          |
INTESTINE LARGE,COLON                       | +  +  A  +                                                                |          |
INTESTINE LARGE,RECTUM                      | +  +  A  +                                                                |          |
INTESTINE SMALL                             | +  +  A  +                                                                |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  +                                                                |          |
INTESTINE SMALL,ILEUM                       | +  +  A  +                                                                |          |
INTESTINE SMALL,JEJUNUM                     | +  +  A  +                                                                |          |
  HEMANGIOMA                                |                                                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                        X                                  |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
MESENTERY                                   |                                                                           |          |
PANCREAS                                    | +  +  +  +                                                                |          |
SALIVARY GLANDS                             | +  +  +  +                                                                |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
STOMACH                                     | +  +  A  +                                                                |          |
STOMACH,FORESTOMACH                         | +  +  A  +                                                                |          |
STOMACH,GLANDULAR                           | +  +  A  +                                                                |          |
TONGUE                                      | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +                                                                |          |
BLOOD VESSEL,AORTA                          | +  +  +  +                                                                |          |
HEART                                       | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +                                                                |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +                                                                |          |
ADRENAL GLAND,MEDULLA                       | M  +  +  +                                                                |          |
ISLETS, PANCREATIC                          | +  +  +  +                                                                |          |
PARATHYROID GLAND                           | M  M  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   18
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:17.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7|   U      O|
50MG   F2YR   03     3                      | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
THYROID GLAND                               | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  M  M                                                        +       |          |
OVARY                                       | M  +  +  +        +              +              +     +  +     +     +  + |          |
  CYSTADENOMA                               |                                                                      X    |          |
UTERUS                                      | +  +  +  +  +  +        +  +        +     +     +     +     +     +     + |          |
  LEIOMYOMA                                 |                                                                           |          |
VAGINA                                      | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +                                                                |          |
LYMPH NODE                                  | +  +  +  +           +           +                                        |          |
  LYMPHOMA MALIGNANT,DEEP CERVICAL          |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                  X                                        |          |
  LYMPHOMA MALIGNANT,RENAL                  |                      X           X                                        |          |
LYMPH NODE,MANDIBULAR                       | +  +  M  +           +                                                    |          |
  LYMPHOMA MALIGNANT                        |          X           X                                                    |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +                       +                                        |          |
  LYMPHOMA MALIGNANT                        |                                  X                                        |          |
SPLEEN                                      | +  +  +  +           +           +        +     +     +  +           +    |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |          X           X           X                    X  X                |          |
THYMUS                                      | +  +  +  +                       +                                        |          |
  LYMPHOMA MALIGNANT                        |          X                       X                                        |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  +  +  +                                                                |          |
  ADENOCARCINOMA                            |                                                                           |          |
SKIN                                        | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   19
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:17.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 2| 4| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 6| 7| 1| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 7| 7| 7| 7| 7| 7| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 8| 9| 0| 8| 6| 6| 6| 6| 6| 6| 6| 7| 3| 3| 3| 3| 6| 6| 0| 0| 0| 0| 0| 0| 7|   U      O|
50MG   F2YR   03     3                      | 9| 1| 1| 5| 3| 4| 5| 6| 7| 8| 9| 0| 2| 3| 4| 5| 8| 9| 3| 4| 5| 6| 7| 8| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                                |          |
BONE,FEMUR                                  | +  +  +  +                                                                |          |
BONE,STERNUM                                | +  +  +  +                                                                |          |
SKELETAL MUSCLE                             | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +                                                                |          |
BRAIN,CEREBELLUM                            | +  +  +  +                                                                |          |
BRAIN,CEREBRUM                              | +  +  +  +                                                                |          |
PERIPHERAL NERVE                            | +  +  +  +                                                                |          |
SPINAL CORD                                 | +  +  +  +                                                                |          |
SPINAL CORD,THORACIC                        | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  M  M  +                                                                |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                      X                                         X          |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
NOSE                                        | +  +  +  +                                                                |          |
TRACHEA                                     | M  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +                                                                |          |
HARDERIAN GLAND                             | +  +  +  +                                                                |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
LACRIMAL GLAND                              | +  M  +  +                                                                |          |
ZYMBAL'S GLAND                              | M  M  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +                                                                |          |
URINARY BLADDER                             | +  +  +  +                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   20
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:18.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1|         U      O|
50MG   F2YR   03     3                      | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                      +                                                    |  4       |
GALLBLADDER                                 |                      +                                                    |  4       |
INTESTINE LARGE                             |                      A                                                    |  3       |
INTESTINE LARGE,CECUM                       |                      A                                                    |  3       |
INTESTINE LARGE,COLON                       |                      A                                                    |  3       |
INTESTINE LARGE,RECTUM                      |                      A                                                    |  3       |
INTESTINE SMALL                             |                   +  +                    +                               |  6       |
  LYMPHOMA MALIGNANT                        |                   X                                                       |         1|
INTESTINE SMALL,DUODENUM                    |                      +                                                    |  4       |
INTESTINE SMALL,ILEUM                       |                      A                                                    |  3       |
INTESTINE SMALL,JEJUNUM                     |                      +                    +                               |  5       |
  HEMANGIOMA                                |                                           X                               |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                X                 X                                        |         3|
  LYMPHOMA MALIGNANT                        |                               X                                           |         1|
MESENTERY                                   |                      +                                                    |  1       |
PANCREAS                                    |                      +                                                    |  5       |
SALIVARY GLANDS                             |                      +                                                    |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     |                      +                                                    |  4       |
STOMACH,FORESTOMACH                         |                      +                                                    |  4       |
STOMACH,GLANDULAR                           |                      +                                                    |  4       |
TONGUE                                      |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                      +                                                    |  5       |
BLOOD VESSEL,AORTA                          |                      +                                                    |  5       |
HEART                                       |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                      +                                                    |  5       |
ADRENAL GLAND,CORTEX                        |                      +                                                    |  5       |
ADRENAL GLAND,MEDULLA                       |                      M                                                    |  3       |
ISLETS, PANCREATIC                          |                      +                                                    |  5       |
PARATHYROID GLAND                           |                      +                                                    |  3       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   21
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:18.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1|         U      O|
50MG   F2YR   03     3                      | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
THYROID GLAND                               |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              |                      +                                                    |  4       |
OVARY                                       |       +     +  +     +        +     +     +  +     +  +                   | 21       |
  CYSTADENOMA                               |                                                                           |         1|
UTERUS                                      | +     +  +  +        +  +           +  +        +  +  +  +     +  +       | 29       |
  LEIOMYOMA                                 |                                                                X          |         1|
VAGINA                                      |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                      +                                                    |  5       |
LYMPH NODE                                  |                   +  +                                                    |  8       |
  LYMPHOMA MALIGNANT,DEEP CERVICAL          |                   X                                                       |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         2|
LYMPH NODE,MANDIBULAR                       |                      +                                                    |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LYMPH NODE,MESENTERIC                       |                   +  +                                                    |  7       |
  LYMPHOMA MALIGNANT                        |                   X                                                       |         2|
SPLEEN                                      |    +  +        +  +  +                    +  +                    +       | 19       |
  HEMANGIOSARCOMA                           |                                              X                            |         1|
  LYMPHOMA MALIGNANT                        |       X           X                                                       |         7|
THYMUS                                      |                      M                                                    |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                      +     +                                              |  5       |
  ADENOCARCINOMA                            |                            X                                              |         1|
SKIN                                        |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   22
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:19.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 0| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 7| 8| 8| 8| 8| 8| 1| 4| 4| 4| 4| 4| 4| 4| 0| 1| 1| 1| 1| 1| 1| 1|         U      O|
50MG   F2YR   03     3                      | 8| 9| 0| 1| 2| 3| 4| 0| 0| 1| 2| 3| 4| 5| 6| 9| 0| 1| 2| 3| 4| 5| 6|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

BONE                                        |                      +                                                    |  5       |
BONE,FEMUR                                  |                      +                                                    |  5       |
BONE,STERNUM                                |                      +                                                    |  5       |
SKELETAL MUSCLE                             |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                      +                                                    |  5       |
BRAIN,CEREBELLUM                            |                      +                                                    |  5       |
BRAIN,CEREBRUM                              |                      +                                                    |  5       |
PERIPHERAL NERVE                            |                      +                                                    |  5       |
SPINAL CORD                                 |                      +                                                    |  5       |
SPINAL CORD,THORACIC                        |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                      M                                                    |  1       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        |                      +                                                    |  5       |
TRACHEA                                     |                      +                                                    |  4       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                      +                                                    |  5       |
HARDERIAN GLAND                             |             +        +                                                    |  6       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LACRIMAL GLAND                              |                      +                                                    |  4       |
ZYMBAL'S GLAND                              |                      +                                                    |  3       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                      +                                                    |  5       |
URINARY BLADDER                             |                      +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   23
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:28.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3|   U      O|
100MG  F2YR   04     4                      | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  M  +  +  +  +  M  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X                                                    |          |
INTESTINE LARGE                             | +  +  A  +  A  +  A  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  A  +  A  +  A  +  +  +  +  A  M  A  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | +  +  A  +  A  +  A  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  +  A  +  A  +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL                             | +  +  A  +  A  +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  A  +  A  +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
  POLYP ADENOMATOUS                         |                                                                           |          |
INTESTINE SMALL,ILEUM                       | A  +  A  +  A  +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X                                           |          |
INTESTINE SMALL,JEJUNUM                     | A  +  A  +  A  +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                                   X       |          |
  HEPATOCELLULAR CARCINOMA                  |                                                                      X    |          |
  HISTIOCYTIC SARCOMA                       |       X  X                                                                |          |
  LYMPHOMA MALIGNANT                        |                   X  X        X                                   X       |          |
MESENTERY                                   |                                                                           |          |
PANCREAS                                    | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X                       X                   |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X  X                                                    |          |
STOMACH                                     | +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  A  +  +  A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  PAPILLOMA SQUAMOUS                        |                                                       X                   |          |
STOMACH,GLANDULAR                           | +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   24
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:28.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3|   U      O|
100MG  F2YR   04     4                      | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X                                           |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
ISLETS, PANCREATIC                          | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                            X                                      X       |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  M |          |
PITUITARY GLAND                             | M  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |                         X                 X                       X       |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X                                                    |          |
OVARY                                       | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CYSTADENOMA                               |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                      X                                                    |          |
UTERUS                                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                           X    |          |
  LYMPHOMA MALIGNANT                        |                      X                                                    |          |
VAGINA                                      | +  +  +  M  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |       X                                      X                       X    |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
  POLYP                                     |                                                                X          |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   25
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:28.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3|   U      O|
100MG  F2YR   04     4                      | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                X                                                          |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LYMPH NODE                                  | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                        X                                  |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                        X                                  |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                        X                                  |          |
LYMPH NODE,MANDIBULAR                       | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X  X                 X                             X    |          |
LYMPH NODE,MESENTERIC                       | A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  LYMPHOMA MALIGNANT                        |             X     X  X        X        X                             X    |          |
SPLEEN                                      | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                X                                   X                      |          |
  LYMPHOMA MALIGNANT                        |                   X  X     X  X        X                          X  X    |          |
THYMUS                                      | M  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X                                      X    |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  A  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOCARCINOMA                            |                                              X                            |          |
SKIN                                        | +  +  A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                                                                           |          |
  HEMANGIOSARCOMA                           |                X                                   X                      |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   26
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:28.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3|   U      O|
100MG  F2YR   04     4                      | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
SPINAL CORD                                 | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  M  M  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                       X                 X |          |
  HISTIOCYTIC SARCOMA                       |       X  X                                                                |          |
  LYMPHOMA MALIGNANT                        |                   X  X                 X              X           X       |          |
  OSTEOSARCOMA,METASTATIC,UNCERTAIN PRIMARY |                                     X                                     |          |
      SITE                                  |                                                                           |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  A  +  A  A  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                      X  X                                                 |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LACRIMAL GLAND                              | +  +  A  +  +  +  M  M  +  M  +  +  +  M  +  M  +  +  +  +  +  +  M  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ZYMBAL'S GLAND                              | M  +  M  M  +  M  +  +  +  +  M  +  M  +  +  +  +  +  +  +  M  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X  X                 X                          X       |          |
URINARY BLADDER                             | A  +  M  M  +  +  A  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                      X                                                    |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   27
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:28.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 0| 1| 5| 6| 6| 6| 7| 7| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 8| 6| 3| 3| 9| 0| 5| 5| 5| 5| 1| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 9| 6| 9| 8| 1| 2| 6| 6| 6| 4| 1| 0| 1| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 1| 2| 2| 2| 2| 2| 3| 4| 4| 4| 4| 4| 4| 5| 5| 6| 6| 6| 6|   S      M|
                                            | 0| 2| 6| 7| 8| 9| 0| 2| 2| 2| 7| 8| 0| 2| 9| 9| 9| 9| 9| 0| 0| 2| 2| 3| 3|   U      O|
100MG  F2YR   04     4                      | 3| 0| 6| 8| 2| 9| 1| 4| 5| 6| 3| 6| 3| 8| 5| 6| 7| 8| 9| 0| 1| 8| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   28
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:36.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9|         S      M|
                                            | 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3|         U      O|
100MG  F2YR   04     4                      | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
GALLBLADDER                                 | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 41       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         1|
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 42       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 42       |
  POLYP ADENOMATOUS                         |                X                                                          |         1|
INTESTINE SMALL,ILEUM                       | +  M  +  +  +  +  +  +  M  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                                  X                                        |         2|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                        X                                  |         3|
  LYMPHOMA MALIGNANT                        |                               X                             X             |         6|
MESENTERY                                   |                +                                                          |  1       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         3|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         3|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  PAPILLOMA SQUAMOUS                        |                                                                           |         1|
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         1|
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +       | 45       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   29
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:36.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9|         S      M|
                                            | 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3|         U      O|
100MG  F2YR   04     4                      | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                        X                                  |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 46       |
  ADENOMA                                   |                                                                           |         2|
PARATHYROID GLAND                           | +  +  +  +  +  M  M  +  M  +  +  +  M  +  +  +  +  +  +  +  +  +  M       | 40       |
PITUITARY GLAND                             | +  M  M  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +       | 41       |
  ADENOMA,PARS DISTALIS                     |                      X                                X                   |         5|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  M  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         2|
OVARY                                       | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  CYSTADENOMA                               |                   X                    X                                  |         2|
  HISTIOCYTIC SARCOMA                       |                                        X                                  |         2|
  LYMPHOMA MALIGNANT                        |                               X                                           |         2|
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                             X  X          |         3|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HISTIOCYTIC SARCOMA                       |                                        X                                  |         3|
  LYMPHOMA MALIGNANT                        |                                                                X          |         2|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  HISTIOCYTIC SARCOMA                       |                                        X                                  |         4|
  LYMPHOMA MALIGNANT                        |                                                                X          |         1|
  POLYP                                     |                                                                X          |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   30
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:36.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9|         S      M|
                                            | 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3|         U      O|
100MG  F2YR   04     4                      | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                X          |         2|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |          X                                                                |         2|
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                             X  X          |         6|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +       | 44       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X                 X     X                                           |         9|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |       X  X              X     X                             X             |        12|
THYMUS                                      | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  LYMPHOMA MALIGNANT                        |       X                 X                                      X          |         6|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 44       |
  ADENOCARCINOMA                            |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  FIBROSARCOMA                              | X                                                  X                      |         2|
  HEMANGIOSARCOMA                           |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   31
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:37.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9|         S      M|
                                            | 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3|         U      O|
100MG  F2YR   04     4                      | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                   X        X                                              |         4|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |          X              X                                   X  X          |         9|
  OSTEOSARCOMA,METASTATIC,UNCERTAIN PRIMARY |                                                                           |         1|
      SITE                                  |                                                                           |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         1|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +       | 40       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                         X                                                 |         2|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +       | 40       |
  LYMPHOMA MALIGNANT                        |                                                                X          |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +       | 40       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |          X              X                                   X  X          |         8|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                         X                                      X          |         3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   32
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:37.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9|         S      M|
                                            | 3| 9| 9| 9| 9| 9| 0| 0| 0| 4| 4| 4| 4| 1| 3| 3| 3| 3| 3| 3| 3| 3| 3|         U      O|
100MG  F2YR   04     4                      | 2| 5| 6| 7| 8| 9| 0| 1| 2| 0| 1| 2| 3| 1| 5| 6| 7| 8| 9| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   33
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:39.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|                                                      U      O|
CONTRL F3MTHR 05     5                      | 2| 3| 4| 5| 6| 7| 8| 9|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +                                                    |  8       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +                                                    |  8       |
LIVER                                       | +  +  +  +  +  +  +  +                                                    |  8       |
PANCREAS                                    | +  +  +  +  +  +  +  +                                                    |  8       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH                                     | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +                                                    |  8       |
TONGUE                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  M  +                                                    |  7       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  M  +                                                    |  7       |
HEART                                       | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +                                                    |  8       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +                                                    |  8       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  M                                                    |  7       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
THYROID GLAND                               | +  +  +  +  +  +  +  M                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   34
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:39.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|                                                      U      O|
CONTRL F3MTHR 05     5                      | 2| 3| 4| 5| 6| 7| 8| 9|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

