Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/13423

Target Organs and Levels of Evidence for TR-123

Bioassay of 2,7-Dichlorodibenzo-p-dioxin (DCDD) for Possible Carcinogenicity (CASRN 33857-26-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
2,7-Dichlorodibenzo-p-dioxin
33857-26-0
01/00/1977By-product in manufacture of a germicide and herbicideDosed-Feed
0,5000,10000 PPM/35R - 50M PER GROUP
IIT Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA OR LEUKEMIA)
  • Vascular System (Unspecified): (HEMANGIOMA OR HEMANGIOSARCOMA)
Female Mice: Negative