https://ntp.niehs.nih.gov/go/13441

2,5-Dithiobiurea: Target Organs and Levels of Evidence for TR-132

Bioassay of 2,5-Dithiobiurea for Possible Carcinogenicity (CASRN 142-46-1)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
2,5-Dithiobiurea
142-46-1
10/25/1978 Dosed-Feed
R: 0,.6,1.2, M: 0,1.0,2.0 %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)