CLITORAL GLAND                              | +  M  +  +  +  +  +  +                                                    |  7       |
OVARY                                       | +  +  +  +  +  +  +  +                                                    |  8       |
UTERUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
VAGINA                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MESENTERIC                       | +  M  +  +  +  +  +  +                                                    |  7       |
SPLEEN                                      | +  +  +  +  +  +  +  +                                                    |  8       |
THYMUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
SKIN                                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +                                                    |  8       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +                                                    |  8       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   35
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:39.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|                                                      U      O|
CONTRL F3MTHR 05     5                      | 2| 3| 4| 5| 6| 7| 8| 9|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  M  M  M  M  +                                                    |  3       |
LUNG                                        | +  +  +  +  +  +  +  +                                                    |  8       |
NOSE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
TRACHEA                                     | +  +  +  +  +  +  +  M                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +                                                    |  8       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
LACRIMAL GLAND                              | +  +  +  +  +  M  +  +                                                    |  7       |
ZYMBAL'S GLAND                              | +  +  +  +  +  M  +  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +                                                    |  8       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   36
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:41.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|                                                      U      O|
CONTRL F6MTHR 06     6                      | 1| 2| 3| 4| 5| 6| 7| 8|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | M  +  +  +  +  +  +  +                                                    |  7       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +                                                    |  8       |
LIVER                                       | +  +  +  +  +  +  +  +                                                    |  8       |
PANCREAS                                    | +  +  +  +  +  +  +  +                                                    |  8       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH                                     | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +                                                    |  8       |
TONGUE                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  M  +  +  +                                                    |  7       |
BLOOD VESSEL,AORTA                          | +  +  +  +  M  +  +  +                                                    |  7       |
HEART                                       | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +                                                    |  8       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +                                                    |  8       |
PARATHYROID GLAND                           | +  M  M  M  +  M  +  +                                                    |  4       |
PITUITARY GLAND                             | M  +  M  +  M  +  M  M                                                    |  3       |
THYROID GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   37
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:41.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|                                                      U      O|
CONTRL F6MTHR 06     6                      | 1| 2| 3| 4| 5| 6| 7| 8|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  +                                                    |  8       |
OVARY                                       | +  +  +  +  +  +  +  +                                                    |  8       |
UTERUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
VAGINA                                      | +  +  +  +  M  +  +  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +                                                    |  8       |
SPLEEN                                      | +  +  +  +  +  +  +  +                                                    |  8       |
THYMUS                                      | +  +  +  +  M  +  +  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
SKIN                                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +                                                    |  8       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +                                                    |  8       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   38
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:42.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|                                                      U      O|
CONTRL F6MTHR 06     6                      | 1| 2| 3| 4| 5| 6| 7| 8|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  M  +  M  M  +  M  M                                                    |  3       |
LUNG                                        | +  +  +  +  +  +  +  +                                                    |  8       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              | X                                                                         |         1|
NOSE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
TRACHEA                                     | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +                                                    |  8       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
LACRIMAL GLAND                              | +  +  M  +  M  +  +  +                                                    |  6       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  M  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +                                                    |  8       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   39
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:44.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 3| 3| 3| 3| 3| 3| 3|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 4| 4| 4| 4| 4| 4| 4| 4|                                                      U      O|
CONTRL F12MTHR07     7                      | 0| 1| 2| 3| 4| 5| 6| 7|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +                                                    |  8       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,COLON                       | +  +  +  +  M  +  +  +                                                    |  7       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +                                                    |  8       |
LIVER                                       | +  +  +  +  +  +  +  +                                                    |  8       |
MESENTERY                                   |                +                                                          |  1       |
  YOLK SAC CARCINOMA,METASTATIC,OVARY       |                X                                                          |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +                                                    |  8       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH                                     | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +                                                    |  8       |
TONGUE                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +                                                    |  8       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +                                                    |  8       |
HEART                                       | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | M  +  +  +  +  +  +  +                                                    |  7       |
ADRENAL GLAND,CORTEX                        | M  +  +  +  +  +  +  +                                                    |  7       |
ADRENAL GLAND,MEDULLA                       | M  +  +  +  +  +  +  +                                                    |  7       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +                                                    |  8       |
PARATHYROID GLAND                           | +  M  M  M  +  +  M  M                                                    |  3       |
PITUITARY GLAND                             | M  M  +  +  +  M  +  +                                                    |  5       |
THYROID GLAND                               | +  M  +  +  +  +  M  +                                                    |  6       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   40
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:44.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 3| 3| 3| 3| 3| 3| 3|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 4| 4| 4| 4| 4| 4| 4| 4|                                                      U      O|
CONTRL F12MTHR07     7                      | 0| 1| 2| 3| 4| 5| 6| 7|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

CLITORAL GLAND                              | M  +  +  +  +  M  +  +                                                    |  6       |
OVARY                                       | +  +  +  +  +  +  +  +                                                    |  8       |
  YOLK SAC CARCINOMA                        |                X                                                          |         1|
UTERUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
VAGINA                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +                                                    |  8       |
SPLEEN                                      | +  +  +  +  +  +  +  +                                                    |  8       |
THYMUS                                      | +  +  M  +  +  +  +  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
SKIN                                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +                                                    |  8       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +                                                    |  8       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   41
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:44.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 3| 3| 3| 3| 3| 3| 3|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 4| 4| 4| 4| 4| 4| 4| 4|                                                      U      O|
CONTRL F12MTHR07     7                      | 0| 1| 2| 3| 4| 5| 6| 7|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | M  +  +  +  +  +  +  M                                                    |  6       |
LUNG                                        | +  +  +  +  +  +  +  +                                                    |  8       |
NOSE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
TRACHEA                                     | +  M  +  +  +  +  M  +                                                    |  6       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +                                                    |  8       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
LACRIMAL GLAND                              | M  +  +  +  +  +  +  +                                                    |  7       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +                                                    |  8       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   42
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:51.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2|   U      O|
100MG  F3MTH  08     8                      | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +  +  A  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
INTESTINE LARGE                             | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X                                           |          |
INTESTINE LARGE,COLON                       | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,ILEUM                       | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  M  +  + |          |
INTESTINE SMALL,JEJUNUM                     | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                        X                                  |          |
  LYMPHOMA MALIGNANT                        |                   X           X     X        X                            |          |
MESENTERY                                   |                                                                           |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
STOMACH                                     | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  A  A  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  M  M  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | +  M  M  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,SPINDLE CELL                      |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   43
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:51.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2|   U      O|
100MG  F3MTH  08     8                      | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                              X                            |          |
PARATHYROID GLAND                           | +  +  +  M  +  +  +  +  +  +  +  M  +  M  M  +  +  +  +  M  M  +  +  M  M |          |
PITUITARY GLAND                             | +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,FOLLICULAR CELL                   |                                                          X                |          |
  LYMPHOMA MALIGNANT                        |                                              X                            |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
  TERATOMA BENIGN                           |                                                                           |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  POLYP                                     |                                                                         X |          |
VAGINA                                      | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                        X                                  |          |
  LYMPHOMA MALIGNANT                        |                               X                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |                               X                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                              X                            |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X     X        X                            |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X     X        X                            |          |
THYMUS                                      | +  M  +  M  M  +  M  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X     X                                     |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   44
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:51.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2|   U      O|
100MG  F3MTH  08     8                      | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  + |          |
  ADENOCARCINOMA                            |                                                                           |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                              X                            |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X                                           |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X                         |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                          X                |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |             X                                                             |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   45
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:52.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 5| 2| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 4| 6| 5| 9| 5| 5| 5| 5| 5| 5| 5| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 4| 0| 2| 2| 8| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 2| 2| 2| 3| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7|   S      M|
                                            | 6| 6| 7| 8| 2| 1| 1| 1| 1| 1| 2| 2| 2| 4| 4| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2|   U      O|
100MG  F3MTH  08     8                      | 5| 7| 5| 0| 2| 5| 6| 7| 8| 9| 0| 1| 2| 8| 9| 0| 1| 2| 0| 1| 2| 3| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                X          |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
LACRIMAL GLAND                              | +  +  M  +  M  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |                                              X                            |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X           X              X                            |          |
URINARY BLADDER                             | +  +  +  A  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                               X              X                            |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   46
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:56.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4|                                 U      O|
100MG  F3MTH  08     8                      | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  M  +  +  M  +  M  +  M                               | 36       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL,ILEUM                       | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 35       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  HEPATOCELLULAR ADENOMA                    |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |          X     X                                                          |         6|
MESENTERY                                   |                      +                                                    |  1       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                X                                                          |         3|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ADENOMA,SPINDLE CELL                      |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   47
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:56.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4|                                 U      O|
100MG  F3MTH  08     8                      | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PARATHYROID GLAND                           | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 31       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +                               | 36       |
  ADENOMA,PARS DISTALIS                     |    X                             X     X                                  |         3|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ADENOMA,FOLLICULAR CELL                   |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +                               | 37       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |          X     X                                                          |         4|
  TERATOMA BENIGN                           |                         X                                                 |         1|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  POLYP                                     |                                                                           |         1|
VAGINA                                      | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         3|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |          X     X                                                          |         4|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |          X     X                                                          |         6|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |          X                 X              X                               |         7|
THYMUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +                               | 33       |
  LYMPHOMA MALIGNANT                        |          X     X                                                          |         4|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   48
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:56.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4|                                 U      O|
100MG  F3MTH  08     8                      | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +                               | 36       |
  ADENOCARCINOMA                            |                                        X                                  |         1|
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  FIBROSARCOMA                              |                      X                                                    |         2|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
PERIPHERAL NERVE                            | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                           X                               |         2|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                            X                                              |         3|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   49
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:20:56.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 7| 7| 7| 7| 7| 7| 7| 4| 4| 4| 4| 4| 4| 4| 4|                                 U      O|
100MG  F3MTH  08     8                      | 3| 4| 5| 6| 7| 8| 9| 2| 3| 4| 5| 6| 7| 8| 9|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M                               | 38       |
  ADENOMA                                   |                X                                                          |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LACRIMAL GLAND                              | +  +  +  M  +  +  +  +  +  +  +  +  +  M  +                               | 33       |
  LYMPHOMA MALIGNANT                        |                X                                                          |         2|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +                               | 38       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |          X     X           X                                              |         6|
URINARY BLADDER                             | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   50
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:05.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1|   U      O|
100MG  F6MTH  09     9                      | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
GALLBLADDER                                 | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
INTESTINE LARGE                             | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
INTESTINE LARGE,RECTUM                      | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,ILEUM                       | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,JEJUNUM                     | +  A  +  +  +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
  HEPATOCELLULAR ADENOMA                    |                                              X                            |          |
  HEPATOCELLULAR CARCINOMA                  |                                                                         X |          |
  HISTIOCYTIC SARCOMA                       |                               X                                           |          |
  LYMPHOMA MALIGNANT                        |       X                 X                       X                         |          |
MESENTERY                                   |                   +                                                       |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                   X                                                       |          |
PANCREAS                                    | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                   X  X                                                    |          |
  LYMPHOMA MALIGNANT                        |                         X           X  X                                  |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                 X                       X                         |          |
STOMACH                                     | +  A  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  A  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  A  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   51
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:05.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1|   U      O|
100MG  F6MTH  09     9                      | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

  LYMPHOMA MALIGNANT                        |                         X                                                 |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  A  +  +  +  +  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  A  +  +  +  +  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  A  +  +  +  +  +  M  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  A  +  +  +  +  A  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PARATHYROID GLAND                           | +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  M |          |
  ADENOMA                                   |                                                                      X    |          |
PITUITARY GLAND                             | M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |       X                                                                   |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA,FOLLICULAR CELL                   |                                                 X                         |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                      +                                                    |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  M  M  M  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CYSTADENOMA                               |                               X                                X          |          |
  FIBROSARCOMA,METASTATIC,SKIN,PERIOVARIAN T|                      X                                                    |          |
      ISSUE                                 |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                 X                                                 |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                 X                         |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
  POLYP                                     |                            X                                              |          |
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   52
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:05.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1|   U      O|
100MG  F6MTH  09     9                      | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |                         X                                                 |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                         X                                                 |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                         X                       X                         |          |
  LYMPHOMA MALIGNANT,THORACIC               |       X                                                                   |          |
  SQUAMOUS CELL CARCINOMA,METASTATIC,SKIN,LU| X                                                                         |          |
      MBAR                                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X     X           X                       X                         |          |
LYMPH NODE,MESENTERIC                       | +  A  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |       X                 X                       X                         |          |
SPLEEN                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |       X     X           X           X  X        X                         |          |
THYMUS                                      | +  M  M  M  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |                         X                       X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOCARCINOMA                            |    X                                                                      |          |
  LYMPHOMA MALIGNANT                        |       X                 X                                                 |          |
SKIN                                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                   X  X                                                    |          |
  LYMPHOMA MALIGNANT                        |       X                                         X                         |          |
  SQUAMOUS CELL CARCINOMA                   | X                                                                         |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   53
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:05.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1|   U      O|
100MG  F6MTH  09     9                      | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        |       X                 X                                                 |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                 X                                                 |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  +  M  +  M  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOCARCINOMA,METASTATIC,MAMMARY GLAND   |    X                                                                      |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                     X  X                 X  X             |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |       X                 X                       X                         |          |
  SQUAMOUS CELL CARCINOMA,METASTATIC,SKIN   | X                                                                         |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  A  A  +  +  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                  X                                        |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
LACRIMAL GLAND                              | +  +  +  M  +  +  +  +  M  +  +  M  +  +  M  +  +  +  M  +  +  +  M  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                         X                         |          |
ZYMBAL'S GLAND                              | M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   54
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:05.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 0| 4| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 8| 9| 7| 7| 2| 8| 8| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 0| 5| 4| 6| 0| 4| 2| 1| 5| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 2| 2| 2| 3| 3| 3| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 7| 9| 9| 6| 7| 8| 1| 2| 9| 0| 1| 1| 1| 1| 1| 4| 4| 4| 4| 4| 4| 4| 1| 1| 1|   U      O|
100MG  F6MTH  09     9                      | 7| 2| 4| 4| 0| 8| 3| 1| 0| 9| 0| 1| 2| 3| 4| 1| 2| 3| 4| 5| 6| 7| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM

KIDNEY                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                 X              X        X                         |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                         X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   55
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:10.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4|                                 U      O|
100MG  F6MTH  09     9                      | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
GALLBLADDER                                 | +  +  +  +  M  +  +  +  +  +  M  +  +  +  +                               | 36       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  HEPATOCELLULAR ADENOMA                    |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X  X  X     X                                                       |         7|
MESENTERY                                   |    +                                                                      |  2       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |             X     X                                                       |         5|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +  +  +  +  +  +  +  +  +  +  M  +  +                               | 35       |
BLOOD VESSEL,AORTA                          | M  M  +  +  +  +  +  +  +  +  +  +  M  +  +                               | 35       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   56
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:10.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4|                                 U      O|
100MG  F6MTH  09     9                      | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
CARDIOVASCULAR SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
PARATHYROID GLAND                           | +  +  +  +  +  +  M  M  +  +  +  +  +  +  +                               | 33       |
  ADENOMA                                   |                                                                           |         1|
PITUITARY GLAND                             | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +                               | 36       |
  ADENOMA,PARS DISTALIS                     |                                                                           |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ADENOMA,FOLLICULAR CELL                   |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                           |  1       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  M  +  +  +  +  M  +  +                               | 33       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
OVARY                                       | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +                               | 39       |
  CYSTADENOMA                               |                                                                           |         2|
  FIBROSARCOMA,METASTATIC,SKIN,PERIOVARIAN T|                                                                           |         1|
      ISSUE                                 |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |          X                 X     X                                        |         4|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  POLYP                                     |                                                                           |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   57
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:11.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4|                                 U      O|
100MG  F6MTH  09     9                      | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |       X                    X                                              |         2|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                            X                                              |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                            X                                              |         3|
  LYMPHOMA MALIGNANT,THORACIC               |                                                                           |         1|
  SQUAMOUS CELL CARCINOMA,METASTATIC,SKIN,LU|                                                                           |         1|
      MBAR                                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |                            X     X                                        |         6|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X     X              X                                              |         6|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |          X  X     X        X     X                                        |        11|
THYMUS                                      | M  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 31       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X     X              X                                        |         5|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +                               | 38       |
  ADENOCARCINOMA                            |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  FIBROSARCOMA                              |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
  SQUAMOUS CELL CARCINOMA                   |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   58
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:11.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4|                                 U      O|
100MG  F6MTH  09     9                      | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +                               | 34       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ADENOCARCINOMA,METASTATIC,MAMMARY GLAND   |                                                                           |         1|
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         4|
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X                                                             |         4|
  SQUAMOUS CELL CARCINOMA,METASTATIC,SKIN   |                                                                           |         1|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 34       |
HARDERIAN GLAND                             | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +                               | 38       |
  ADENOMA                                   |       X                                                                   |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LACRIMAL GLAND                              | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +                               | 33       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
ZYMBAL'S GLAND                              | +  +  M  M  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   59
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:11.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 9| 9| 9| 9| 9| 9| 9| 9|                                 S      M|
                                            | 1| 1| 9| 9| 9| 9| 9| 3| 3| 3| 3| 3| 3| 4| 4|                                 U      O|
100MG  F6MTH  09     9                      | 8| 9| 1| 2| 3| 4| 5| 4| 5| 6| 7| 8| 9| 0| 1|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |       X     X     X                                                       |         7|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   60
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:17.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1|   U      O|
100MG  F12MTH 10    10                      | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | A  +  A  +  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | A  A  A  A  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | A  +  A  +  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | A  +  A  M  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
INTESTINE SMALL                             | A  A  A  A  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | A  A  A  A  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,ILEUM                       | A  A  A  A  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
INTESTINE SMALL,JEJUNUM                     | A  A  A  A  A  A  A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                             X        X    |          |
  HEPATOCELLULAR CARCINOMA                  |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |    X                                                  X     X     X  X    |          |
PANCREAS                                    | +  +  A  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                             X        X    |          |
STOMACH                                     | +  +  A  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | A  +  A  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  A  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  A  M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  A  M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
ADRENAL GLAND,MEDULLA                       | +  +  A  M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   61
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:18.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1|   U      O|
100MG  F12MTH 10    10                      | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  +  A  +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
PITUITARY GLAND                             | +  +  A  M  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  M  +  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  A  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  M  +  +  M  + |          |
OVARY                                       | +  +  M  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |    X                                                              X     X |          |
  TERATOMA BENIGN                           |    X                                                                      |          |
UTERUS                                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
  SARCOMA STROMAL                           |    X                                                                      |          |
VAGINA                                      | +  A  A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                   X                 X                                     |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
  LYMPHOMA MALIGNANT,THORACIC               |    X                                                                      |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                            X           X        X  X |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |    X                                            X           X     X  X  X |          |
SPLEEN                                      | +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |    X                                                                 X    |          |
THYMUS                                      | +  +  A  M  +  M  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |    X                                            X           X             |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   62
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:18.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1|   U      O|
100MG  F12MTH 10    10                      | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  A  +  M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOACANTHOMA                            |                X                                                          |          |
SKIN                                        | +  +  M  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                      X    |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  M  A  M  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOACANTHOMA,METASTATIC,MAMMARY GLAND   |                X                                                          |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                            X                             X     X          |          |
  HISTIOCYTIC SARCOMA                       |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                 X                          X           X        X    |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  A  A  +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA,RETROBULBAR           |                   X                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   63
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:18.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 7| 7| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 9| 9| 1| 1| 3| 6| 9| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 3| 1| 6| 9| 9| 8| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 1| 1| 2| 3| 3| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7|   S      M|
                                            | 5| 9| 0| 0| 7| 1| 1| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3| 3| 3| 3| 4| 0| 1| 1|   U      O|
100MG  F12MTH 10    10                      | 8| 8| 2| 5| 6| 4| 6| 2| 3| 4| 5| 6| 7| 8| 3| 4| 5| 6| 7| 8| 9| 0| 9| 0| 1|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

