National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13419

Target Organs and Levels of Evidence for TR-121

Bioassay of Dimethyl Terephthalate for Possible Carcinogenicity (CASRN 120-61-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Dimethyl terephthalate
120-61-6
12/13/1978Synthesis of polyester fiberDosed-Feed
0,2500,5000 PPM/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA OR CARCINOMA)
Female Mice: Negative


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