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Target Organs and Levels of Evidence for TR-094

Bioassay of 4-Amino-2-nitrophenol for Possible Carcinogenicity (CASRN 119-34-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
4-Amino-2-nitrophenol
119-34-6
04/26/1978Formerly used in permanent hair dye products; fur dyeDosed-Feed
0,1250,2500 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL CARCINOMA)
Female Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL CARCINOMA)
Male Mice: Negative
Female Mice: Negative