HARDERIAN GLAND                             | +  +  A  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +  M  +  +  +  +  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |                                                             X        X    |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  M  M  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                        X     X  X    |          |
URINARY BLADDER                             | +  +  A  +  A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                             X        X  X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   64
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:22.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8|                                 S      M|
                                            | 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5|                                 U      O|
100MG  F12MTH 10    10                      | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +                               | 36       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 34       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 32       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 34       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 32       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 33       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 33       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 31       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 32       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  HEPATOCELLULAR ADENOMA                    |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA                  |          X                          X                                     |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |             X        X     X                                              |         8|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 35       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  M  +  +  +  +  +  +  M  +  +  +  +  +                               | 37       |
BLOOD VESSEL,AORTA                          | +  +  M  +  +  +  +  +  +  M  +  +  +  +  +                               | 37       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   65
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:22.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8|                                 S      M|
                                            | 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5|                                 U      O|
100MG  F12MTH 10    10                      | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +                               | 36       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  M  +  +  +  +  M  +  M                               | 33       |
  ADENOMA,PARS DISTALIS                     |       X                                                                   |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  M  +  +  +  +  +  +  +  +  +  +  +  +  M                               | 33       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                                           |         3|
  TERATOMA BENIGN                           |                                                                           |         1|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  SARCOMA STROMAL                           |                                                                           |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 37       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  LYMPHOMA MALIGNANT,THORACIC               |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  LYMPHOMA MALIGNANT                        | X                    X                                                    |         7|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                      X           X                                        |         8|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
  HEMANGIOSARCOMA                           |                                        X                                  |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X  X        X        X     X     X                                        |         8|
THYMUS                                      | +  M  +  +  +  +  +  M  M  +  +  +  M  +  +                               | 30       |
  LYMPHOMA MALIGNANT                        | X                                X                                        |         5|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   66
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:22.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8|                                 S      M|
                                            | 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5|                                 U      O|
100MG  F12MTH 10    10                      | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +                               | 36       |
  ADENOACANTHOMA                            |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +                               | 34       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
  ADENOACANTHOMA,METASTATIC,MAMMARY GLAND   |                                                                           |         1|
  ALVEOLAR/BRONCHIOLAR ADENOMA              |    X                          X     X  X                                  |         7|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X           X        X                                                    |         8|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 40       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 39       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 35       |
  HISTIOCYTIC SARCOMA,RETROBULBAR           |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   67
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:22.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                 S      U|
FEMALE                      CARCASS ID      | 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8|                                 S      M|
                                            | 1| 1| 1| 8| 8| 8| 8| 8| 9| 4| 4| 4| 5| 5| 5|                                 U      O|
100MG  F12MTH 10    10                      | 2| 3| 4| 5| 6| 7| 8| 9| 0| 7| 8| 9| 0| 1| 2|                                 E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  ADENOMA                                   |                   X           X           X                               |         3|
LACRIMAL GLAND                              | M  M  +  +  +  +  M  +  +  M  +  +  +  +  +                               | 32       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
ZYMBAL'S GLAND                              | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 38       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         5|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +                               | 36       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   68
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:29.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|   S      M|
                                            | 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6|   U      O|
CONTRL FS-2YR 11    11                      | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  M  +  +  + |          |
INTESTINE LARGE                             | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                X                                                          |          |
INTESTINE LARGE,COLON                       | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | +  A  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  A  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,ILEUM                       | +  A  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  A  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                   X              X                                        |          |
  HEPATOCELLULAR CARCINOMA                  |    X                                                           X          |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  LYMPHOMA MALIGNANT                        |       X        X                                X           X             |          |
MESENTERY                                   |                                                          +                |          |
PANCREAS                                    | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
STOMACH                                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  SQUAMOUS CELL CARCINOMA                   |                                                                           |          |
STOMACH,GLANDULAR                           | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   69
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:29.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|   S      M|
                                            | 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6|   U      O|
CONTRL FS-2YR 11    11                      | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
ADRENAL GLAND,MEDULLA                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | M  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  M  +  +  +  M |          |
PITUITARY GLAND                             | M  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  M  M  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  +  M  M  + |          |
OVARY                                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                                                           |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  POLYP                                     |                                                                           |          |
VAGINA                                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                         X                         |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                X                                                          |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                X                                                          |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                X                                X                         |          |
SPLEEN                                      | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X        X                                X           X             |          |
THYMUS                                      | M  +  M  +  M  M  +  M  M  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   70
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:29.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|   S      M|
                                            | 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6|   U      O|
CONTRL FS-2YR 11    11                      | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |             X                                                             |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  M  M  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                    X                      |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,MULTIPLE     |                                                                           |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                X        X                         |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   71
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:29.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 5| 5| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 8| 6| 9| 6| 1| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 9| 1| 1| 8| 7| 3| 5| 5| 5| 5| 6| 6| 6| 6| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 2| 2| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|   S      M|
                                            | 8| 9| 7| 8| 0| 2| 9| 9| 9| 9| 3| 3| 3| 3| 4| 4| 4| 7| 7| 7| 6| 6| 6| 6| 6|   U      O|
CONTRL FS-2YR 11    11                      | 3| 3| 7| 7| 8| 9| 5| 6| 7| 8| 1| 2| 3| 4| 0| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  A  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                          X                |          |
  CARCINOMA                                 |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
LACRIMAL GLAND                              | +  +  +  +  M  M  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                             X             |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
URINARY BLADDER                             | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |          X                                                                |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   72
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:35.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         S      M|
                                            | 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0|         U      O|
CONTRL FS-2YR 11    11                      | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +       | 45       |
GALLBLADDER                                 | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         2|
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                            X                                              |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  M  +       | 42       |
  LYMPHOMA MALIGNANT                        |                            X                                              |         1|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                                           X                               |         3|
  HEPATOCELLULAR CARCINOMA                  |                                                 X                         |         3|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                            X                                              |         5|
MESENTERY                                   |                                                 +                         |  2       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                            X                                              |         2|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  SQUAMOUS CELL CARCINOMA                   |                                  X                                        |         1|
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   73
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:35.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         S      M|
                                            | 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0|         U      O|
CONTRL FS-2YR 11    11                      | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ADRENAL GLAND,CORTEX                        | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
PARATHYROID GLAND                           | +  +  +  +  M  +  +  +  +  M  +  M  +  +  +  M  +  +  +  +  +  +  +       | 38       |
PITUITARY GLAND                             | +  +  +  +  +  M  M  M  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +       | 40       |
  ADENOMA,PARS DISTALIS                     |                                        X                                  |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M       | 38       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                            X                                              |         1|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  POLYP                                     |                                                 X                         |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         3|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         2|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |             X              X                                              |         4|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |             X              X                          X                   |         7|
THYMUS                                      | +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M       | 38       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   74
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:36.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         S      M|
                                            | 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0|         U      O|
CONTRL FS-2YR 11    11                      | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |             X                                                             |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROSARCOMA                              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |    X                                                     X                |         3|
  ALVEOLAR/BRONCHIOLAR ADENOMA,MULTIPLE     |                                           X                               |         1|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                      X                                                    |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                      X                                                    |         1|
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   75
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:36.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9|         S      M|
                                            | 6| 4| 4| 4| 5| 6| 6| 7| 1| 1| 1| 1| 2| 2| 2| 2| 9| 9| 9| 9| 9| 0| 0|         U      O|
CONTRL FS-2YR 11    11                      | 6| 7| 8| 9| 0| 8| 9| 0| 6| 7| 8| 9| 4| 5| 6| 7| 5| 6| 7| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |                                                                           |         1|
  CARCINOMA                                 |                      X                                                    |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LACRIMAL GLAND                              | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                            X                                              |         2|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   76
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:39.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6|   S      M|
                                            | 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5|   U      O|
10MG   FS-2YR 12    12                      | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
GALLBLADDER                                 | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
INTESTINE LARGE                             | A  +  +  +  +  +  +                                                       |          |
INTESTINE LARGE,CECUM                       | A  +  A  +  +  +  +                                                       |          |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +                                                       |          |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +                                                       |          |
INTESTINE SMALL                             | A  +  A  +  +  +  +                    +  +                               |          |
INTESTINE SMALL,DUODENUM                    | A  +  A  +  +  +  +                    +                                  |          |
  LYMPHOMA MALIGNANT                        |                                        X                                  |          |
INTESTINE SMALL,ILEUM                       | A  +  A  +  +  +  +                                                       |          |
INTESTINE SMALL,JEJUNUM                     | A  +  A  +  +  +  +                       +                               |          |
  LYMPHOMA MALIGNANT                        |                                           X                               |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                            X                                              |          |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        | X  X     X                             X  X                    X        X |          |
MESENTERY                                   |                               +        +                 +        +       |          |
  SARCOMA                                   |                                                                   X       |          |
PANCREAS                                    | A  +  +  +  +  +  +                    +                                  |          |
  LYMPHOMA MALIGNANT                        |    X     X                                                                |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
STOMACH                                     | A  +  +  +  +  +  +                                                       |          |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X     X                                                                |          |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X     X                                                                |          |
TONGUE                                      | +  +  +  +  +  +  +                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  M  +  +  +  +  +                                                       |          |
BLOOD VESSEL,AORTA                          | +  M  +  +  +  +  +                                                       |          |
HEART                                       | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   77
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:39.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6|   S      M|
                                            | 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5|   U      O|
10MG   FS-2YR 12    12                      | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +                          +                            |          |
  FIBROSARCOMA,METASTATIC,SKIN              |                                              X                            |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +                                                       |          |
  HISTIOCYTIC SARCOMA                       |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +                                                       |          |
ISLETS, PANCREATIC                          | A  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
PARATHYROID GLAND                           | +  +  +  +  +  +  +                                                       |          |
PITUITARY GLAND                             | A  +  +  +  M  +  M                                                       |          |
THYROID GLAND                               | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
OVARY                                       | +  +  +  +  +  +  +  +     +  +           +  +                    +  +    |          |
  CYSTADENOMA                               |                                           X                               |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
  SARCOMA                                   |                                                                   X       |          |
UTERUS                                      | +  +  +  +  +  +  +           +  +                 +     +  +  +     +  + |          |
  LEIOMYOMA                                 |                                                    X                      |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
VAGINA                                      | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X     X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
LYMPH NODE                                  | +  +  +  +  +  +  +                                               +     + |          |
  LYMPHOMA MALIGNANT,AXILLARY               |    X                                                                      |          |
  LYMPHOMA MALIGNANT,INGUINAL               | X                                                                         |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                         X |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +                                                       |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   78
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:39.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6|   S      M|
                                            | 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5|   U      O|
10MG   FS-2YR 12    12                      | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  M  +  +                                               +       |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
  SARCOMA                                   |                                                                   X       |          |
SPLEEN                                      | +  +  +  +  +  +  +        +              +     +     +     +  +        + |          |
  HEMANGIOSARCOMA                           |                   X                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X     X                 X              X     X           X  X        X |          |
THYMUS                                      | +  +  +  M  M  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
  SARCOMA,METASTATIC,SKIN                   |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | A  +  +  M  +  +  +                                                       |          |
  ADENOCARCINOMA                            |                X                                                          |          |
  FIBROUS HISTIOCYTOMA                      |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKIN                                        | A  +  +  +  +  +  +                          +                            |          |
  FIBROSARCOMA                              |                                              X                            |          |
  HEMANGIOSARCOMA,METASTATIC,UNCERTAIN PRIMA|                   X                                                       |          |
      RY SITE                               |                                                                           |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
  SARCOMA                                   |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +                                                       |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
BONE,STERNUM                                | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   79
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:39.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6|   S      M|
                                            | 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5|   U      O|
10MG   FS-2YR 12    12                      | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +                                                       |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
SPINAL CORD                                 | +  +  +  +  +  +  +                                                       |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  M  M  +  M  M  +                                                       |          |
LUNG                                        | +  +  +  +  +  +  +                                                       |          |
  FIBROUS HISTIOCYTOMA                      |             X                                                             |          |
  LYMPHOMA MALIGNANT                        | X  X     X                                                                |          |
  SARCOMA,METASTATIC,SKIN                   |       X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
TRACHEA                                     | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A  +  A  A  +  +  +                                                       |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +                                                     + |          |
  ADENOMA                                   |                                                                         X |          |
  LYMPHOMA MALIGNANT                        | X  X                                                                      |          |
LACRIMAL GLAND                              | +  M  M  M  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
ZYMBAL'S GLAND                              | M  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   80
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:40.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 6| 7| 5| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 6| 6| 9| 0| 8| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 3| 8| 5| 8| 8| 2| 7| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6|   S      M|
                                            | 6| 8| 8| 9| 0| 8| 8| 7| 7| 7| 7| 7| 7| 7| 7| 3| 3| 3| 3| 7| 7| 7| 5| 5| 5|   U      O|
10MG   FS-2YR 12    12                      | 9| 5| 6| 6| 0| 3| 7| 1| 2| 3| 4| 5| 6| 7| 8| 6| 7| 8| 9| 0| 1| 2| 4| 5| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X     X                                                                |          |
URETER                                      |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
URINARY BLADDER                             | +  +  +  +  +  +  +                                                       |          |
  LYMPHOMA MALIGNANT                        | X  X     X                                                                |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   81
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:41.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9|         U      O|
10MG   FS-2YR 12    12                      | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                              M                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
GALLBLADDER                                 |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
INTESTINE LARGE                             |                                              +                            |  7       |
INTESTINE LARGE,CECUM                       |                                              +                            |  6       |
INTESTINE LARGE,COLON                       |                                              +                            |  7       |
INTESTINE LARGE,RECTUM                      |                                              +                            |  7       |
INTESTINE SMALL                             |                                              +                            |  8       |
INTESTINE SMALL,DUODENUM                    |                                              +                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE SMALL,ILEUM                       |                                              +                            |  6       |
INTESTINE SMALL,JEJUNUM                     |                                              +                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                               X        X                                  |         3|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                  X           X  X                         |        10|
MESENTERY                                   |                                                                           |  4       |
  SARCOMA                                   |                                                                           |         1|
PANCREAS                                    |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SALIVARY GLANDS                             |                                              +  +                         |  9       |
  LYMPHOMA MALIGNANT                        |                                                 X                         |         3|
STOMACH                                     |                                              +                            |  7       |
STOMACH,FORESTOMACH                         |                                              +                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
STOMACH,GLANDULAR                           |                                              +                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
TONGUE                                      |                                              +                            |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                              +                            |  7       |
BLOOD VESSEL,AORTA                          |                                              +                            |  7       |
HEART                                       |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   82
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:41.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9|         U      O|
10MG   FS-2YR 12    12                      | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                              +                            |  9       |
  FIBROSARCOMA,METASTATIC,SKIN              |                                                                           |         1|
ADRENAL GLAND,CORTEX                        |                                              +                            |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         3|
ADRENAL GLAND,MEDULLA                       |                                              +                            |  8       |
ISLETS, PANCREATIC                          |                                              +                            |  7       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PARATHYROID GLAND                           |                                              M                            |  7       |
PITUITARY GLAND                             |                                              M                            |  4       |
THYROID GLAND                               |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
OVARY                                       | +  +  +        +     +     +  +     +  +  +  +  +     +     +             | 28       |
  CYSTADENOMA                               |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
  SARCOMA                                   |                                                                           |         1|
UTERUS                                      | +  +           +  +     +  +  +  +        +  +  +           +  +  +       | 29       |
  LEIOMYOMA                                 |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
VAGINA                                      |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                              X                            |         3|
LYMPH NODE                                  |             +                    +  +        +  +     +                   | 15       |
  LYMPHOMA MALIGNANT,AXILLARY               |                                                                           |         1|
  LYMPHOMA MALIGNANT,INGUINAL               |                                                 X                         |         2|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                              X                            |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                              X                            |         2|
LYMPH NODE,MANDIBULAR                       |             +                                +                            |  9       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   83
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:41.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9|         U      O|
10MG   FS-2YR 12    12                      | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |             X                                X                            |         4|
LYMPH NODE,MESENTERIC                       |                                  +           +  +     +                   | 11       |
  LYMPHOMA MALIGNANT                        |                                  X           X  X     X                   |         6|
  SARCOMA                                   |                                                                           |         1|
SPLEEN                                      |             +           +     +  +           +  +                         | 20       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                               X  X           X  X                         |        13|
THYMUS                                      |                                              +                            |  6       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
  SARCOMA,METASTATIC,SKIN                   |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                              +                            |  6       |
  ADENOCARCINOMA                            |                                                                           |         1|
  FIBROUS HISTIOCYTOMA                      |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKIN                                        |                                              +                            |  8       |
  FIBROSARCOMA                              |                                                                           |         1|
  HEMANGIOSARCOMA,METASTATIC,UNCERTAIN PRIMA|                                                                           |         1|
      RY SITE                               |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  SARCOMA                                   |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                              +                            |  8       |
BONE,FEMUR                                  |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
BONE,STERNUM                                |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SKELETAL MUSCLE                             |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   84
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:41.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9|         U      O|
10MG   FS-2YR 12    12                      | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       |                                              +                            |  8       |
BRAIN,CEREBELLUM                            |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
BRAIN,CEREBRUM                              |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
PERIPHERAL NERVE                            |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SPINAL CORD                                 |                                              +                            |  8       |
SPINAL CORD,THORACIC                        |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                              +                            |  4       |
LUNG                                        |                                              +                            |  8       |
  FIBROUS HISTIOCYTOMA                      |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         4|
  SARCOMA,METASTATIC,SKIN                   |                                                                           |         1|
NOSE                                        |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TRACHEA                                     |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                                              +                            |  5       |
HARDERIAN GLAND                             |                +                             +                            | 10       |
  ADENOMA                                   |                X                                                          |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
LACRIMAL GLAND                              |                                              +                            |  5       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              |                                              M                            |  6       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   85
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:41.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 1| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|         S      M|
                                            | 5| 5| 5| 6| 4| 4| 4| 6| 6| 5| 5| 5| 5| 5| 5| 8| 8| 8| 9| 9| 9| 9| 9|         U      O|
10MG   FS-2YR 12    12                      | 7| 8| 9| 0| 4| 5| 6| 6| 7| 3| 4| 5| 6| 7| 8| 0| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
URINARY SYSTEM

