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TDMS Study 88138-03 Pathology Tables

NTP  EXP/TEST: 88138-03                                   BENZOPHENONE                                            PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 07/21/03
ROUTE: DOSED FEED                                                                                                 TIME: 15:07:27

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  88138B

       CONTRACT NUMBER:  N01-ES-55388

       CAS NUMBER:  119-61-9

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 88138-03                                   BENZOPHENONE                                            PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 07/21/03
ROUTE: DOSED FEED                                           EISRPT03                                              TIME: 15:07:27
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 SPECIES-STRAIN: F 344-RATS                 SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 08/17/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 PPM              50    100.9    7.2        32    350.5   25.1                     32    249.3   23.9

 312 PPM            50    100.6    7.5        38    335.8   21.4        95.8         38    235.6   20.6

 625 PPM            50     99.8    6.8        37    314.5   27.8        89.7         37    214.5   26.9

 1250 PPM           50     99.7    7.1        34    295.5   22.0        84.3         34    196.1   21.3




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 SPECIES-STRAIN: F 344-RATS                 SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 08/16/99
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 PPM              50    108.3   10.2        22    484.4   35.4                     22    376.2   32.0

 312 PPM            50    109.4   10.5        27    459.6   27.9        94.8         27    351.4   27.0

 625 PPM            50    108.6    9.5        31    439.4   34.7        90.7         31    331.3   33.7

 1250 PPM           50    110.0   10.1         2    362.5   10.0        74.8          2    269.1   11.8

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