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TDMS Study 97013-97 Pathology Tables

NTP  EXP/TEST: 97013-97                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 1
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 11/04/03
ROUTE: GAVAGE                                                                                                     TIME: 11:46:19

                                                         EIS REPORT 03
                                                 FINAL #1 TG.AC HEMIZYGOUS MICE


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  97013K

       CONTRACT NUMBER:  N01-ES-65406

       CAS NUMBER:  75-27-4

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 97013-97                 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)                           PAGE: 2
TEST TYPE: 26-39 WEEKS                          INITIAL AND CURRENT BODY WEIGHT                                   DATE: 11/04/03
ROUTE: GAVAGE                                               EISRPT03                                              TIME: 11:46:19
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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: FEMALE      WEEK ON DOSE: 42     FIRST DOSE: 09/15/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            10     20.6    1.1         7     29.8    3.1                      7      9.0    3.3

 25 MG/KG           10     20.9    1.1         9     30.4    4.0       102.0          9      9.4    3.5

 50 MG/KG           10     20.7    1.2         9     29.9    2.4       100.3          9      9.4    1.6

 100     MG/KG      10     20.4    0.7         7     33.5    7.5       112.4          7     13.3    7.0




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 SPECIES-STRAIN: TG.AC HEMI-MICE            SEX: MALE        WEEK ON DOSE: 42     FIRST DOSE: 09/15/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 MG/KG            10     24.5    1.2         6     34.4    5.5                      6     10.2    4.4

 25 MG/KG           10     24.3    1.1         6     39.6    4.9       115.1          6     15.0    5.0

 50 MG/KG           10     24.3    1.1         6     34.2    5.1        99.4          6     10.4    4.5

 100     MG/KG      10     23.9    1.6         8     34.2    2.1        99.4          8      9.9    1.8

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