KIDNEY                                      |                                  +           +                            |  9       |
  LYMPHOMA MALIGNANT                        |                                  X           X                            |         5|
URETER                                      |                                                 +                         |  1       |
  LYMPHOMA MALIGNANT                        |                                                 X                         |         1|
URINARY BLADDER                             |                                              +                            |  8       |
  LYMPHOMA MALIGNANT                        |                                                                           |         3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   86
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:43.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|   S      M|
                                            | 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7|   U      O|
25MG   FS-2YR 13    13                      | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  M                                                                   |          |
GALLBLADDER                                 | +  +  +                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
INTESTINE LARGE                             | +  +  +                                                                   |          |
INTESTINE LARGE,CECUM                       | +  A  A                                                                   |          |
INTESTINE LARGE,COLON                       | +  A  +                                                                   |          |
INTESTINE LARGE,RECTUM                      | +  +  M                                                                   |          |
INTESTINE SMALL                             | +  A  A                                                                   |          |
INTESTINE SMALL,DUODENUM                    | +  A  A                                                                   |          |
INTESTINE SMALL,ILEUM                       | +  A  A                                                                   |          |
INTESTINE SMALL,JEJUNUM                     | +  A  A                                                                   |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HEPATOCELLULAR ADENOMA                    |                                                                           |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                       X                   |          |
  LYMPHOMA MALIGNANT                        | X                                               X     X                   |          |
MESENTERY                                   |                                                                           |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
PANCREAS                                    | +  +  A                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
SALIVARY GLANDS                             | +  +  +                                                                   |          |
STOMACH                                     | +  A  +                                                                   |          |
STOMACH,FORESTOMACH                         | +  A  +                                                                   |          |
STOMACH,GLANDULAR                           | +  A  +                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
TONGUE                                      | +  +  +                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +                                                                   |          |
BLOOD VESSEL,AORTA                          | +  +  +                                                                   |          |
HEART                                       | +  +  +                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   87
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:43.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|   S      M|
                                            | 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7|   U      O|
25MG   FS-2YR 13    13                      | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  M                                                                   |          |
ADRENAL GLAND,CORTEX                        | +  +  M                                                                   |          |
ADRENAL GLAND,MEDULLA                       | +  +  M                                                                   |          |
ISLETS, PANCREATIC                          | +  +  A                    +                                              |          |
  ADENOMA                                   |                            X                                              |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
PARATHYROID GLAND                           | M  M  M                                                                   |          |
PITUITARY GLAND                             | M  M  M                                                                   |          |
THYROID GLAND                               | +  +  M                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  M  M                                                                   |          |
OVARY                                       | +  +  M  +  +  +  +     +  +     +        +  +     +     +  +     +     + |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
UTERUS                                      | +  +  +     +     +  +           +     +  +     +  +     +     +  +  +    |          |
  FIBROSARCOMA                              |                      X                                                    |          |
VAGINA                                      | +  M  M                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  A  A                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
LYMPH NODE                                  | +  +  +              +                                +                   |          |
  FIBROSARCOMA,METASTATIC,UTERUS,RENAL      |                      X                                                    |          |
  LYMPHOMA MALIGNANT,INGUINAL               | X                                                                         |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
LYMPH NODE,MESENTERIC                       | +  +  M                                               +                   |          |
  LYMPHOMA MALIGNANT                        | X                                                     X                   |          |
SPLEEN                                      | +  +  +                    +                    +     +                   |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        | X                                               X     X                   |          |
THYMUS                                      | +  +  M                                         +                         |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   88
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:43.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|   S      M|
                                            | 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7|   U      O|
25MG   FS-2YR 13    13                      | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        | X                                               X                         |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  M                                                                   |          |
SKIN                                        | +  +  +                                                                   |          |
  FIBROSARCOMA                              |                                                                           |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +                                                                   |          |
BONE,FEMUR                                  | +  M  +                                                                   |          |
BONE,STERNUM                                | +  +  +                                                                   |          |
SKELETAL MUSCLE                             | +  +  +                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +                                                                   |          |
BRAIN,CEREBELLUM                            | +  +  +                                                                   |          |
BRAIN,CEREBRUM                              | +  +  +                                                                   |          |
PERIPHERAL NERVE                            | +  +  +                                                                   |          |
SPINAL CORD                                 | +  +  +                                                                   |          |
SPINAL CORD,THORACIC                        | +  +  +                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M                                                                   |          |
LUNG                                        | +  +  +                                                                   |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
NOSE                                        | +  +  +                                                                   |          |
TRACHEA                                     | +  +  M                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   89
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:43.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 1| 2| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 7| 5| 2| 6| 6| 6| 6| 6| 6| 6| 6| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 1| 1| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6|   S      M|
                                            | 0| 0| 0| 8| 8| 8| 9| 9| 9| 9| 9| 4| 4| 4| 4| 8| 8| 8| 8| 7| 7| 7| 7| 7| 7|   U      O|
25MG   FS-2YR 13    13                      | 8| 9| 7| 7| 8| 9| 0| 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 3| 4| 5| 6| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | A  A  A                                                                   |          |
HARDERIAN GLAND                             | +  +  +                                         +                         |          |
  ADENOMA                                   |                                                 X                         |          |
LACRIMAL GLAND                              | +  +  M                                                                   |          |
ZYMBAL'S GLAND                              | M  M  +                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +                                                                   |          |
  LYMPHOMA MALIGNANT                        | X                                                                         |          |
URINARY BLADDER                             | +  +  M                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   90
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:43.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   FS-2YR 13    13                      | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                                                           |  2       |
GALLBLADDER                                 |                                                                           |  3       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
INTESTINE LARGE                             |                                                                           |  3       |
INTESTINE LARGE,CECUM                       |                                                                           |  1       |
INTESTINE LARGE,COLON                       |                                                                           |  2       |
INTESTINE LARGE,RECTUM                      |                                                                           |  2       |
INTESTINE SMALL                             |                               +                                           |  2       |
INTESTINE SMALL,DUODENUM                    |                                                                           |  1       |
INTESTINE SMALL,ILEUM                       |                                                                           |  1       |
INTESTINE SMALL,JEJUNUM                     |                               +                                           |  2       |
  LYMPHOMA MALIGNANT                        |                               X                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA                    |                      X                                                    |         1|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                               X                                           |         4|
MESENTERY                                   |                   +                                                       |  1       |
  HEMANGIOSARCOMA                           |                   X                                                       |         1|
PANCREAS                                    |                                                                           |  2       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SALIVARY GLANDS                             |                                                                           |  3       |
STOMACH                                     |                                                                           |  2       |
STOMACH,FORESTOMACH                         |                                                                           |  2       |
STOMACH,GLANDULAR                           |                                                                           |  2       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TONGUE                                      |                                                                           |  3       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                                                           |  3       |
BLOOD VESSEL,AORTA                          |                                                                           |  3       |
HEART                                       |                                                                           |  3       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   91
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:44.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   FS-2YR 13    13                      | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                                                           |  2       |
ADRENAL GLAND,CORTEX                        |                                                                           |  2       |
ADRENAL GLAND,MEDULLA                       |                                                                           |  2       |
ISLETS, PANCREATIC                          |                                                                           |  3       |
  ADENOMA                                   |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PARATHYROID GLAND                           |                                                                           |  0       |
PITUITARY GLAND                             |                                                                           |  0       |
THYROID GLAND                               |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              |                                                                           |  1       |
OVARY                                       | +  +  +  +  +        +  +     +              +           +  +  +          | 28       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
UTERUS                                      | +  +  +        +     +        +  +     +        +  +  +  +  +             | 28       |
  FIBROSARCOMA                              |                                                                           |         1|
VAGINA                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                                                           |  1       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LYMPH NODE                                  |                +                                                          |  6       |
  FIBROSARCOMA,METASTATIC,UTERUS,RENAL      |                                                                           |         1|
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |         1|
  LYMPHOMA MALIGNANT,LUMBAR                 |                X                                                          |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                X                                                          |         1|
LYMPH NODE,MANDIBULAR                       |                +                                                          |  4       |
  LYMPHOMA MALIGNANT                        |                X                                                          |         2|
LYMPH NODE,MESENTERIC                       |                +                                                          |  4       |
  LYMPHOMA MALIGNANT                        |                X                                                          |         3|
SPLEEN                                      | +        +  +  +  +  +              +                          +  +       | 15       |
  HEMANGIOSARCOMA                           | X                 X                                                       |         2|
  LYMPHOMA MALIGNANT                        |                X                                                  X       |         5|
THYMUS                                      |                +                                                          |  4       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   92
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:44.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   FS-2YR 13    13                      | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |                X                                                          |         3|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                                                           |  2       |
SKIN                                        | +                 +                                            +          |  6       |
  FIBROSARCOMA                              |                                                                X          |         1|
  HEMANGIOSARCOMA                           | X                 X                                                       |         2|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                                                           |  3       |
BONE,FEMUR                                  |                                                                           |  2       |
BONE,STERNUM                                |                                                                           |  3       |
SKELETAL MUSCLE                             |                                                                           |  3       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                                                                           |  3       |
BRAIN,CEREBELLUM                            |                                                                           |  3       |
BRAIN,CEREBRUM                              |                                                                           |  3       |
PERIPHERAL NERVE                            |                                                                           |  3       |
SPINAL CORD                                 |                                                                           |  3       |
SPINAL CORD,THORACIC                        |                                                                           |  3       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                                                           |  2       |
LUNG                                        |          +                                                                |  4       |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |          X                                                                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        |                                                                           |  3       |
TRACHEA                                     |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   93
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:44.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 7| 0| 0| 0| 0| 0| 0| 0| 0| 6| 6| 6| 6| 7| 7| 7| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   FS-2YR 13    13                      | 9| 2| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         |                                                                           |  0       |
HARDERIAN GLAND                             |       +                                                                   |  5       |
  ADENOMA                                   |                                                                           |         1|
LACRIMAL GLAND                              |                                                                           |  2       |
ZYMBAL'S GLAND                              |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                                                                           |  3       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
URINARY BLADDER                             |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   94
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:50.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6|   S      M|
                                            | 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6|   U      O|
50MG   FS-2YR 14    14                      | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  +  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE LARGE,COLON                       | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | A  +  +  A  M  A  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,ILEUM                       | A  +  +  A  +  A  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                                   X       |          |
  LYMPHOMA MALIGNANT                        |                   X                 X        X                            |          |
PANCREAS                                    | A  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  M  M  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  M  +  +  + |          |
BLOOD VESSEL,AORTA                          | +  +  M  M  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  M  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                              X                            |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +  M  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   95
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:51.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6|   S      M|
                                            | 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6|   U      O|
50MG   FS-2YR 14    14                      | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | A  +  +  A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M |          |
PITUITARY GLAND                             | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  + |          |
  ADENOMA,PARS DISTALIS                     |                                                                      X    |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  M  +  +  M  +  +  M  M  +  M  M  +  +  +  +  +  +  +  +  + |          |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  + |          |
  CYSTADENOMA                               |                                                                           |          |
  GRANULOSA CELL TUMOR BENIGN               |                                                                           |          |
  HEMANGIOSARCOMA,PERIOVARIAN TISSUE        |             X                                                             |          |
  LUTEOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
  YOLK SAC CARCINOMA                        | X                                                                         |          |
UTERUS                                      | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
VAGINA                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
  FIBROSARCOMA                              |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                   X                                                       |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X                                                                      |          |
  LYMPHOMA MALIGNANT,RENAL                  |                   X                                                       |          |
  LYMPHOMA MALIGNANT,THORACIC               |                                              X                            |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |    X              X                 X        X                            |          |
LYMPH NODE,MESENTERIC                       | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |                   X                          X                            |          |
SPLEEN                                      | A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |    X                                X        X                            |          |
THYMUS                                      | M  +  +  M  +  +  M  +  +  +  +  +  +  M  +  M  +  +  +  +  +  M  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   96
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:51.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6|   S      M|
                                            | 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6|   U      O|
50MG   FS-2YR 14    14                      | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  + |          |
  ADENOCARCINOMA                            |                                                                           |          |
  ADENOMA                                   |                   X                                                       |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                X                                                          |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                   X     X  X                                              |          |
  HEMANGIOSARCOMA                           |             X                                                             |          |
  LYMPHOMA MALIGNANT                        |                   X                          X                            |          |
  YOLK SAC CARCINOMA,METASTATIC,OVARY       | X                                                                         |          |
NOSE                                        | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   97
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:51.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 5| 5| 6| 7| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 5| 0| 4| 4| 0| 5| 5| 5| 5| 5| 5| 5| 5| 3| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 8| 2| 4| 7| 0| 8| 6| 6| 6| 6| 6| 6| 6| 6| 6| 4| 5| 5| 5| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 1| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6|   S      M|
                                            | 3| 6| 6| 7| 7| 0| 2| 7| 8| 8| 8| 8| 8| 8| 8| 2| 4| 4| 4| 7| 7| 7| 7| 6| 6|   U      O|
50MG   FS-2YR 14    14                      | 9| 3| 4| 1| 0| 5| 3| 9| 0| 1| 2| 3| 4| 5| 6| 3| 3| 4| 5| 6| 7| 8| 9| 7| 8|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +  +  +  +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
URINARY BLADDER                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  M  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   98
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:57.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2|         U      O|
50MG   FS-2YR 14    14                      | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +       | 44       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,CECUM                       | +  +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |       X                                                                   |         1|
INTESTINE LARGE,COLON                       | +  +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE LARGE,RECTUM                      | +  +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 41       |
  LYMPHOMA MALIGNANT                        |                                                    X                      |         1|
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |                            X                       X                      |         2|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |             X                                                             |         2|
  LYMPHOMA MALIGNANT                        |    X  X              X  X                                   X     X       |         9|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |       X                                            X                      |         2|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |       X                                            X                      |         2|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +       | 46       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                    X                      |         2|
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +       | 44       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:   99
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:57.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2|         U      O|
50MG   FS-2YR 14    14                      | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
PITUITARY GLAND                             | +  +  +  +  +  +  M  +  +  +  +  M  +  M  +  M  +  +  +  +  +  +  +       | 42       |
  ADENOMA,PARS DISTALIS                     |                                                                           |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  M  +  +  M  M  +  +       | 37       |
OVARY                                       | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  CYSTADENOMA                               |                X                                                          |         1|
  GRANULOSA CELL TUMOR BENIGN               |                                                    X                      |         1|
  HEMANGIOSARCOMA,PERIOVARIAN TISSUE        |                                                                           |         1|
  LUTEOMA                                   |       X                                                                   |         1|
  LYMPHOMA MALIGNANT                        |    X                                                                      |         1|
  YOLK SAC CARCINOMA                        |                                                                           |         1|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  FIBROSARCOMA                              |                                                    X                      |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                      X                                                    |         2|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |    X                                                                      |         2|
  LYMPHOMA MALIGNANT,THORACIC               |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |       X                    X                       X                      |         7|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  M  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |    X  X                                            X              X       |         6|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |    X  X     X        X  X                 X        X  X  X  X     X       |        14|
THYMUS                                      | +  +  +  +  +  M  M  +  M  M  +  +  +  +  M  +  +  +  +  +  +  +  +       | 37       |
  LYMPHOMA MALIGNANT                        |       X                                            X                      |         2|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  100
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:57.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2|         U      O|
50MG   FS-2YR 14    14                      | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOCARCINOMA                            |                                     X                                     |         1|
  ADENOMA                                   |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROSARCOMA                              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROSARCOMA                              |          X                                                                |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |          X                    X                                           |         5|
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X                                            X                      |         4|
  YOLK SAC CARCINOMA,METASTATIC,OVARY       |                                                                           |         1|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  101
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:21:57.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|
                                            | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 6| 6| 6| 6| 7| 7| 7| 7| 8| 8| 8| 8| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 9|         S      M|
                                            | 6| 7| 7| 7| 9| 9| 9| 9| 0| 0| 5| 6| 6| 6| 6| 6| 6| 1| 1| 1| 2| 2| 2|         U      O|
50MG   FS-2YR 14    14                      | 9| 0| 1| 2| 6| 7| 8| 9| 0| 1| 9| 0| 1| 2| 3| 4| 5| 7| 8| 9| 0| 1| 2|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |                                              X                            |         1|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  M  +  +  +  +  +       | 43       |
  LYMPHOMA MALIGNANT                        |       X                                                                   |         1|
ZYMBAL'S GLAND                              | +  +  +  +  M  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |             X                                      X                      |         2|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |    X                                                                      |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  102
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:04.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
                                            | 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
                                            | 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|   S      M|
                                            | 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9|   U      O|
CONTRL FS-2YR 19    19                      | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
GALLBLADDER                                 | M  +  +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                     X             |          |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  A  +  + |          |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  A  +  + |          |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  A  +  + |          |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  A  +  + |          |
INTESTINE SMALL                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
INTESTINE SMALL,ILEUM                       | A  +  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
INTESTINE SMALL,JEJUNUM                     | A  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                                           |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |       X     X              X        X                       X             |          |
MESENTERY                                   |                                                             +             |          |
PANCREAS                                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
  LYMPHOMA MALIGNANT                        |       X     X              X                                              |          |
SALIVARY GLANDS                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                    X        X                                     |          |
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
TONGUE                                      | A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  103
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:04.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
                                            | 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
                                            | 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|   S      M|
                                            | 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9|   U      O|
CONTRL FS-2YR 19    19                      | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PARATHYROID GLAND                           | A  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
PITUITARY GLAND                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  + |          |
  ADENOMA,PARS DISTALIS                     |                                                                           |          |
  ADENOMA,PARS INTERMEDIA                   |          X                                                                |          |
THYROID GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
  ADENOMA,FOLLICULAR CELL                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | A  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  M  M  +  M  M  +  + |          |
OVARY                                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
  GRANULOSA CELL TUMOR BENIGN               |                                                                           |          |
  LUTEOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X     X                                                             |          |
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                            X                                              |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LEIOMYOMA                                 |                         X                                                 |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
VAGINA                                      | A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
  FIBROSARCOMA                              |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                     X     X                               |          |
LYMPH NODE                                  | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT,INGUINAL               |                                                                           |          |
  LYMPHOMA MALIGNANT,PANCREATIC             |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                             X     X                               |          |
LYMPH NODE,MESENTERIC                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  + |          |
  LYMPHOMA MALIGNANT                        |       X     X              X        X     X                               |          |
SPLEEN                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X     X              X        X  X  X                 X             |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  104
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:05.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
                                            | 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
                                            | 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|   S      M|
                                            | 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9|   U      O|
CONTRL FS-2YR 19    19                      | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | M  +  +  M  M  +  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  M  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                    X        X     X                 X             |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +  M  A  +  + |          |
  ADENOCARCINOMA                            |    X                                                                      |          |
SKIN                                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
  HEMANGIOMA                                |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
SKELETAL MUSCLE                             | A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  M  + |          |
LUNG                                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X                         |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA,MULTIPLE     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X     X              X        X                                     |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  105
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:05.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 2| 3| 6| 6|
                                            | 7| 2| 3| 7| 9| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 8| 5| 5|
                                            | 8| 6| 3| 3| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 3| 3| 3| 3| 7| 8| 6| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|   S      M|
                                            | 5| 7| 8| 8| 9| 1| 1| 4| 4| 4| 7| 7| 7| 7| 0| 0| 0| 4| 4| 4| 4| 6| 6| 9| 9|   U      O|
CONTRL FS-2YR 19    19                      | 7| 3| 1| 7| 5| 5| 6| 4| 5| 6| 3| 4| 5| 6| 4| 5| 6| 5| 6| 7| 8| 6| 9| 3| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  + |          |
HARDERIAN GLAND                             | A  +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  M  +  + |          |
  ADENOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
LACRIMAL GLAND                              | A  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  M  +  + |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
ZYMBAL'S GLAND                              | A  +  M  M  +  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                             X     X                               |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  A  +  + |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |       X                    X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  106
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:11.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7|         S      M|
                                            | 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5|         U      O|
CONTRL FS-2YR 19    19                      | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +       | 45       |
GALLBLADDER                                 | A  +  +  +  +  +  M  +  M  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 41       |
  LYMPHOMA MALIGNANT                        |                X                                                          |         3|
INTESTINE LARGE                             | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,CECUM                       | +  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE LARGE,COLON                       | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE LARGE,RECTUM                      | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
INTESTINE SMALL                             | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE SMALL,DUODENUM                    | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
INTESTINE SMALL,ILEUM                       | A  A  A  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 40       |
INTESTINE SMALL,JEJUNUM                     | A  A  A  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +       | 41       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                   X                                                       |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                X              X              X                    X       |         9|
MESENTERY                                   |                                                                           |  1       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                X                             X                            |         5|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                               X              X                            |         5|
STOMACH                                     | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
STOMACH,FORESTOMACH                         | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
STOMACH,GLANDULAR                           | +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  M  +  M  +  M  +  +  +  +  +  +  +  +       | 41       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  M  +  M  +  M  +  +  +  +  +  +  +  +       | 41       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  107
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:11.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7|         S      M|
                                            | 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5|         U      O|
CONTRL FS-2YR 19    19                      | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +       | 44       |
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  ADENOMA,PARS DISTALIS                     |                                  X                                        |         1|
  ADENOMA,PARS INTERMEDIA                   |                                                                           |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  ADENOMA,FOLLICULAR CELL                   |                                        X                                  |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  M  +  +  +  +  +  +  +       | 38       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  GRANULOSA CELL TUMOR BENIGN               |          X                                                                |         1|
  LUTEOMA                                   |                            X                                              |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
  LYMPHOMA MALIGNANT,PERIOVARIAN TISSUE     |                                              X                            |         2|
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LEIOMYOMA                                 |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  FIBROSARCOMA                              |                                                                   X       |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                               X                                   X       |         4|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT,INGUINAL               |                                              X                            |         1|
  LYMPHOMA MALIGNANT,PANCREATIC             |                                              X                            |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                X  X           X              X                            |         7|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                X              X              X                            |         8|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                               X              X           X        X       |        11|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  108
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:11.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7|         S      M|
                                            | 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5|         U      O|
CONTRL FS-2YR 19    19                      | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

