National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/14736

Target Organs and Levels of Evidence for TR-041

Bioassay of Chlorothalonil for Possible Carcinogenicity (CASRN 1897-45-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Chlorothalonil
1897-45-6
06/29/1978Fungicide, bactericide, nematocide. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
R: 0,5063,10126 (AVG), FM: 0,3000,6000 (AVG), MM: 0,2688,5375 (AVG) PPM/50 PER GROUP
Gulf South Research Institute

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA
Male Mice: Negative
Female Mice: Negative


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.