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Target Organs and Levels of Evidence for TR-123

Bioassay of 2,7-Dichlorodibenzo-p-dioxin (DCDD) for Possible Carcinogenicity (CASRN 33857-26-0)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
2,7-Dichlorodibenzo-p-dioxin
33857-26-0
01/00/1977By-product in manufacture of a germicide and herbicideDosed-Feed
0,5000,10000 PPM/35R - 50M PER GROUP
IIT Research Institute

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)
  • Hematopoietic System: (LYMPHOMA OR LEUKEMIA)
  • Vascular System (Unspecified): (HEMANGIOMA OR HEMANGIOSARCOMA)
Female Mice: Negative