THYMUS                                      | M  M  M  +  +  +  M  +  +  +  M  +  +  +  +  +  +  +  +  M  +  +  +       | 36       |
  LYMPHOMA MALIGNANT                        |                X                             X                 X          |         8|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  ADENOCARCINOMA                            |                                                                           |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  HEMANGIOMA                                |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
SKELETAL MUSCLE                             | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                              X                            |         2|
  ALVEOLAR/BRONCHIOLAR ADENOMA,MULTIPLE     |                   X                                                       |         1|
  LYMPHOMA MALIGNANT                        |                X                                                  X       |         6|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  109
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:11.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 5| 5| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 7| 7| 0| 2| 2| 2| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7|         S      M|
                                            | 9| 9| 2| 3| 3| 4| 0| 0| 0| 3| 3| 4| 5| 5| 5| 5| 9| 9| 9| 9| 5| 5| 5|         U      O|
CONTRL FS-2YR 19    19                      | 5| 6| 7| 8| 9| 0| 6| 7| 8| 8| 9| 0| 5| 6| 7| 8| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | A  A  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 42       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
  ADENOMA                                   |       X                                                                   |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
LACRIMAL GLAND                              | M  +  +  +  +  +  +  +  +  +  +  M  M  M  +  +  +  +  +  +  +  M  M       | 37       |
  LYMPHOMA MALIGNANT                        |                                              X                            |         2|
ZYMBAL'S GLAND                              | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +       | 41       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                X              X              X                            |         6|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                              X                            |         3|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  110
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:13.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
                                            | 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
                                            | 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0|   U      O|
10MG   FS-2YR 20    20                      | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | A                                                           +  M  +  M  + |          |
GALLBLADDER                                 | A                                                           +  +  M  +  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
INTESTINE LARGE                             | A                                                           A  +  A  +  + |          |
INTESTINE LARGE,CECUM                       | M                                                           A  +  A  A  + |          |
INTESTINE LARGE,COLON                       | M                                                           A  +  A  +  + |          |
INTESTINE LARGE,RECTUM                      | A                                                           A  +  A  +  + |          |
INTESTINE SMALL                             | M                                                           A  +  A  +  + |          |
INTESTINE SMALL,DUODENUM                    | M                                                           A  +  A  A  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,ILEUM                       | M                                                           A  +  A  A  + |          |
INTESTINE SMALL,JEJUNUM                     | M                                                           A  +  A  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                        X                                  |          |
  HEPATOCELLULAR CARCINOMA                  |                                           X                             X |          |
  HEPATOCHOLANGIOCARCINOMA                  |                                                                         X |          |
  HISTIOCYTIC SARCOMA                       |                                                                   X  X    |          |
  LYMPHOMA MALIGNANT                        |                                                    X                      |          |
PANCREAS                                    | A                                                           A  +  A  +  A |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
SALIVARY GLANDS                             | A                                                           +  +  +  +  + |          |
STOMACH                                     | M                                                           A  +  A  +  + |          |
STOMACH,FORESTOMACH                         | M                                                           A  +  A  +  + |          |
STOMACH,GLANDULAR                           | M                                                           A  +  A  +  + |          |
TONGUE                                      | +                                                           +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                                                           M  M  +  M  + |          |
BLOOD VESSEL,AORTA                          | +                                                           M  M  +  M  + |          |
HEART                                       | +                                                           +  +  +  +  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  111
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:14.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
                                            | 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
                                            | 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0|   U      O|
10MG   FS-2YR 20    20                      | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A                                                           A  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | A                                                           A  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | A                                                           A  +  M  +  + |          |
  PHEOCHROMOCYTOMA BENIGN                   |                                                                           |          |
ISLETS, PANCREATIC                          | A                                                           A  +  A  +  A |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
PARATHYROID GLAND                           | A                                                           +  M  +  M  M |          |
PITUITARY GLAND                             | A                                                           M  M  +  M  + |          |
THYROID GLAND                               | A                                                           +  M  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +                                                           +  +  +  +  + |          |
OVARY                                       | A     +  +     +  +  +           +        +  +              +  +  +  +  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  HISTIOCYTIC SARCOMA                       |                                                                   X  X    |          |
UTERUS                                      | A     +     +  +  +  +     +  +  +     +     +     +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                               X                                           |          |
  HISTIOCYTIC SARCOMA                       |                                                                   X  X    |          |
VAGINA                                      | A                                                           +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                   X  X    |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                                                           +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
LYMPH NODE                                  | +                                                           +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                           |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
  LYMPHOMA MALIGNANT,THORACIC               |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | A                                                           +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE,MESENTERIC                       | +                                                           A  +  A  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  112
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:14.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
                                            | 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
                                            | 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0|   U      O|
10MG   FS-2YR 20    20                      | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        | X                                                                         |          |
SPLEEN                                      | M        +           +     +                       +        +  +  A  +  + |          |
  HISTIOCYTIC SARCOMA                       |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |          X                                         X                      |          |
THYMUS                                      | A                                                           +  +  M  M  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | A                             +                             +  +  +  +  M |          |
  ADENOCARCINOMA                            |                                                             X             |          |
SKIN                                        | A                                                           +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                                                           +  +  +  +  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER,|                                                                         X |          |
      MANDIBLE                              |                                                                           |          |
BONE,FEMUR                                  | +                                                           +  +  +  +  + |          |
BONE,STERNUM                                | +                                                           +  +  +  +  + |          |
SKELETAL MUSCLE                             | +                                                           +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                                                           +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +                                                           +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +                                                           +  +  +  +  + |          |
PERIPHERAL NERVE                            | +                                                           +  +  +  +  + |          |
SPINAL CORD                                 | +                                                           +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +                                                           +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | A                                                           +  M  M  M  + |          |
LUNG                                        | A                                      +                    +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                        X                                  |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  113
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:14.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 5| 5| 6| 6|
                                            | 0| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0| 3| 9| 0| 6|
                                            | 4| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 7| 3| 2| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 6| 2| 2| 2| 2| 5| 5| 5| 8| 8| 8| 8| 0| 1| 1| 1| 5| 5| 5| 5| 7| 7| 8| 8| 0|   U      O|
10MG   FS-2YR 20    20                      | 8| 0| 1| 2| 3| 1| 2| 3| 0| 1| 2| 3| 9| 0| 1| 2| 2| 3| 4| 5| 2| 4| 4| 5| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
NOSE                                        | +                                                           +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
TRACHEA                                     | A                                                           +  M  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | A                                                           A  +  A  A  A |          |
HARDERIAN GLAND                             | +                                                           +  +  +  +  M |          |
LACRIMAL GLAND                              | A                                                           +  +  +  M  + |          |
ZYMBAL'S GLAND                              | +                                                           +  +  M  +  M |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A                                                           +  +  +  +  + |          |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                         X |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
URINARY BLADDER                             | A                                                           A  +  A  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  114
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:15.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6|         U      O|
10MG   FS-2YR 20    20                      | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +                    +                                                    |  5       |
GALLBLADDER                                 | +                    +                                                    |  6       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
INTESTINE LARGE                             | +                    +                                                    |  5       |
INTESTINE LARGE,CECUM                       | +                    +                                                    |  4       |
INTESTINE LARGE,COLON                       | +                    +                                                    |  5       |
INTESTINE LARGE,RECTUM                      | +                    +                                                    |  5       |
INTESTINE SMALL                             | +                    +                                      +     +       |  7       |
INTESTINE SMALL,DUODENUM                    | +                    +                                      +             |  5       |
  LYMPHOMA MALIGNANT                        |                                                             X             |         1|
INTESTINE SMALL,ILEUM                       | +                    +                                                    |  4       |
INTESTINE SMALL,JEJUNUM                     | +                    +                                      +     +       |  7       |
  LYMPHOMA MALIGNANT                        |                                                             X     X       |         2|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         2|
  HEPATOCHOLANGIOCARCINOMA                  |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        |       X                 X                                X                |         4|
PANCREAS                                    | +                    +                                +                   |  5       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
SALIVARY GLANDS                             | +                    +                                                    |  7       |
STOMACH                                     | +                    +                                                    |  5       |
STOMACH,FORESTOMACH                         | +                    +                                                    |  5       |
STOMACH,GLANDULAR                           | +                    +                                                    |  5       |
TONGUE                                      | +                    +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +                    +                                                    |  5       |
BLOOD VESSEL,AORTA                          | +                    +                                                    |  5       |
HEART                                       | +                    +                                                    |  8       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  115
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:15.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6|         U      O|
10MG   FS-2YR 20    20                      | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +                    +                                +                   |  7       |
ADRENAL GLAND,CORTEX                        | +                    +                                                    |  6       |
ADRENAL GLAND,MEDULLA                       | +                    +                                +                   |  6       |
  PHEOCHROMOCYTOMA BENIGN                   |                                                       X                   |         1|
ISLETS, PANCREATIC                          | +                    +                                                    |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
PARATHYROID GLAND                           | +                    M                                                    |  3       |
PITUITARY GLAND                             | +                    +                                                    |  4       |
THYROID GLAND                               | +                    +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +                    M                                                    |  7       |
OVARY                                       | +  +                 +  +        +  +  +              +        +          | 22       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
UTERUS                                      | +  +        +     +  +        +           +        +     +  +  +  +       | 30       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
VAGINA                                      | +                    +                                                    |  7       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +                    +                                                    |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
LYMPH NODE                                  | +     +              +  +              +                 +  +             | 13       |
  LYMPHOMA MALIGNANT                        |                                        X                                  |         1|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |       X                 X                                                 |         2|
  LYMPHOMA MALIGNANT,RENAL                  |       X                                                                   |         1|
  LYMPHOMA MALIGNANT,THORACIC               |                                                          X                |         1|
LYMPH NODE,MANDIBULAR                       | +     +              +                                                    |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X                                                                   |         1|
LYMPH NODE,MESENTERIC                       | +     +              +  +                                +  +             | 10       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  116
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:15.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6|         U      O|
10MG   FS-2YR 20    20                      | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |       X                 X                                X  X             |         5|
SPLEEN                                      | +     +              +  +  +        +              +     +  +     +       | 18       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |       X                 X           X                    X  X     X       |         8|
THYMUS                                      | +                    M                                                    |  4       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +                    M                                                    |  6       |
  ADENOCARCINOMA                            |                                                                           |         1|
SKIN                                        | +                    +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +                    +                                                    |  8       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER,|                                                                           |         1|
      MANDIBLE                              |                                                                           |          |
BONE,FEMUR                                  | +                    +                                                    |  8       |
BONE,STERNUM                                | +                    +                                                    |  8       |
SKELETAL MUSCLE                             | +                    +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +                    +                                                    |  8       |
BRAIN,CEREBELLUM                            | +                    +                                                    |  8       |
BRAIN,CEREBRUM                              | +                    +                                                    |  8       |
PERIPHERAL NERVE                            | +                    +                                                    |  8       |
SPINAL CORD                                 | +                    +                                                    |  8       |
SPINAL CORD,THORACIC                        | +                    +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +                    +                                                    |  4       |
LUNG                                        | +                    +                                                    |  8       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              | X                                                                         |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  117
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:15.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 6| 2| 2| 2| 2| 3| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 3| 5| 6| 6| 8| 9| 0| 0| 0| 3| 5| 5| 5| 8| 8| 8| 6| 6| 6| 6|         U      O|
10MG   FS-2YR 20    20                      | 1| 2| 3| 4| 9| 0| 1| 4| 9| 0| 1| 2| 5| 0| 1| 2| 4| 5| 6| 2| 3| 4| 5|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
NOSE                                        | +                    +                                                    |  8       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
TRACHEA                                     | +                    M                                                    |  4       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +                    +                                                    |  3       |
HARDERIAN GLAND                             | +                    +                                                    |  7       |
LACRIMAL GLAND                              | +                    +                                                    |  6       |
ZYMBAL'S GLAND                              | +                    +                                                    |  6       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +     +              +                                                    |  8       |
  HEPATOCHOLANGIOCARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
URINARY BLADDER                             | +                    +                                                    |  5       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  118
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:18.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
                                            | 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
                                            | 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1|   U      O|
25MG   FS-2YR 21    21                      | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +                                                     +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +                                                     +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +                                                     +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | +  +  +                                                     +  +  +  A  + |          |
INTESTINE LARGE,COLON                       | +  +  +                                                     +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | +  +  +                                                     +  +  +  +  + |          |
INTESTINE SMALL                             | +  +  +                                                     +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | +  +  +                                                     +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  +  +                                                     +  +  +  A  + |          |
INTESTINE SMALL,JEJUNUM                     | +  +  +                                                     +  +  +  A  + |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |       X                                                                   |          |
  HEPATOCELLULAR ADENOMA                    |       X  X                                                                |          |
  HEPATOCELLULAR CARCINOMA                  |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  ITO CELL TUMOR NOS                        |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                            X                                            X |          |
PANCREAS                                    | +  +  +                                                     +  +  +  +  + |          |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|       X                                                                   |          |
      E                                     |                                                                           |          |
SALIVARY GLANDS                             | +  +  +                                                     +  +  +  +  + |          |
STOMACH                                     | +  +  +                                                     +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +                                                     +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +                                                     +  +  +  +  + |          |
TONGUE                                      | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +                                                     +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  M  +                                                     +  +  +  +  + |          |
HEART                                       | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +                                                     +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +                                                     +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  119
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:18.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
                                            | 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
                                            | 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1|   U      O|
25MG   FS-2YR 21    21                      | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          | +  +  +                                                     +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
PARATHYROID GLAND                           | +  M  +                                                     M  +  +  M  M |          |
PITUITARY GLAND                             | +  +  +                                   +                 +  +  M  +  M |          |
  ADENOMA,PARS DISTALIS                     |                                           X                               |          |
THYROID GLAND                               | +  +  +                                                     +  +  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  M  +                                                     M  +  +  +  + |          |
OVARY                                       | +  +  +  +  +        +     +  +  +     +           +  +     +  +  +  M  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
UTERUS                                      | +  +  +  +  +  +     +  +  +                 +     +     +  +  +  +  +  + |          |
  FIBROMA                                   |                                                                           |          |
  HEMANGIOSARCOMA                           |    X                                                                      |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
VAGINA                                      | +  +  +                                                     +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +                                                     +  +  +  +  + |          |
LYMPH NODE                                  | +  +  +                 +                                   +  +  +  A  + |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                         X                                                 |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +                                                     +  +  +  A  + |          |
  SQUAMOUS CELL CARCINOMA,METASTATIC,NOSE   |                                                                   X       |          |
LYMPH NODE,MESENTERIC                       | +  +  +                                                     M  +  +  A  + |          |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|       X                                                                   |          |
      E                                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                X          |          |
SPLEEN                                      | +  +  +                    +                 +              +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |    X                                                                      |          |
  LYMPHOMA MALIGNANT                        |                            X                                              |          |
THYMUS                                      | M  M  +  +              +                                   +  +  M  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  120
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:18.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
                                            | 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
                                            | 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1|   U      O|
25MG   FS-2YR 21    21                      | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |                         X                                      X        X |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +           +                                         +  +  +  +  + |          |
  ADENOCARCINOMA                            |                   X                                                       |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
SKIN                                        | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +                                                     +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +                                                     +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +                                                     +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +                                                     +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +                                                     +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +                                                     +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +                                                     +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +                                                     +  +  +  M  + |          |
SPINAL CORD,THORACIC                        | +  +  +                                                     +  +  +  M  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M                                                     +  +  +  +  + |          |
LUNG                                        | +  +  +                 +                                   +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,MULTIPLE   |                         X                                                 |          |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|       X                                                                   |          |
      E                                     |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |       X                                                                   |          |
  HISTIOCYTIC SARCOMA                       |                                                                      X    |          |
NOSE                                        | +  +  +                                                     +  +  +  +  + |          |
  SQUAMOUS CELL CARCINOMA                   |                                                                   X       |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  121
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:18.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 4| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 6| 6| 6| 7|
                                            | 3| 6| 7| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 6| 5| 8| 0|
                                            | 9| 0| 7| 2| 2| 2| 2| 2| 2| 2| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 8| 3| 4| 5| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 5| 8| 9| 1| 1| 1| 4| 4| 4| 4| 7| 7| 0| 0| 0| 0| 4| 4| 4| 4| 8| 0| 0| 1| 1|   U      O|
25MG   FS-2YR 21    21                      | 6| 4| 1| 2| 3| 4| 0| 1| 2| 3| 1| 2| 0| 1| 2| 3| 1| 2| 3| 4| 1| 6| 9| 5| 9|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

