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TDMS Study 97013-96 Pathology Tables

NTP  EXP/TEST: 97013-96                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 10/08/03
ROUTE: DOSED WATER                                                                                                TIME: 15:23:42

                                                         EIS REPORT 03
                                                           FINAL/MICE


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013J

       CONTRACT NUMBER:  NO1-ES-65406

       CAS NUMBER:  75-27-4

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-96                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 10/08/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 15:23:42
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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: FEMALE      WEEK ON DOSE: 43     FIRST DOSE: 08/31/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     18.8    0.7         9     44.5    6.1                      9     25.6    5.9

 175 MG/L           10     18.7    0.8         9     43.6    6.0        97.9          9     24.8    5.8

 350 MG/L           10     18.4    0.8        10     43.9    5.8        98.6         10     25.5    5.4

 700 MG/L           10     19.1    0.8         8     40.4    6.2        90.7          8     21.4    5.9




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 SPECIES-STRAIN: P53(C57BL/6)-MICE          SEX: MALE        WEEK ON DOSE: 43     FIRST DOSE: 08/31/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/L             10     23.0    1.1         9     51.6    2.3                      9     28.8    2.0

 175 MG/L           10     22.5    1.3        10     49.1    4.4        95.1         10     26.6    4.3

 350 MG/L           10     23.0    1.0         9     45.6    5.3        88.3          9     22.7    5.3

 700 MG/L           10     22.8    1.3         7     43.7    6.3        84.6          7     20.9    5.0

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