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Target Organs and Levels of Evidence for TR-016

Bioassay of Phosphamidon for Possible Carcinogenicity (CASRN 13171-21-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Phosphamidon
13171-21-6
07/25/1977Pesticide, cholinesterase inhibitor (Merck 1989). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,80,160 PPM/50 PER GROUP
Gulf South Research Institute

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Vascular System (Spleen): HEMANGIOMA OR HEMANGIOSARCOMA
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland C-Cell: ADENOMA OR CARCINOMA
Male Mice: Negative
Female Mice: Negative