TRACHEA                                     | +  +  +                                                     +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  A  A                                                     +  +  +  A  A |          |
HARDERIAN GLAND                             | +  +  +                                                     +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
LACRIMAL GLAND                              | +  M  +                                                     +  +  M  +  + |          |
ZYMBAL'S GLAND                              | M  +  +                                                     +  +  M  +  + |          |
  SQUAMOUS CELL CARCINOMA                   |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +                                                     +  +  +  +  + |          |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|       X                                                                   |          |
      E                                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
URINARY BLADDER                             | +  +  +                                                     +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  122
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:19.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5|         U      O|
25MG   FS-2YR 21    21                      | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                      +                                      +             | 10       |
GALLBLADDER                                 |                      +                                      M             |  9       |
INTESTINE LARGE                             |                      +                                      A             |  9       |
INTESTINE LARGE,CECUM                       |                      +                                      A             |  8       |
INTESTINE LARGE,COLON                       |                      +                                      A             |  9       |
INTESTINE LARGE,RECTUM                      |                      +                                      A             |  9       |
INTESTINE SMALL                             |                      +        +                             A             | 10       |
INTESTINE SMALL,DUODENUM                    |                      +        +                             A             |  9       |
INTESTINE SMALL,ILEUM                       |                      M                                      A             |  7       |
INTESTINE SMALL,JEJUNUM                     |                      +                                      A             |  8       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA                    |                                                                           |         2|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                      X                                      X             |         2|
  ITO CELL TUMOR NOS                        |                                                 X                         |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         3|
PANCREAS                                    |                      +                                      +             | 10       |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|                                                                           |         1|
      E                                     |                                                                           |          |
SALIVARY GLANDS                             |                      +                                      +             | 10       |
STOMACH                                     |                      +                                      A             |  9       |
STOMACH,FORESTOMACH                         |                      +                                      A             |  9       |
STOMACH,GLANDULAR                           |                      +                                      A             |  9       |
TONGUE                                      |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                      +                                      +             |  8       |
BLOOD VESSEL,AORTA                          |                      +                                      +             |  8       |
HEART                                       |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                      +                                      +             | 10       |
ADRENAL GLAND,CORTEX                        |                      +                                      +             | 10       |
ADRENAL GLAND,MEDULLA                       |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  123
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:19.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5|         U      O|
25MG   FS-2YR 21    21                      | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ISLETS, PANCREATIC                          |                      +        +                             +             | 11       |
  ADENOMA                                   |                               X                                           |         1|
PARATHYROID GLAND                           |                      +                                      M             |  5       |
PITUITARY GLAND                             |                      +                                      +             |  9       |
  ADENOMA,PARS DISTALIS                     |                                                                           |         1|
THYROID GLAND                               |                      +                                      +             |  9       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              |                      +                                      +             |  8       |
OVARY                                       | +  +        +  +  +  +        +        +  +     +  +     +  +  +          | 30       |
  HISTIOCYTIC SARCOMA                       |                      X                                      X             |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
UTERUS                                      | +  +     +  +     +  +  +  +  +     +     +  +  +  +  +  +  +     +       | 35       |
  FIBROMA                                   |    X                                                                      |         1|
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                      X  X                                   X             |         3|
VAGINA                                      |                      +                                      +             | 10       |
  HISTIOCYTIC SARCOMA                       |                      X                                      X             |         3|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                      +                                      +             | 10       |
LYMPH NODE                                  |                      +              +                       +             | 11       |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                     X                                     |         1|
LYMPH NODE,MANDIBULAR                       |                      +                                      +             |  9       |
  SQUAMOUS CELL CARCINOMA,METASTATIC,NOSE   |                                                                           |         1|
LYMPH NODE,MESENTERIC                       |                      +                                      +             |  8       |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|                                                                           |         1|
      E                                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SPLEEN                                      |                +     +              +     +  +        +     +             | 17       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                     X                                     |         2|
THYMUS                                      |                      M                                      +             |  7       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  124
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:19.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5|         U      O|
25MG   FS-2YR 21    21                      | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |         3|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                      +                 +                    M             | 11       |
  ADENOCARCINOMA                            |                                        X                                  |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
SKIN                                        |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                      +                                      +             | 10       |
BONE,FEMUR                                  |                      +                                      +             | 10       |
BONE,STERNUM                                |                      +                                      +             | 10       |
SKELETAL MUSCLE                             |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                      +                                      +             | 10       |
BRAIN,CEREBELLUM                            |                      +                                      +             | 10       |
BRAIN,CEREBRUM                              |                      +                                      +             | 10       |
PERIPHERAL NERVE                            |                      +                                      +             | 10       |
SPINAL CORD                                 |                      +                                      +             |  9       |
SPINAL CORD,THORACIC                        |                      +                                      +             |  9       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                      +                                      +             |  9       |
LUNG                                        |                      +                                      +             | 11       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                             X             |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA,MULTIPLE   |                                                                           |         1|
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|                                                                           |         1|
      E                                     |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                             X             |         2|
NOSE                                        |                      +                                      +             | 10       |
  SQUAMOUS CELL CARCINOMA                   |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  125
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:19.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 4| 2| 2| 2| 3| 3| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 3| 3| 3| 6| 6| 6| 6| 8| 0| 0| 0| 3| 3| 5| 5| 8| 8| 8| 9| 5| 5| 5| 5|         U      O|
25MG   FS-2YR 21    21                      | 5| 6| 7| 2| 3| 4| 5| 6| 3| 4| 5| 6| 7| 3| 4| 7| 8| 9| 0| 1| 2| 3| 4|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

TRACHEA                                     |                      +                                      +             | 10       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                      A     +                                A             |  5       |
HARDERIAN GLAND                             |                      +                                      +             | 10       |
  HISTIOCYTIC SARCOMA                       |                      X                                                    |         1|
LACRIMAL GLAND                              |                      M                                      +             |  7       |
ZYMBAL'S GLAND                              |                      +                                      +             |  8       |
  SQUAMOUS CELL CARCINOMA                   |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                      +                                      +             | 10       |
  CARCINOMA,METASTATIC,UNCERTAIN PRIMARY SIT|                                                                           |         1|
      E                                     |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
URINARY BLADDER                             |                      +                                      +             | 10       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  126
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:26.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
                                            | 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
                                            | 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3|   S      M|
                                            | 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4|   U      O|
50MG   FS-2YR 22    22                      | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,COLON                       | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,ILEUM                       | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,JEJUNUM                     | A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |                                                                           |          |
  HEPATOCELLULAR CARCINOMA                  |                                     X                                     |          |
  LYMPHOMA MALIGNANT                        |          X                                      X                         |          |
MESENTERY                                   |             +                                                             |          |
PANCREAS                                    | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH                                     | +  +  +  A  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  A  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,GLANDULAR                           | +  +  +  A  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ISLETS, PANCREATIC                          | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  127
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:26.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
                                            | 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
                                            | 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3|   S      M|
                                            | 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4|   U      O|
50MG   FS-2YR 22    22                      | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PARATHYROID GLAND                           | M  +  +  A  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  + |          |
PITUITARY GLAND                             | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  M |          |
  ADENOMA,PARS DISTALIS                     |                                     X                                     |          |
  CARCINOMA,PARS DISTALIS                   |                                                                   X       |          |
THYROID GLAND                               | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  M  +  +  +  M  +  +  +  +  +  +  +  +  M  M  +  M  M  +  M  + |          |
OVARY                                       | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                                X          |          |
  POLYP                                     |                                     X                                     |          |
VAGINA                                      | +  M  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA                              |                                                                           |          |
  POLYP                                     |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,METASTATIC,| X                                                                         |          |
      LUNG,MEDIASTINAL                      |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |                                                                           |          |
  LYMPHOMA MALIGNANT,MEDIASTINAL            |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LYMPH NODE,MESENTERIC                       | M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SPLEEN                                      | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |       X                                                                   |          |
  LYMPHOMA MALIGNANT                        |                                                 X                         |          |
THYMUS                                      | M  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  M  M  M  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  128
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:26.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
                                            | 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
                                            | 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3|   S      M|
                                            | 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4|   U      O|
50MG   FS-2YR 22    22                      | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOCARCINOMA                            |                                  X                                        |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  OSTEOSARCOMA,PELVIS                       |    X                                                                      |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,METASTATIC,| X                                                                         |          |
      LUNG,ADVENTITIA                       |                                                                           |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,METASTATIC,PITUITARY GLAND      |                                                                   X       |          |
PERIPHERAL NERVE                            | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                      X                                                    |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            | X        X                                                                |          |
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
  OSTEOSARCOMA,METASTATIC,BONE              |    X                                                                      |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  129
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:26.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 3| 4| 6| 7| 7|
                                            | 1| 7| 7| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 3| 4| 4| 4| 4| 4| 8| 8| 9| 4| 4|
                                            | 7| 5| 6| 5| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 7| 4| 4| 3| 3| 3| 1| 4| 7| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3|   S      M|
                                            | 7| 8| 9| 0| 1| 1| 1| 4| 4| 4| 5| 7| 7| 7| 9| 0| 0| 4| 5| 5| 6| 7| 2| 4| 4|   U      O|
50MG   FS-2YR 22    22                      | 2| 9| 0| 3| 7| 8| 9| 7| 8| 9| 0| 7| 8| 9| 9| 7| 8| 9| 0| 1| 8| 1| 0| 1| 2|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  A  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                           X                               |          |
  CARCINOMA                                 |                                                                           |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |          X                                                                |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  130
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:32.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6|         U      O|
50MG   FS-2YR 22    22                      | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +       | 44       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                               X                                           |         1|
  HEPATOCELLULAR CARCINOMA                  |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |    X     X     X              X                                           |         6|
MESENTERY                                   |                                                                           |  1       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 47       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  131
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:32.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6|         U      O|
50MG   FS-2YR 22    22                      | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

PARATHYROID GLAND                           | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 43       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +       | 43       |
  ADENOMA,PARS DISTALIS                     |                                                                           |         1|
  CARCINOMA,PARS DISTALIS                   |                                                                           |         1|
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  +  +  +  +  M  +  +  +  +  +  M  +  +  M  M  M  M  +  +  +       | 35       |
OVARY                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
UTERUS                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |             X                                                             |         2|
  POLYP                                     |                                                                           |         1|
VAGINA                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  FIBROSARCOMA                              |                                                 X                         |         1|
  POLYP                                     |                                           X                               |         1|
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,METASTATIC,|                                                                           |         1|
      LUNG,MEDIASTINAL                      |                                                                           |          |
  LYMPHOMA MALIGNANT,LUMBAR                 |          X                                                                |         1|
  LYMPHOMA MALIGNANT,MEDIASTINAL            |          X                                                                |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                 X                         |         2|
  LYMPHOMA MALIGNANT                        |    X     X     X                       X                                  |         5|
THYMUS                                      | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 40       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  132
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:32.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6|         U      O|
50MG   FS-2YR 22    22                      | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  M  +  +  +  +  +  +       | 46       |
  ADENOCARCINOMA                            |          X           X              X                             X       |         5|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA,METASTATIC,SPLEEN         |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  OSTEOSARCOMA,PELVIS                       |                                                                           |         1|
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,METASTATIC,|                                                                           |         1|
      LUNG,ADVENTITIA                       |                                                                           |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CARCINOMA,METASTATIC,PITUITARY GLAND      |                                                                           |         1|
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                                           |         1|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |         2|
  CARCINOMA,METASTATIC,HARDERIAN GLAND      |                   X                                                       |         1|
  LYMPHOMA MALIGNANT                        |                X                                                          |         1|
  OSTEOSARCOMA,METASTATIC,BONE              |                                                                           |         1|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  M  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  133
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:32.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
FEMALE                      CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 7| 7| 7| 7|         S      M|
                                            | 4| 4| 6| 6| 6| 0| 1| 1| 1| 4| 4| 5| 6| 6| 6| 9| 9| 9| 9| 5| 5| 6| 6|         U      O|
50MG   FS-2YR 22    22                      | 3| 4| 6| 7| 8| 9| 0| 1| 2| 1| 2| 9| 0| 1| 2| 5| 6| 7| 8| 8| 9| 0| 1|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   | X                                                     X                   |         3|
  CARCINOMA                                 |                   X                                                       |         1|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +       | 46       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                               X                                           |         2|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  134
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:39.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
                                            | 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2|   U      O|
CONTRL MS-2YR 27    27                      | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                       X                   |          |
  HEPATOBLASTOMA                            |                                                                           |          |
  HEPATOCELLULAR ADENOMA                    |             X  X                       X        X     X                 X |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                              X                            |          |
  HEPATOCELLULAR CARCINOMA                  |    X     X                                   X                 X          |          |
  HEPATOCELLULAR CARCINOMA,MULTIPLE         |                                                                           |          |
  HEPATOCHOLANGIOCARCINOMA                  |                                                                   X       |          |
  HISTIOCYTIC SARCOMA                       |                                                             X           X |          |
  LYMPHOMA MALIGNANT                        | X                                                  X                      |          |
MESENTERY                                   |                +                                                          |          |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  135
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:39.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
                                            | 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2|   U      O|
CONTRL MS-2YR 27    27                      | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
PARATHYROID GLAND                           | +  +  +  M  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  M  +  M |          |
PITUITARY GLAND                             | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  I  M  +  +  M |          |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |       X                                                              X    |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  + |          |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                       X                   |          |
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA,LUMBAR                |                                                                         X |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                         X |          |
  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                                                X          |          |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  HEMANGIOSARCOMA                           |                                                       X                   |          |
  LYMPHOMA MALIGNANT                        | X                                                  X                      |          |
THYMUS                                      | M  M  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  +  +  M  M  +  A |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  136
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:39.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
                                            | 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2|   U      O|
CONTRL MS-2YR 27    27                      | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  +  M  M  M  M  M  M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M  M |          |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
  FIBROSARCOMA                              |                                                                           |          |
  HEMANGIOSARCOMA                           |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                     X              X           X          |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                              X        X     X             |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  137
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:40.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 0| 2| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 0|
                                            | 6| 0| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 8|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 1| 2| 2| 3| 3| 5| 5| 6| 6| 8| 8| 9| 9| 1| 1| 1| 2| 3| 5| 5| 5| 5| 6| 2|   U      O|
CONTRL MS-2YR 27    27                      | 0| 0| 8| 9| 0| 1| 8| 9| 0| 1| 8| 9| 0| 1| 7| 8| 9| 0| 3| 6| 7| 8| 9| 0| 6|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                   X                                                       |          |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  M  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                                                         X |          |
  LYMPHOMA MALIGNANT                        |                                                    X                      |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  138
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:46.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1|         U      O|
CONTRL MS-2YR 27    27                      | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                             X             |         1|
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOBLASTOMA                            |    X                                                                      |         1|
  HEPATOCELLULAR ADENOMA                    |          X  X     X  X  X  X        X           X              X  X       |        16|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                          X                |         2|
  HEPATOCELLULAR CARCINOMA                  |    X     X     X                                         X     X          |         9|
  HEPATOCELLULAR CARCINOMA,MULTIPLE         |                                  X                                        |         1|
  HEPATOCHOLANGIOCARCINOMA                  |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         2|
  LYMPHOMA MALIGNANT                        | X                                                           X             |         4|
MESENTERY                                   |                                                                           |  1       |
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BLOOD VESSEL,AORTA                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  139
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:46.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1|         U      O|
CONTRL MS-2YR 27    27                      | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PARATHYROID GLAND                           | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 43       |
PITUITARY GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 44       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        | X                                                                         |         1|
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA,LUMBAR                |                                                                           |         1|
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |         1|
  LYMPHOMA MALIGNANT,RENAL                  |                                                             X             |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X                                                                         |         2|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        | X                                                           X             |         2|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +       | 46       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  LYMPHOMA MALIGNANT                        | X                                                           X             |         4|
THYMUS                                      | +  +  +  +  +  +  +  +  +  +  +  M  +  M  M  +  +  M  +  M  +  +  +       | 36       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  140
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:46.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1|         U      O|
CONTRL MS-2YR 27    27                      | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M  M       |  3       |
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  FIBROSARCOMA                              |                X                                                          |         1|
  HEMANGIOSARCOMA                           |                                                                   X       |         1|
  LYMPHOMA MALIGNANT                        |                                                             X             |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
BRAIN,CEREBELLUM                            | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +       | 45       |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                                                 X                         |         4|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            | X                                                                         |         4|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                             X                                        |         3|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  141
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:46.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 5| 7| 7| 7| 7| 2| 2| 2| 2| 4| 5| 5| 5| 1| 1| 1| 1| 1| 1| 1|         U      O|
CONTRL MS-2YR 27    27                      | 1| 2| 3| 4| 6| 7| 8| 9| 0| 1| 2| 3| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  ADENOMA                                   |          X                                   X     X                      |         4|
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +       | 44       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  142
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:48.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
                                            | 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
                                            | 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4|   U      O|
10MG   MS-2YR 28    28                      | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +                                                  +  +          |          |
GALLBLADDER                                 | A  +  +  +                                                  +  +          |          |
INTESTINE LARGE                             | +  A  A  +                                                  +  +          |          |
INTESTINE LARGE,CECUM                       | +  A  A  +                                                  +  +          |          |
INTESTINE LARGE,COLON                       | +  A  A  +                                                  +  +          |          |
INTESTINE LARGE,RECTUM                      | +  A  A  +                                                  +  +          |          |
INTESTINE SMALL                             | +  A  A  +                                                  +  +          |          |
INTESTINE SMALL,DUODENUM                    | +  A  A  +                                                  +  +          |          |
INTESTINE SMALL,ILEUM                       | +  A  A  +                                                  +  +          |          |
INTESTINE SMALL,JEJUNUM                     | +  A  A  +                                                  +  +          |          |
  ADENOCARCINOMA                            |                                                                           |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CHOLANGIOCARCINOMA                        |       X                                                                   |          |
  HEMANGIOSARCOMA                           |                                                       X                   |          |
  HEPATOCELLULAR ADENOMA                    |                      X     X                       X                      |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |          |
  HEPATOCELLULAR CARCINOMA                  |          X     X     X                                   X     X        X |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                       X                   |          |
PANCREAS                                    | +  +  M  +                                                  +  +          |          |
SALIVARY GLANDS                             | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
STOMACH                                     | +  +  A  +                                                  +  +          |          |
STOMACH,FORESTOMACH                         | +  +  A  +                                                  +  +          |          |
STOMACH,GLANDULAR                           | +  +  A  +                                                  +  +          |          |
TONGUE                                      | +  +  +  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +                                                  +  +          |          |
BLOOD VESSEL,AORTA                          | +  +  +  +                                                  +  +          |          |
HEART                                       | +  +  +  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | M  +  +  +                                                  +  +          |          |
ADRENAL GLAND,CORTEX                        | M  +  +  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  143
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:49.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
                                            | 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
                                            | 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4|   U      O|
10MG   MS-2YR 28    28                      | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

  LYMPHOMA MALIGNANT                        |                                                                           |          |
ADRENAL GLAND,MEDULLA                       | M  +  +  +                                                  +  +          |          |
ISLETS, PANCREATIC                          | +  +  M  +                                                  +  +          |          |
PARATHYROID GLAND                           | +  +  M  +                                                  +  +          |          |
PITUITARY GLAND                             | M  +  M  +                                                  +  +          |          |
THYROID GLAND                               | +  +  A  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +                                                  +  +          |          |
EPIDIDYMIS                                  | +  +  +  M                                                  +  +          |          |
PENIS                                       |                                                                         + |          |
PREPUTIAL GLAND                             | +  +  +  M        +                    +  +                 +  +          |          |
PROSTATE                                    | +  +  +  M                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SEMINAL VESICLE                             | +  +  +  +                                                  +  +          |          |
TESTES                                      | +  +  +  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE                                  | +  +  +  +     +           +                          +     +  +          |          |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                       X                   |          |
LYMPH NODE,MANDIBULAR                       | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LYMPH NODE,MESENTERIC                       | A  M  A  +     +           +                                +  +          |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
SPLEEN                                      | +  +  M  +                                +           +     +  +          |          |
  HEMANGIOSARCOMA                           |                                           X                               |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |                                                       X                   |          |
THYMUS                                      | M  +  +  M                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  144
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:49.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
                                            | 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
                                            | 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4|   U      O|
10MG   MS-2YR 28    28                      | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M                                                  M  M          |          |
SKIN                                        | +  +  +  +                                                  +  +          |          |
  HEMANGIOMA                                |                                                                           |          |
  PAPILLOMA                                 |                                                                           |          |
  SCHWANNOMA MALIGNANT                      |    X                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +                                                  +  +          |          |
BONE,FEMUR                                  | +  +  +  +                                                  +  +          |          |
BONE,STERNUM                                | +  +  +  +                                                  +  +          |          |
SKELETAL MUSCLE                             | +  +  +  +                 +                                +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
  SCHWANNOMA MALIGNANT                      |    X                       X                                              |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +                                                  +  +          |          |
BRAIN,CEREBELLUM                            | +  +  +  +                                                  +  +          |          |
BRAIN,CEREBRUM                              | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
PERIPHERAL NERVE                            | +  +  +  +                                                  +  +          |          |
SPINAL CORD                                 | +  +  +  +                                                  +  +          |          |
SPINAL CORD,THORACIC                        | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  +                                                  +  +          |          |
LUNG                                        | +  +  +  +     +                                            +  +          |          |
  CHOLANGIOCARCINOMA,METASTATIC,LIVER       |       X                                                                   |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |          X     X                                               X          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
NOSE                                        | +  +  +  +                                                  +  +          |          |
TRACHEA                                     | +  +  +  +                                                  +  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  145
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:49.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 5| 6| 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 1| 7| 7| 7| 7|
                                            | 5| 8| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 7| 2| 4| 4| 4|
                                            | 2| 6| 4| 3| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 3| 3| 3| 8| 8| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3|   S      M|
                                            | 3| 6| 7| 8| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 9| 2| 3| 3| 4| 6| 3| 4| 4| 4|   U      O|
10MG   MS-2YR 28    28                      | 7| 7| 5| 0| 6| 7| 8| 9| 6| 7| 8| 9| 5| 6| 7| 8| 3| 8| 9| 0| 5| 0| 5| 6| 7|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         | A  +  +  +                             +                    +  +          |          |
HARDERIAN GLAND                             | +  +  +  +                             +        +           +  +          |          |
  ADENOMA                                   |                                        X        X                         |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
LACRIMAL GLAND                              | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
ZYMBAL'S GLAND                              | +  +  +  M                                                  M  +          |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +                                      +           +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
URINARY BLADDER                             | +  +  +  +                                                  +  +          |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  146
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:49.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|         S      M|
                                            | 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3|         U      O|
10MG   MS-2YR 28    28                      | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |             +                                                             |  7       |
GALLBLADDER                                 |             +                                                             |  6       |
INTESTINE LARGE                             |             +                                                             |  5       |
INTESTINE LARGE,CECUM                       |             +                                                             |  5       |
INTESTINE LARGE,COLON                       |             +                                                             |  5       |
INTESTINE LARGE,RECTUM                      |             +                                                             |  5       |
INTESTINE SMALL                             |             +                                               +             |  6       |
INTESTINE SMALL,DUODENUM                    |             +                                                             |  5       |
INTESTINE SMALL,ILEUM                       |             +                                                             |  5       |
INTESTINE SMALL,JEJUNUM                     |             +                                               +             |  6       |
  ADENOCARCINOMA                            |                                                             X             |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  CHOLANGIOCARCINOMA                        |                                                                           |         1|
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HEPATOCELLULAR ADENOMA                    |    X                             X           X                            |         6|
  HEPATOCELLULAR ADENOMA,MULTIPLE           | X     X                                                                   |         2|
  HEPATOCELLULAR CARCINOMA                  |          X                                         X  X     X             |        10|
  HISTIOCYTIC SARCOMA                       |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |             X              X                                              |         3|
PANCREAS                                    |             +                                                             |  6       |
SALIVARY GLANDS                             |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
STOMACH                                     |             +                                                             |  6       |
STOMACH,FORESTOMACH                         |             +                                                             |  6       |
STOMACH,GLANDULAR                           |             +                                                             |  6       |
TONGUE                                      |             +                                                             |  7       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |             +                                                             |  7       |
BLOOD VESSEL,AORTA                          |             +                                                             |  7       |
HEART                                       |             +                                                             |  7       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |             +                                                             |  6       |
ADRENAL GLAND,CORTEX                        |             +                                                             |  6       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  147
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:50.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|         S      M|
                                            | 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3|         U      O|
10MG   MS-2YR 28    28                      | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
ADRENAL GLAND,MEDULLA                       |             +                                                             |  6       |
ISLETS, PANCREATIC                          |             +                                                             |  6       |
PARATHYROID GLAND                           |             +                                                             |  6       |
PITUITARY GLAND                             |             +                                                             |  5       |
THYROID GLAND                               |             +                                                             |  6       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           |             +                                                             |  7       |
EPIDIDYMIS                                  |             +                                                             |  6       |
PENIS                                       |                                                                           |  1       |
PREPUTIAL GLAND                             |             +     +                                                       | 10       |
PROSTATE                                    |             +                                                             |  6       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
SEMINAL VESICLE                             |             +                                                     +       |  8       |
TESTES                                      |             +                                                             |  7       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
LYMPH NODE                                  |             +                                            +                | 11       |
  HISTIOCYTIC SARCOMA,RENAL                 |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
LYMPH NODE,MESENTERIC                       |             +                                            +                |  7       |
  HISTIOCYTIC SARCOMA                       |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
SPLEEN                                      |             +              +                             +  +             | 11       |
  HEMANGIOSARCOMA                           |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                          X                |         1|
  LYMPHOMA MALIGNANT                        |             X              X                                              |         3|
THYMUS                                      |             +                                                             |  5       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  148
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:50.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|         S      M|
                                            | 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3|         U      O|
10MG   MS-2YR 28    28                      | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |             M                                                             |  0       |
SKIN                                        | +  +        +                                                             |  9       |
  HEMANGIOMA                                | X                                                                         |         1|
  PAPILLOMA                                 |    X                                                                      |         1|
  SCHWANNOMA MALIGNANT                      |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |             +                                                             |  7       |
BONE,FEMUR                                  |             +                                                             |  7       |
BONE,STERNUM                                |             +                                                             |  7       |
SKELETAL MUSCLE                             |             +                                                             |  8       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
  SCHWANNOMA MALIGNANT                      |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |             +                                                             |  7       |
BRAIN,CEREBELLUM                            |             +                                                             |  7       |
BRAIN,CEREBRUM                              |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
PERIPHERAL NERVE                            |             +                                                             |  7       |
SPINAL CORD                                 |             +                                                             |  7       |
SPINAL CORD,THORACIC                        |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |             +                                                             |  6       |
LUNG                                        |             +                                                             |  8       |
  CHOLANGIOCARCINOMA,METASTATIC,LIVER       |                                                                           |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         3|
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
NOSE                                        |             +                                                             |  7       |
TRACHEA                                     |             +                                                             |  7       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  149
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:50.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 3| 3| 3| 3| 0| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 3| 3| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 5| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7|         S      M|
                                            | 6| 7| 7| 7| 8| 1| 1| 1| 4| 4| 4| 9| 0| 0| 0| 0| 0| 0| 0| 3| 3| 3| 3|         U      O|
10MG   MS-2YR 28    28                      | 9| 0| 1| 2| 8| 3| 4| 5| 3| 4| 5| 9| 0| 1| 2| 3| 4| 5| 6| 0| 1| 2| 3|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
SPECIAL SENSES SYSTEM

EYE                                         |             +                                                             |  7       |
HARDERIAN GLAND                             | +           +                                                             | 10       |
  ADENOMA                                   | X                                                                         |         3|
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
LACRIMAL GLAND                              |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
ZYMBAL'S GLAND                              |             M                                                             |  4       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |             +                                                             |  8       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
URINARY BLADDER                             |             +                                                             |  7       |
  LYMPHOMA MALIGNANT                        |             X                                                             |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  150
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:51.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5|   U      O|
25MG   MS-2YR 29    29                      | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +                                                                      |          |
GALLBLADDER                                 | +  M                                                                      |          |
INTESTINE LARGE                             | +  A                                                                      |          |
INTESTINE LARGE,CECUM                       | +  A                                                                      |          |
INTESTINE LARGE,COLON                       | +  A                                                                      |          |
INTESTINE LARGE,RECTUM                      | +  A                                                                      |          |
INTESTINE SMALL                             | A  A                                                                      |          |
INTESTINE SMALL,DUODENUM                    | A  A                                                                      |          |
  LYMPHOMA MALIGNANT                        |                                                                           |          |
INTESTINE SMALL,ILEUM                       | A  A                                                                      |          |
INTESTINE SMALL,JEJUNUM                     | A  A                                                                      |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |                                                       X                   |          |
  HEPATOCELLULAR ADENOMA                    |       X                                         X     X           X     X |          |
  HEPATOCELLULAR CARCINOMA                  |    X                                                                      |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                        X                                  |          |
PANCREAS                                    | +  +                                                                      |          |
SALIVARY GLANDS                             | +  +                                                                      |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
STOMACH                                     | +  A                                                                      |          |
STOMACH,FORESTOMACH                         | +  A                                                                      |          |
STOMACH,GLANDULAR                           | +  A                                                                      |          |
TONGUE                                      | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +                                                                      |          |
BLOOD VESSEL,AORTA                          | +  +                                                                      |          |
HEART                                       | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +                                                                      |          |
ADRENAL GLAND,CORTEX                        | +  +                                                                      |          |
ADRENAL GLAND,MEDULLA                       | +  +                                                                      |          |
ISLETS, PANCREATIC                          | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  151
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:51.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5|   U      O|
25MG   MS-2YR 29    29                      | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

  ADENOMA                                   |                                                                           |          |
PARATHYROID GLAND                           | +  +                                                                      |          |
PITUITARY GLAND                             | +  A                                                                      |          |
THYROID GLAND                               | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  A                                                                      |          |
EPIDIDYMIS                                  | +  +                                                                      |          |
PREPUTIAL GLAND                             | +  M                             +                                +       |          |
PROSTATE                                    | +  +                                                                      |          |
SEMINAL VESICLE                             | +  A                                                                      |          |
TESTES                                      | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +                                                                      |          |
LYMPH NODE                                  | +  +                                   +        +                         |          |
LYMPH NODE,MANDIBULAR                       | +  +                                                                      |          |
LYMPH NODE,MESENTERIC                       | +  +                                   +        +                         |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
SPLEEN                                      | +  +                                   +  +                               |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
  LYMPHOMA MALIGNANT                        |                                        X                                  |          |
THYMUS                                      | +  M                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M                                                                      |          |
SKIN                                        | +  +  +                                                                   |          |
  FIBROSARCOMA                              |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +                                                                      |          |
BONE,FEMUR                                  | +  +                                                                      |          |
BONE,STERNUM                                | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  152
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:51.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 1| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 1| 7| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 3| 3| 3| 3| 3| 3| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3|   S      M|
                                            | 7| 0| 2| 2| 2| 2| 5| 5| 5| 5| 8| 8| 8| 8| 1| 1| 1| 1| 2| 2| 2| 3| 3| 3| 5|   U      O|
25MG   MS-2YR 29    29                      | 9| 7| 4| 5| 6| 7| 4| 5| 6| 7| 4| 5| 6| 7| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 5|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

SKELETAL MUSCLE                             | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +                                                                      |          |
BRAIN,CEREBELLUM                            | +  +                                                                      |          |
BRAIN,CEREBRUM                              | +  +                                                                      |          |
PERIPHERAL NERVE                            | +  +                                                                      |          |
SPINAL CORD                                 | +  +                                                                      |          |
SPINAL CORD,THORACIC                        | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  M                                                                      |          |
LUNG                                        | +  +                                                                      |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                                                      |          |
  HISTIOCYTIC SARCOMA                       | X                                                                         |          |
NOSE                                        | +  +                                                                      |          |
TRACHEA                                     | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +                                                                      |          |
HARDERIAN GLAND                             | +  +                                                                      |          |
  ADENOMA                                   |                                                                           |          |
LACRIMAL GLAND                              | +  A                                                                      |          |
ZYMBAL'S GLAND                              | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +                                                                      |          |
URINARY BLADDER                             | +  +                                                                      |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  153
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:51.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   MS-2YR 29    29                      | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   |                                                                           |  2       |
GALLBLADDER                                 |                                                                           |  1       |
INTESTINE LARGE                             |                                                                           |  1       |
INTESTINE LARGE,CECUM                       |                                                                           |  1       |
INTESTINE LARGE,COLON                       |                                                                           |  1       |
INTESTINE LARGE,RECTUM                      |                                                                           |  1       |
INTESTINE SMALL                             |          +                                                                |  1       |
INTESTINE SMALL,DUODENUM                    |          +                                                                |  1       |
  LYMPHOMA MALIGNANT                        |          X                                                                |         1|
INTESTINE SMALL,ILEUM                       |                                                                           |  0       |
INTESTINE SMALL,JEJUNUM                     |                                                                           |  0       |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEMANGIOSARCOMA                           |                                  X                                        |         2|
  HEPATOCELLULAR ADENOMA                    |                            X     X           X  X     X     X     X       |        12|
  HEPATOCELLULAR CARCINOMA                  |          X  X  X  X                       X                               |         6|
  HISTIOCYTIC SARCOMA                       |                                  X                                        |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
PANCREAS                                    |                                                                           |  2       |
SALIVARY GLANDS                             |                                  +                                        |  3       |
  HISTIOCYTIC SARCOMA                       |                                  X                                        |         1|
STOMACH                                     |                                                                           |  1       |
STOMACH,FORESTOMACH                         |                                                                           |  1       |
STOMACH,GLANDULAR                           |                                                                           |  1       |
TONGUE                                      |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                |                                                                           |  2       |
BLOOD VESSEL,AORTA                          |                                                                           |  2       |
HEART                                       |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               |                                                                           |  2       |
ADRENAL GLAND,CORTEX                        |                                                                           |  2       |
ADRENAL GLAND,MEDULLA                       |                                                                           |  2       |
ISLETS, PANCREATIC                          |                      +                                                    |  3       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  154
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:52.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   MS-2YR 29    29                      | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

  ADENOMA                                   |                      X                                                    |         1|
PARATHYROID GLAND                           |                                                                           |  2       |
PITUITARY GLAND                             |                                                                           |  1       |
THYROID GLAND                               |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           |                                                                           |  1       |
EPIDIDYMIS                                  |                                                                           |  2       |
PREPUTIAL GLAND                             |                                           +  +                    +       |  6       |
PROSTATE                                    |                                                                           |  2       |
SEMINAL VESICLE                             |                                                                           |  1       |
TESTES                                      |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 |                                                                           |  2       |
LYMPH NODE                                  |                                                                           |  4       |
LYMPH NODE,MANDIBULAR                       |                                                                           |  2       |
LYMPH NODE,MESENTERIC                       |                                                                           |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
SPLEEN                                      |                                                                           |  4       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
THYMUS                                      |                                                                           |  1       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               |                                                                           |  0       |
SKIN                                        |                                                                           |  3       |
  FIBROSARCOMA                              |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        |                                                                           |  2       |
BONE,FEMUR                                  |                                                                           |  2       |
BONE,STERNUM                                |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  155
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:22:52.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 2| 2| 2| 3| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 6| 6|         S      M|
                                            | 5| 5| 5| 8| 8| 8| 8| 2| 2| 2| 2| 5| 5| 5| 5| 2| 2| 2| 2| 2| 2| 2| 2|         U      O|
25MG   MS-2YR 29    29                      | 6| 7| 8| 0| 1| 2| 3| 4| 5| 6| 7| 3| 4| 5| 6| 0| 1| 2| 3| 4| 5| 6| 7|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
MUSCULOSKELETAL SYSTEM

SKELETAL MUSCLE                             |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       |                                                                           |  2       |
BRAIN,CEREBELLUM                            |                                                                           |  2       |
BRAIN,CEREBRUM                              |                                                                           |  2       |
PERIPHERAL NERVE                            |                                                                           |  2       |
SPINAL CORD                                 |                                                                           |  2       |
SPINAL CORD,THORACIC                        |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      |                                                                           |  1       |
LUNG                                        | +              +                                                          |  4       |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            | X              X                                                          |         2|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
NOSE                                        |                                                                           |  2       |
TRACHEA                                     |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         |                                                                           |  2       |
HARDERIAN GLAND                             |                                  +  +                                     |  4       |
  ADENOMA                                   |                                  X  X                                     |         2|
LACRIMAL GLAND                              |                                                                           |  1       |
ZYMBAL'S GLAND                              |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      |                                                                           |  2       |
URINARY BLADDER                             |                                                                           |  2       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  156
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:00.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
                                            | 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
                                            | 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3|   S      M|
                                            | 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2|   U      O|
50MG   MS-2YR 30    30                      | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
GALLBLADDER                                 | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  M |          |
INTESTINE LARGE                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,CECUM                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
INTESTINE LARGE,COLON                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE LARGE,RECTUM                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL                             | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,DUODENUM                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,ILEUM                       | A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
INTESTINE SMALL,JEJUNUM                     | A  +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |                                                          X                |          |
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEPATOCELLULAR ADENOMA                    |    X                 X     X                 X        X                   |          |
  HEPATOCELLULAR ADENOMA,MULTIPLE           | X                                                  X           X          |          |
  HEPATOCELLULAR CARCINOMA                  | X           X        X           X     X                          X     X |          |
  HEPATOCELLULAR CARCINOMA,MULTIPLE         |                                           X                               |          |
  HISTIOCYTIC SARCOMA                       |                                     X                                     |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
PANCREAS                                    | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
STOMACH                                     | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
STOMACH,FORESTOMACH                         | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
STOMACH,GLANDULAR                           | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BLOOD VESSEL,AORTA                          | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  157
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:00.1
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
                                            | 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
                                            | 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3|   S      M|
                                            | 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2|   U      O|
50MG   MS-2YR 30    30                      | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,METASTATIC,LUNG                 |                      X                                                    |          |
ADRENAL GLAND,CORTEX                        | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ADENOMA                                   |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
ADRENAL GLAND,MEDULLA                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
ISLETS, PANCREATIC                          | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PARATHYROID GLAND                           | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PITUITARY GLAND                             | M  M  +  +  +  +  +  M  +  +  +  +  +  +  +  +  M  +  +  +  +  +  M  M  M |          |
THYROID GLAND                               | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |       +                                                                   |          |
  LYMPHOMA MALIGNANT,THORACIC               |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PREPUTIAL GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
PROSTATE                                    | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
SEMINAL VESICLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HISTIOCYTIC SARCOMA                       |                                     X                                     |          |
LYMPH NODE                                  | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE,AX|                                                                           |          |
      ILLARY                                |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  158
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:00.2
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
                                            | 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
                                            | 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3|   S      M|
                                            | 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2|   U      O|
50MG   MS-2YR 30    30                      | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE,TH|                                                                           |          |
      ORACIC                                |                                                                           |          |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |                                                          X                |          |
LYMPH NODE,MANDIBULAR                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE   |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
LYMPH NODE,MESENTERIC                       | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  + |          |
  HISTIOCYTIC SARCOMA                       |                                     X                                     |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
SPLEEN                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  HEMANGIOSARCOMA                           |    X                                                              X       |          |
  HISTIOCYTIC SARCOMA                       |                                     X                                     |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
THYMUS                                      | M  M  +  +  +  +  +  +  +  +  +  M  +  +  M  +  +  +  +  +  +  +  +  M  M |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  +  M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M  M |          |
  HISTIOCYTIC SARCOMA                       |                                                                           |          |
SKIN                                        | +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
  SARCOMA                                   |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  FIBROSARCOMA,BACK                         |                                                                           |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  159
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:00.3
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
                                            | 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
                                            | 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3|   S      M|
                                            | 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2|   U      O|
50MG   MS-2YR 30    30                      | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  + |          |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LUNG                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |                            X                             X        X       |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                      X                                                    |          |
  ALVEOLAR/BRONCHIOLAR CARCINOMA,MULTIPLE   |                         X                                                 |          |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE   |                                                                           |          |
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |                                                                           |          |
  HISTIOCYTIC SARCOMA                       |                                     X                                     |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
TRACHEA                                     | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
LACRIMAL GLAND                              | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  LYMPHOMA MALIGNANT                        |       X                                                                   |          |
ZYMBAL'S GLAND                              | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
  CARCINOMA,METASTATIC,LUNG                 |                      X                                                    |          |
  LYMPHOMA MALIGNANT                        |       X                                                  X                |          |
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  + |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  160
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:00.4
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 6| 6| 6|
                                            | 0| 2| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 2| 7| 9|
                                            | 9| 1| 5| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3| 3| 4| 4| 3| 3| 3| 3| 3| 3| 1| 8| 6|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|   S      U|
MALE                        CARCASS ID      | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 3| 3|   S      M|
                                            | 0| 0| 1| 3| 3| 3| 3| 6| 6| 6| 6| 9| 9| 9| 2| 2| 3| 3| 3| 3| 6| 6| 9| 1| 2|   U      O|
50MG   MS-2YR 30    30                      | 4| 6| 1| 2| 3| 4| 5| 2| 3| 4| 5| 2| 3| 4| 1| 2| 4| 5| 6| 7| 1| 2| 2| 1| 4|   E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  161
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:07.5
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7|         S      M|
                                            | 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2|         U      O|
50MG   MS-2YR 30    30                      | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
GALLBLADDER                                 | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 43       |
INTESTINE LARGE                             | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,CECUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
INTESTINE LARGE,COLON                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
INTESTINE LARGE,RECTUM                      | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 45       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
INTESTINE SMALL,ILEUM                       | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
INTESTINE SMALL,JEJUNUM                     | +  A  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 45       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LIVER                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HEPATOCELLULAR ADENOMA                    |                            X     X                    X                   |         8|
  HEPATOCELLULAR ADENOMA,MULTIPLE           |                                                                           |         3|
  HEPATOCELLULAR CARCINOMA                  |    X                                X              X              X       |        11|
  HEPATOCELLULAR CARCINOMA,MULTIPLE         |                                                                           |         1|
  HISTIOCYTIC SARCOMA                       |                X                                                          |         2|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
PANCREAS                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
TONGUE                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
BLOOD VESSEL,AORTA                          | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
HEART                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  162
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:07.6
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7|         S      M|
                                            | 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2|         U      O|
50MG   MS-2YR 30    30                      | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  CARCINOMA,METASTATIC,LUNG                 |                                                                           |         1|
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ADENOMA                                   |          X                                                                |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +       | 46       |
PITUITARY GLAND                             | M  M  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  M  +  +  +  M  +       | 36       |
THYROID GLAND                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
GENERAL BODY SYSTEM

TISSUE NOS                                  |                                                                   M       |  1       |
  LYMPHOMA MALIGNANT,THORACIC               |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
GENITAL SYSTEM

COAGULATING GLAND                           | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
EPIDIDYMIS                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PREPUTIAL GLAND                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
PROSTATE                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
SEMINAL VESICLE                             | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
TESTES                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
LYMPH NODE                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE,AX| X                                                                         |         1|
      ILLARY                                |                                                                           |          |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  163
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:07.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7|         S      M|
                                            | 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2|         U      O|
50MG   MS-2YR 30    30                      | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE,TH| X                                                                         |         1|
      ORACIC                                |                                                                           |          |
HEMATOPOIETIC SYSTEM

  LYMPHOMA MALIGNANT,RENAL                  |                                                                           |         1|
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 46       |
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE   | X                                                                         |         1|
  HISTIOCYTIC SARCOMA                       |                X                                                          |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 46       |
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
SPLEEN                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  HEMANGIOSARCOMA                           |                                                                           |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
THYMUS                                      | M  M  +  +  M  M  +  +  +  +  +  M  +  +  +  +  +  M  +  M  +  +  +       | 35       |
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | M  M  M  M  M  +  M  M  M  M  M  M  M  M  M  M  M  M  M  +  M  M  M       |  4       |
  HISTIOCYTIC SARCOMA                       |                X                                                          |         1|
SKIN                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
  SARCOMA                                   |                                     X                                     |         1|
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  FIBROSARCOMA,BACK                         | X                                                                         |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  164
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:07.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7|         S      M|
                                            | 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2|         U      O|
50MG   MS-2YR 30    30                      | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M       | 46       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
------------------------------------------------------------------------------------------------------------------------------------
RESPIRATORY SYSTEM

LARYNX                                      | M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +       | 45       |
LUNG                                        | +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  ALVEOLAR/BRONCHIOLAR ADENOMA              |    X        X              X                                X             |         7|
  ALVEOLAR/BRONCHIOLAR CARCINOMA            |                                           X     X                         |         3|
  ALVEOLAR/BRONCHIOLAR CARCINOMA,MULTIPLE   |                                                                           |         1|
  FIBROSARCOMA,METASTATIC,SKELETAL MUSCLE   | X                                                                         |         1|
  HEPATOCELLULAR CARCINOMA,METASTATIC,LIVER |    X                                               X                      |         2|
  HISTIOCYTIC SARCOMA                       |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
NOSE                                        | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
TRACHEA                                     | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 48       |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  LYMPHOMA MALIGNANT                        |                                                                           |         1|
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  M       | 45       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +       | 47       |
  CARCINOMA,METASTATIC,LUNG                 |                                                                           |         1|
  LYMPHOMA MALIGNANT                        |                                                                           |         2|
URINARY BLADDER                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +       | 47       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  165
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:08.0
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|
                                            | 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|
                                            | 0| 1| 2| 2| 2| 3| 3| 3| 2| 2| 2| 2| 3| 3| 3| 4| 4| 4| 4| 4| 4| 3| 3|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|         S      U|
MALE                        CARCASS ID      | 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 6| 6| 6| 6| 6| 6| 7| 7|         S      M|
                                            | 2| 2| 4| 4| 5| 7| 7| 7| 1| 1| 1| 1| 4| 4| 4| 0| 0| 0| 1| 1| 1| 2| 2|         U      O|
50MG   MS-2YR 30    30                      | 5| 8| 8| 9| 0| 3| 4| 5| 6| 7| 8| 9| 6| 7| 8| 7| 8| 9| 0| 1| 2| 8| 9|         E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  166
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:09.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 0| 0| 0| 0| 0| 0| 1| 1|                                                      U      O|
100MG  F120 DAYS    36                      | 4| 5| 6| 7| 8| 9| 0| 1|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +                                                    |  8       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,DUODENUM                    | +  +  +  +  +  M  +  +                                                    |  7       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +                                                    |  8       |
LIVER                                       | +  +  +  +  +  +  +  +                                                    |  8       |
PANCREAS                                    | +  +  +  +  +  +  +  +                                                    |  8       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH                                     | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +                                                    |  8       |
TONGUE                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  +  M  M  +  +                                                    |  6       |
BLOOD VESSEL,AORTA                          | +  +  +  +  M  M  +  +                                                    |  6       |
HEART                                       | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,MEDULLA                       | +  +  +  +  +  +  +  +                                                    |  8       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +                                                    |  8       |
PARATHYROID GLAND                           | +  +  +  +  +  +  +  M                                                    |  7       |
PITUITARY GLAND                             | +  +  +  +  +  M  +  +                                                    |  7       |
THYROID GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  167
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:09.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 0| 0| 0| 0| 0| 0| 1| 1|                                                      U      O|
100MG  F120 DAYS    36                      | 4| 5| 6| 7| 8| 9| 0| 1|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

CLITORAL GLAND                              | +  +  +  M  +  +  M  M                                                    |  5       |
OVARY                                       | +  +  +  +  +  +  +  +                                                    |  8       |
UTERUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
VAGINA                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +                                                    |  8       |
SPLEEN                                      | +  +  +  +  +  +  +  +                                                    |  8       |
THYMUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
SKIN                                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +                                                    |  8       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +                                                    |  8       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  168
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:09.9
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 0| 0| 0| 0| 0| 0| 1| 1|                                                      U      O|
100MG  F120 DAYS    36                      | 4| 5| 6| 7| 8| 9| 0| 1|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  +  +  +  M  M  +  +                                                    |  6       |
LUNG                                        | +  +  +  +  +  +  +  +                                                    |  8       |
NOSE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
TRACHEA                                     | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +                                                    |  8       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
LACRIMAL GLAND                              | +  +  +  +  +  +  +  +                                                    |  8       |
ZYMBAL'S GLAND                              | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +                                                    |  8       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  169
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:11.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 3| 3| 3| 3| 3| 3| 3|                                                      U      O|
100MG  F210 DAYS    37                      | 9| 0| 1| 2| 3| 4| 5| 6|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
ALIMENTARY SYSTEM

ESOPHAGUS                                   | +  +  +  +  +  +  +  +                                                    |  8       |
GALLBLADDER                                 | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,CECUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,COLON                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE LARGE,RECTUM                      | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL                             | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,DUODENUM                    | +  M  +  +  +  +  +  +                                                    |  7       |
INTESTINE SMALL,ILEUM                       | +  +  +  +  +  +  +  +                                                    |  8       |
INTESTINE SMALL,JEJUNUM                     | +  +  +  +  +  +  +  +                                                    |  8       |
LIVER                                       | +  +  +  +  +  +  +  +                                                    |  8       |
PANCREAS                                    | +  +  +  +  +  +  +  +                                                    |  8       |
SALIVARY GLANDS                             | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH                                     | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,FORESTOMACH                         | +  +  +  +  +  +  +  +                                                    |  8       |
STOMACH,GLANDULAR                           | +  +  +  +  +  +  +  +                                                    |  8       |
TONGUE                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
CARDIOVASCULAR SYSTEM

BLOOD VESSEL                                | +  +  +  M  +  +  +  +                                                    |  7       |
BLOOD VESSEL,AORTA                          | +  +  +  M  +  +  +  +                                                    |  7       |
HEART                                       | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
ENDOCRINE SYSTEM

ADRENAL GLAND                               | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,CORTEX                        | +  +  +  +  +  +  +  +                                                    |  8       |
ADRENAL GLAND,MEDULLA                       | +  M  +  +  +  +  +  +                                                    |  7       |
ISLETS, PANCREATIC                          | +  +  +  +  +  +  +  +                                                    |  8       |
PARATHYROID GLAND                           | +  M  +  M  +  +  +  +                                                    |  6       |
PITUITARY GLAND                             | +  M  +  M  +  M  M  M                                                    |  3       |
THYROID GLAND                               | M  M  +  +  +  +  +  +                                                    |  6       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  170
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:11.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 3| 3| 3| 3| 3| 3| 3|                                                      U      O|
100MG  F210 DAYS    37                      | 9| 0| 1| 2| 3| 4| 5| 6|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
GENITAL SYSTEM

CLITORAL GLAND                              | M  M  +  +  M  M  +  +                                                    |  4       |
OVARY                                       | +  +  +  +  +  +  +  +                                                    |  8       |
UTERUS                                      | +  +  +  +  +  +  +  +                                                    |  8       |
VAGINA                                      | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
HEMATOPOIETIC SYSTEM

BONE MARROW                                 | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE                                  | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MANDIBULAR                       | +  +  +  +  +  +  +  +                                                    |  8       |
LYMPH NODE,MESENTERIC                       | +  +  +  +  +  +  +  +                                                    |  8       |
SPLEEN                                      | +  +  +  +  +  +  +  +                                                    |  8       |
THYMUS                                      | M  +  +  +  +  +  +  +                                                    |  7       |
------------------------------------------------------------------------------------------------------------------------------------
INTEGUMENTARY SYSTEM

MAMMARY GLAND                               | +  +  M  +  +  +  +  +                                                    |  7       |
SKIN                                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
MUSCULOSKELETAL SYSTEM

BONE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,FEMUR                                  | +  +  +  +  +  +  +  +                                                    |  8       |
BONE,STERNUM                                | +  +  +  +  +  +  +  +                                                    |  8       |
SKELETAL MUSCLE                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
NERVOUS SYSTEM

BRAIN                                       | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBELLUM                            | +  +  +  +  +  +  +  +                                                    |  8       |
BRAIN,CEREBRUM                              | +  +  +  +  +  +  +  +                                                    |  8       |
PERIPHERAL NERVE                            | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD                                 | +  +  +  +  +  +  +  +                                                    |  8       |
SPINAL CORD,THORACIC                        | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  171
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:11.8
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 2| 2| 2| 2| 2| 2| 2| 2|
                                            | 1| 1| 1| 1| 1| 1| 1| 1|
                                            | 0| 0| 0| 0| 0| 0| 0| 0|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0| 0|                                                      I      T|
Mice-C57Bl/6N XC3H/HEN MTN-NCTR             | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      U|
FEMALE                      CARCASS ID      | 0| 0| 0| 0| 0| 0| 0| 0|                                                      S      M|
                                            | 2| 3| 3| 3| 3| 3| 3| 3|                                                      U      O|
100MG  F210 DAYS    37                      | 9| 0| 1| 2| 3| 4| 5| 6|                                                      E      R|
------------------------------------------------------------------------------------------------------------------------   S      S|
---------------------------------------------------------------------------------------------------------------------------------- |
RESPIRATORY SYSTEM

LARYNX                                      | +  M  +  +  +  M  +  M                                                    |  5       |
LUNG                                        | +  +  +  +  +  +  +  +                                                    |  8       |
NOSE                                        | +  +  +  +  +  +  +  +                                                    |  8       |
TRACHEA                                     | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
SPECIAL SENSES SYSTEM

EYE                                         | +  +  +  +  +  +  +  +                                                    |  8       |
HARDERIAN GLAND                             | +  +  +  +  +  +  +  +                                                    |  8       |
LACRIMAL GLAND                              | M  +  +  +  +  +  +  +                                                    |  7       |
ZYMBAL'S GLAND                              | +  +  M  +  +  +  M  +                                                    |  6       |
------------------------------------------------------------------------------------------------------------------------------------
URINARY SYSTEM

KIDNEY                                      | +  +  +  +  +  +  +  +                                                    |  8       |
URINARY BLADDER                             | +  +  +  +  +  +  +  +                                                    |  8       |
------------------------------------------------------------------------------------------------------------------------------------
+ : TISSUE EXAMINED MICROSCOPICALLY                 M : MISSING TISSUE                        1-4 : LESION QUALIFIED AS:
X : LESION PRESENT BUT NOT QUALIFIED                A : AUTOLYSIS PRECLUDES EXAMINATION               1) MINIMAL  3) MODERATE
I : INSUFFICIENT TISSUE                        BLANK : NOT EXAMINED                                     2) MILD    4)MARKED

NCTR EXP/TEST:   211601                                                                                      PAGE:  172
                                             INDIVIDUAL ANIMAL TUMOR PATHOLOGY TABLE                         DATE: 02/03/2000
                                                         PATHOLOGY REPORT 3                                  TIME: 15:23:13.7
---------------------------------------------------------------------------------------------------------------------------------- |
                            DAYS ON         | 0| 0| 0| 0| 0| 0| 0| 0|
                            TEST            | 3| 3| 3| 3| 3| 3| 3| 3|
                                            | 9| 9| 9| 9| 9| 9| 9| 9|
                                            | 2| 2| 2| 2| 2| 2| 2| 2|
------------------------------------------------------------------------------------------------------------------------   T       |
                                            | 0| 0| 0| 0| 0| 0| 0|